Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Dana L. Swenson"'
Homologous and heterologous protection of nonhuman primates by Ebola and Sudan virus-like particles.
Autor:
Kelly L Warfield, John M Dye, Jay B Wells, Robert C Unfer, Frederick W Holtsberg, Sergey Shulenin, Hong Vu, Dana L Swenson, Sina Bavari, M Javad Aman
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118881 (2015)
Filoviruses cause hemorrhagic fever resulting in significant morbidity and mortality in humans. Several vaccine platforms that include multiple virus-vectored approaches and virus-like particles (VLPs) have shown efficacy in nonhuman primates. Previo
Externí odkaz:
https://doaj.org/article/4be6a58712434a6db06a646cdaa6bcab
Autor:
Hong Vu, Gary Wong, Frederick W. Holtsberg, M. Javad Aman, Sergey Shulenin, Stephanie Sproule, Gaya K. Amarasinghe, Daisy W. Leung, Katie A. Howell, Kelly L. Warfield, Joan B. Geisbert, Dana L. Swenson, Gary P. Kobinger, Sina Bavari, Thomas W. Geisbert
Publikováno v:
The Journal of Infectious Diseases. 218:S553-S564
BACKGROUND: Several vaccine platforms have been successfully evaluated for prevention of Ebola virus (EBOV) disease (EVD) in nonhuman primates and humans. Despite remarkable efficacy by multiple vaccines, the immunological correlates of protection ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7aaba9f4a74dc57b2a05ca471faafd0
https://doi.org/10.1093/infdis/jiy316
https://doi.org/10.1093/infdis/jiy316
Autor:
Kelly L Warfield, Dana L Swenson, Gene G Olinger, Donald K Nichols, William D Pratt, Robert Blouch, David A Stein, M Javad Aman, Patrick L Iversen, Sina Bavari
Publikováno v:
PLoS Pathogens, Vol 2, Iss 1, p e1 (2006)
The filoviruses Marburg virus and Ebola virus (EBOV) quickly outpace host immune responses and cause hemorrhagic fever, resulting in case fatality rates as high as 90% in humans and nearly 100% in nonhuman primates. The development of an effective th
Externí odkaz:
https://doaj.org/article/d16e2b66f8714509aaf4c08fc04308f7
Autor:
Kelly L. Warfield, Peter Sazani, Jay S. Charleston, Sina Bavari, Edward M. Kaye, Travis K. Warren, Alison E. Heald, Jay B. Saoud, Michael Wong, Lisa S. Welch, Jay Wells, Dana L. Swenson, Mohamed Al-Ibrahim, Patrick L. Iversen, Diane Berry
Publikováno v:
New England Journal of Medicine. 373:339-348
AVI-7288 is a phosphorodiamidate morpholino oligomer with positive charges that targets the viral messenger RNA that encodes Marburg virus (MARV) nucleoprotein. Its safety in humans is undetermined.We assessed the efficacy of AVI-7288 in a series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6c7ea21350d0d69ee05179a559b794
https://doi.org/10.1056/nejmoa1410345
https://doi.org/10.1056/nejmoa1410345
Autor:
Travis K. Warren, Dana L. Swenson, Nicole L. Garza, Jay Wells, Dan V. Mourich, Lian Dong, Kelly L. Warfield, Kelly S Donner, Donald K. Nichols, Patrick L. Iversen, Stacy Crumley, Sina Bavari, Sean A. Van Tongeren
Publikováno v:
Nature Medicine. 16:991-994
Currently, no vaccines or therapeutics are licensed to counter Ebola or Marburg viruses, highly pathogenic filoviruses that are causative agents of viral hemorrhagic fever. Here we show that administration of positively charged phosphorodiamidate mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130620075065a36d1890d9269df5c33f
https://doi.org/10.1038/nm.2202
https://doi.org/10.1038/nm.2202
Publikováno v:
Expert Review of Vaccines. 7:417-429
Virus-like particle (VLP)-based vaccines have the advantage of being morphologically and antigenically similar to the live virus from which they are derived. Expression of the glycoprotein and VP40 matrix protein from Lake Victoria marburgvirus (MARV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6503866745c2faef69219852c40b6b
https://doi.org/10.1586/14760584.7.4.417
https://doi.org/10.1586/14760584.7.4.417
Autor:
John Y. Dong, William D. Pratt, Danher Wang, Kelly L. Warfield, Dana L. Swenson, Jan Woraratanadharm, Min Luo, David H. Holman
Publikováno v:
Clinical and Vaccine Immunology. 15:460-467
Filoviruses (Ebola and Marburg viruses) are among the deadliest viruses known to mankind, with mortality rates nearing 90%. These pathogens are highly infectious through contact with infected body fluids and can be easily aerosolized. Additionally, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffc7206580b63078429c51c0a7fa1274
https://doi.org/10.1128/cvi.00431-07
https://doi.org/10.1128/cvi.00431-07
Autor:
Sofi Ibrahim, M. Javad Aman, Warren V. Kalina, Mathias Viard, Yossef Raviv, Kelly L. Warfield, Gene G. Olinger, Xiaoli Chi, Dana L. Swenson, Robert Blumenthal, Mohamed Aitichou, Sina Bavari
Publikováno v:
The Journal of Infectious Diseases. 196:S276-S283
Current methods for inactivating filoviruses are limited to high doses of irradiation or formalin treatment, which may cause structural perturbations that are reflected by poor immunogenicity. In this report, we describe a novel inactivation techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf6029dadb3dbe910c4c58013abd31e
https://doi.org/10.1086/520605
https://doi.org/10.1086/520605
Autor:
Frederick W. Holtsberg, M. Javad Aman, Sergey Shulenin, Sina Bavari, Robert C. Unfer, Dana L. Swenson, John M. Dye, Hong Vu, Kelly L. Warfield, Jay Wells
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118881 (2015)
PLoS ONE
PLoS ONE
Filoviruses cause hemorrhagic fever resulting in significant morbidity and mortality in humans. Several vaccine platforms that include multiple virus-vectored approaches and virus-like particles (VLPs) have shown efficacy in nonhuman primates. Previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c6809874e0f47f52a60ac8f6cd0834
https://doaj.org/article/4be6a58712434a6db06a646cdaa6bcab
https://doaj.org/article/4be6a58712434a6db06a646cdaa6bcab