Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dana M. Ambruzs"'
Autor:
Camilla A. Richmond, Manasvi S. Shah, Luke T. Deary, Danny C. Trotier, Horatio Thomas, Dana M. Ambruzs, Lijie Jiang, Bristol B. Whiles, Hannah D. Rickner, Robert K. Montgomery, Alessio Tovaglieri, Diana L. Carlone, David T. Breault
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2403-2411 (2015)
The cellular and molecular mechanisms underlying adaptive changes to physiological stress within the intestinal epithelium remain poorly understood. Here, we show that PTEN, a negative regulator of the PI3K→AKT→mTORC1-signaling pathway, is an imp
Externí odkaz:
https://doaj.org/article/cddef076518c4b6d880192dc6ebfe2f1
Autor:
Diana L. Carlone, Rebecca D. Riba‐Wolman, Alessio Tovaglieri, Rudolf Jaenisch, Dana M. Ambruzs, Benjamin E. Mead, Lijie Jiang, David T. Breault, Christopher J. Lengner, Luke T. Deary, Manasvi S. Shah
Publikováno v:
Stem Cells (Dayton, Ohio)
Skeletal progenitor/stem cells (SSCs) play a critical role in postnatal bone growth and maintenance. Telomerase (Tert) activity prevents cellular senescence and is required for maintenance of stem cells in self‐renewing tissues. Here we investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785aab3a86055cfe5fec9ac536b53860
https://pubmed.ncbi.nlm.nih.gov/33438789
https://pubmed.ncbi.nlm.nih.gov/33438789
Autor:
Diana L. Carlone, Luke T. Deary, Camilla A. Richmond, Robert K. Montgomery, David T. Breault, Dana M. Ambruzs, Hannah Rickner, Alessio Tovaglieri, Bristol B. Whiles, Horatio R. Thomas, Manasvi S. Shah, Danny C. Trotier, Lijie Jiang
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2403-2411 (2015)
SummaryThe cellular and molecular mechanisms underlying adaptive changes to physiological stress within the intestinal epithelium remain poorly understood. Here, we show that PTEN, a negative regulator of the PI3K→AKT→mTORC1-signaling pathway, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997b6e6f255e62223899cc6ef4cc6aec
https://doi.org/10.1016/j.celrep.2015.11.035
https://doi.org/10.1016/j.celrep.2015.11.035
Autor:
Justin Kerr, Jonathan R. Kelly, Anindita Bhoumik, Mauro A. Frazier, Mark A. Moorman, Rosemary M. Cesario, Alan D. Agulnick, Robert Srijemac, Evert Kroon, Dana M. Ambruzs, Kevin A. D'Amour, Janice K. Payne, Alistair Wilson, Carl Haakmeester
The PEC-01 cell population, differentiated from human embryonic stem cells (hESCs), contains pancreatic progenitors (PPs) that, when loaded into macroencapsulation devices (to produce the VC-01 candidate product) and transplanted into mice, can matur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1ce24f4e2aa0fbdf05d5d2fd00fa74
https://europepmc.org/articles/PMC4572906/
https://europepmc.org/articles/PMC4572906/
Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells
Autor:
Loredana G. Farilla, Robert K. Montgomery, Daniel E. Henderson, David T. Breault, Camilla A. Richmond, Nana Yaa Baffour-Awuah, Selma Algra, Dana M. Ambruzs, Laura K. Fogli, Diana L. Carlone, Mariette E. G. Kranendonk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(1)
The intestinal epithelium is maintained by a population of rapidly cycling ( Lgr5 + ) intestinal stem cells (ISCs). It has been postulated, however, that slowly cycling ISCs must also be present in the intestine to protect the genome from accumulatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c89978e8950f6f64e9fcd6a1b7155ae
https://pubmed.ncbi.nlm.nih.gov/21173232
https://pubmed.ncbi.nlm.nih.gov/21173232
Autor:
Nicholas Hole, David T. Breault, Daniel E. Henderson, Loredana G. Farilla, Irene M. Min, Robert K. Montgomery, Diana L. Carlone, Dana M. Ambruzs, Selma Algra, Amy J. Wagers
Stem cells hold great promise for regenerative medicine, but remain elusive in many tissues in part because universal markers of “stemness” have not been identified. The ribonucleoprotein complex telomerase catalyzes the extension of chromosome e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329fd6a0c2a3c8fa3c2fb95fa6ac5981
https://europepmc.org/articles/PMC2492454/
https://europepmc.org/articles/PMC2492454/
Autor:
Diana L. Carlone, Robert A. Montgomery, Camilla A. Richmond, David T. Breault, Dana M. Ambruzs
Publikováno v:
Gastroenterology. 138:S-52
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be2dcc334a91cd1d4bf1d0c45fb32d74
https://doi.org/10.1016/s0016-5085(10)60239-9
https://doi.org/10.1016/s0016-5085(10)60239-9
Autor:
Montgomery, Robert K., Carlone, Diana L., Richmond, Camilla A., Farilla, Loredana, Kranendonk, Mariette E. G., Henderson, Daniel E., Baffour-Awuah, Nana Yaa, Dana M. Ambruzs, Foglic, Laura K., Algra, Selma, Breault, David T.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 1/4/2011, Vol. 108 Issue 1, p179-184, 6p, 2 Color Photographs, 3 Graphs