Scalable and accurate deep learning with electronic health records

Autor: Alvin Rajkomar, Eyal Oren, Kai Chen, Andrew M. Dai, Nissan Hajaj, Michaela Hardt, Peter J. Liu, Xiaobing Liu, Jake Marcus, Mimi Sun, Patrik Sundberg, Hector Yee, Kun Zhang, Yi Zhang, Gerardo Flores, Gavin E. Duggan, Jamie Irvine, Quoc Le, Kurt Litsch, Alexander Mossin, Justin Tansuwan, De Wang, James Wexler, Jimbo Wilson, Dana Ludwig, Samuel L. Volchenboum, Katherine Chou, Michael Pearson, Srinivasan Madabushi, Nigam H. Shah, Atul J. Butte, Michael D. Howell, Claire Cui, Greg S. Corrado, Jeffrey Dean

Publikováno v: npj Digital Medicine, Vol 1, Iss 1, Pp 1-10 (2018)

Artificial intelligence: Algorithm predicts clinical outcomes for hospital inpatients Artificial intelligence outperforms traditional statistical models at predicting a range of clinical outcomes from a patient’s entire raw electronic health record

Externí odkaz: https://doaj.org/article/a9b3a7cdda6e486cba268a16dc6760b2

Protected Health Information filter (Philter): accurately and securely de-identifying free-text clinical notes

Autor: Benjamin S. Glicksberg, Atul J. Butte, Beau Norgeot, Marina Sirota, Dana Ludwig, Kathleen Muenzen, Theodore C. Goldstein, Gabriela Schmajuk, Eugenia Rutenberg, Jinoos Yazdany, Gundolf Schenk, Thomas Peterson, Boris Oskotsky, Xuancheng Fan

Publikováno v: NPJ digital medicine, vol 3, iss 1
npj Digital Medicine, Vol 3, Iss 1, Pp 1-8 (2020)
NPJ Digital Medicine

There is a great and growing need to ascertain what exactly is the state of a patient, in terms of disease progression, actual care practices, pathology, adverse events, and much more, beyond the paucity of data available in structured medical record

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5ea6ff8b9106f081404fec966bf04d
https://doi.org/10.1038/s41746-020-0258-y

Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

Autor: Neil Risch, Pui-Yan Kwok, Yiping Zhan, Stephen K. Van Den Eeden, Eunice Wan, Brad Dispensa, Dana Ludwig, Simon Wong, Gangwu Mei, Michael Mittman, Eric Jorgenson, Sarah Rowell, Tanu Shenoy, Charles P. Quesenberry, Stephanie Hesselson, Lisa A. Croen, Michael H. Shapero, Lawrence Walter, Lawrence H. Kushi, Thomas J. Hoffmann, Teresa Webster, Gurpreet K. Mathauda, Carlos Iribarren, Carol P. Somkin, Yang Cao, Jeremy Gollub, Chia Zau, Sheryl Connell, Mohini Patil, Ling Shen, Marianne Sadler, Mark N. Kvale, Catherine Schaefer, David Chan, Rachel A. Whitmer, Richard Lao, Lori C. Sakoda, Dilrini K. Ranatunga, Andrea Finn, William B. McGuire, David Smethurst, Yontao Lu, Sunita Miles, Jasmin L Eshragh

Publikováno v: Genetics, vol 200, iss 4

The Kaiser Permanente (KP) Research Program on Genes, Environment and Health (RPGEH), in collaboration with the University of California—San Francisco, undertook genome-wide genotyping of >100,000 subjects that constitute the Genetic Epidemiology R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed724b4937d36ad741c28720a33cef11
https://europepmc.org/articles/PMC4574249/

Using health-system-wide data to understand hepatitis B virus prophylaxis and reactivation outcomes in patients receiving rituximab

Autor: Chris Tonner, Marina Sirota, Gabriela Schmajuk, Dana Ludwig, Laura Trupin, Jinoos Yazdany, Sara G. Murray, R. Adams Dudley, Stephen Shiboski, Urmimala Sarkar, Jing Li

Publikováno v: Medicine, vol 96, iss 13
Schmajuk, G; Tonner, C; Trupin, L; Li, J; Sarkar, U; Ludwig, D; et al.(2017). Using health-system-wide data to understand hepatitis B virus prophylaxis and reactivation outcomes in patients receiving rituximab. Medicine (United States), 96(13). doi: 10.1097/MD.0000000000006528. UCSF: Retrieved from: http://www.escholarship.org/uc/item/4jr7d3h8
Medicine

Supplemental Digital Content is available in the text
Hepatitis B virus (HBV) reactivation in the setting of rituximab use is a potentially fatal but preventable safety event. The rate of HBV screening and proportion of patients at risk who rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c44980880918ca315c8f702f4782fa
https://doi.org/10.1097/md.0000000000006528

B4-5: Neighborhood Deprivation and Telomere Length: Preliminary Findings from the Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH)

Autor: Rachel A. Whitmer, Charles P. Quesenberry, Sarah Rowell, Jun Shan, Lawrence Walter, Mark N. Kvale, Marianne Sadler, Dilrini K. Ranatunga, Kyle Lapham, Dana Ludwig, Stephen K. Van Den Eeden

Background/Aims Shortened telomeres have been associated with numerous adverse health outcomes. In addition, a number of environmental or external exposures, including smoking, air pollution and stress, have been reported to be associated with short

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be6df5ae7ae5063e8cb019b3f8b314f
https://europepmc.org/articles/PMC3788539/