Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Dana M Niedowicz"'
Autor:
Adam M Weidner, Melissa A Bradley, Tina L Beckett, Dana M Niedowicz, Amy L S Dowling, Sergey V Matveev, Harry LeVine, Mark A Lovell, M Paul Murphy
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24930 (2011)
While research supports amyloid-β (Aβ) as the etiologic agent of Alzheimer's disease (AD), the mechanism of action remains unclear. Evidence indicates that adducts of RNA caused by oxidation also represent an early phenomenon in AD. It is currently
Externí odkaz:
https://doaj.org/article/ea059413b8664dab9a31f4f23215b99d
Publikováno v:
Neurobiology of Aging. 128:74-84
Autor:
Peter T. Nelson, Zsombor Gal, Wang-Xia Wang, Dana M. Niedowicz, Sergey C. Artiushin, Samuel Wycoff, Angela Wei, Gregory A. Jicha, David W. Fardo
Publikováno v:
Neurobiology of Disease, Vol 125, Iss , Pp 67-76 (2019)
TDP-43 proteinopathy is very prevalent among the elderly (affecting at least 25% of individuals over 85 years of age) and is associated with substantial cognitive impairment. Risk factors implicated in age-related TDP-43 proteinopathy include commonl
Externí odkaz:
https://doaj.org/article/557f64e4c4c64184a343a72712fea247
Publikováno v:
Journal of Diabetes Research, Vol 2018 (2018)
Sulfonylureas are a class of antidiabetes medications prescribed to millions of individuals worldwide. Rodents have been used extensively to study sulfonylureas in the laboratory. Here, we report the results of studies treating mice with a sulfonylur
Externí odkaz:
https://doaj.org/article/e434cb3123d640549435a04c25f726e2
Publikováno v:
Journal of Thyroid Research
Journal of Thyroid Research, Vol 2021 (2021)
Journal of Thyroid Research, Vol 2021 (2021)
Thyroid hormone (TH) perturbation is a common medical problem. Because of substantial public health impact, prior researchers have studied hyper- and hypothyroidism in animal models. Although most prior research focused on in utero and/or development
Autor:
David W. Fardo, Gregory A. Jicha, Donna W Wilcock, Steven Estus, Angela Wei, Dana M. Niedowicz, Sonya Anderson, Douglas A. Price, Janna H. Neltner, Peter T. Nelson, Benjamin C. Shaw, Linda J. Van Eldik, Sergey Artiushin, Adam D. Bachstetter, Indumati Patel, Erin L. Abner, Bela G Nelson, Lena J Brzezinski, Wang-Xia Wang, Qingwei Huang, Yuriko Katsumata
Publikováno v:
Journal of Neuropathology and Experimental Neurology
We found evidence of late-onset Alzheimer disease (LOAD)-associated genetic polymorphism within an exon of Mucin 6 (MUC6) and immediately downstream from another gene: Adaptor Related Protein Complex 2 Subunit Alpha 2 (AP2A2). PCR analyses on genomic
Autor:
Tina L. Beckett, Dana M. Niedowicz, Christa M. Studzinski, Adam M. Weidner, Robin L. Webb, Christopher J. Holler, Rachel R. Ahmed, Harry LeVine, III, M. Paul Murphy
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 3, Pp 449-456 (2010)
Sporadic inclusion body myositis (sIBM) is a common age-related inflammatory myopathy characterized by the presence of intracellular inclusions that contain the amyloid-β (Aβ) peptide, a derivative of the amyloid precursor protein (APP). Aβ is bel
Externí odkaz:
https://doaj.org/article/f9fd4d5436c54d78a6f802342f23cb4e
Autor:
Samuel Wycoff, David W. Fardo, Peter T. Nelson, Gregory A. Jicha, Angela Wei, Zsombor Gal, Dana M. Niedowicz, Wang-Xia Wang, Sergey Artiushin
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 125, Iss, Pp 67-76 (2019)
Neurobiology of Disease, Vol 125, Iss, Pp 67-76 (2019)
TDP-43 proteinopathy is very prevalent among the elderly (affecting at least 25% of individuals over 85 years of age) and is associated with substantial cognitive impairment. Risk factors implicated in age-related TDP-43 proteinopathy include commonl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88859b146089fa67c75def8038821560
https://europepmc.org/articles/PMC6696921/
https://europepmc.org/articles/PMC6696921/
Autor:
Le Zhang, Jeffrey N. Keller, Annadora J. Bruce-Keller, Tina L. Beckett, Dana M. Niedowicz, M. Paul Murphy, Katharina Kohler, Sun-Ok Fernandez-Kim, Kalavathi Dasuri
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1865(9)
Alzheimer's disease (AD) is the most common age-related neurodegenerative disease, while obesity is a major global public health problem associated with the metabolic disorder type 2 diabetes mellitus (T2DM). Chronic obesity and T2DM have been identi
Publikováno v:
Journal of Diabetes Research, Vol 2018 (2018)
Journal of Diabetes Research
Journal of Diabetes Research
Sulfonylureas are a class of antidiabetes medications prescribed to millions of individuals worldwide. Rodents have been used extensively to study sulfonylureas in the laboratory. Here, we report the results of studies treating mice with a sulfonylur