Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Dana L. Baker"'
Autor:
Dana L. Baker, Chris Harp, H-Christian von Büdingen, Teresa Davancaze, Ann Herman, Saloumeh K Fischer, Michael J. Townsend, Robert Hendricks, Jochen Brumm
Publikováno v:
Bioanalysis. 11:1405-1418
Background: Neurofilament light (NfL) chain is an established cerebrospinal fluid (CSF) biomarker for neuroaxonal injury. The highly sensitive Quanterix Simoa™ platform is evaluated for NfL measurement in both CSF and blood. There is a need to link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c506f6575e4067874de04892cb0224d
https://doi.org/10.4155/bio-2019-0163
https://doi.org/10.4155/bio-2019-0163
Publikováno v:
The AAPS Journal. 18:115-123
Omalizumab (Xolair®) is a recombinant humanized monoclonal antibody that selectively binds to human immunoglobulin E (IgE). Omalizumab is used to treat IgE-mediated diseases such as chronic idiopathic urticaria (CIU) and moderate to severe allergic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdb72f94c2ded0200c10d1aa6da7f77
https://doi.org/10.1208/s12248-015-9821-x
https://doi.org/10.1208/s12248-015-9821-x
Autor:
Alvydas Mikulskis, David Yeung, Dana L. Baker, Saloumeh K Fischer, Mark Dysinger, Alison Joyce, Andreas Jeromin, Allison Given Chunyk, Rosemary Lawrence-Henderson
Publikováno v:
The AAPS Journal. 20
An in-depth evaluation of the Quanterix© Simoa™ platform was undertaken by scientists from the AAPS Emerging Technologies Focus Group to determine the overall performance of the technology as well as provide guidance to future users. In order to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a162b80e3ec68f5443c0c4a52cbc1091
https://doi.org/10.1208/s12248-017-0156-7
https://doi.org/10.1208/s12248-017-0156-7
Autor:
Paul Auger, Stephen P. Schauer, Andrea Pfeifer, Peter Liu, Maria Pihlgren, Kristin R. Wildsmith, Andreas Muhs, Marcel P. van der Brug, Julie Lee, Hsu-Hsin Chen, Oskar Adolfsson, Thomas G. Beach, Dana L. Baker, Akash Datwani
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e286895d32ed2be225d8be0ea635d77a
https://doi.org/10.1016/j.jalz.2017.06.1964
https://doi.org/10.1016/j.jalz.2017.06.1964
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 302:1023-1030
N-Methyl-D-aspartate (NMDA) receptors are calcium-permeable glutamate receptors that play putative roles in learning, memory, and excitotoxicity. NMDA receptor-mediated calcium entry can activate the calcium-dependent protease calpain, leading to sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae395c33e803c36876adac052a0e7822
https://doi.org/10.1124/jpet.102.036962
https://doi.org/10.1124/jpet.102.036962
Publikováno v:
Current medical research and opinion. 30(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e839e4425adc7094450ea5b49c51d250
https://pubmed.ncbi.nlm.nih.gov/24914579
https://pubmed.ncbi.nlm.nih.gov/24914579
Publikováno v:
The AAPS journal. 16(4)
Data generated using various immunoassay methods are an integral part of the development of protein therapeutics. These assays are used in clinical and preclinical studies to establish the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e566ef4f6872d0191ca258bb7c60a33a
https://pubmed.ncbi.nlm.nih.gov/24752719
https://pubmed.ncbi.nlm.nih.gov/24752719
Publikováno v:
Clinical and Experimental Immunology. 113:289-296
SUMMARYRecombinant human deoxyribonuclease I (rhDNase) may be an effective therapeutic for the treatment of systemic lupus erythematosus (SLE). The pharmacodynamics of rhDNase in serum was investigated using two activity assays: one based on hydrolys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa95f6b1c626ccf92e6cba16ffadd32a
https://doi.org/10.1046/j.1365-2249.1998.00647.x
https://doi.org/10.1046/j.1365-2249.1998.00647.x
Autor:
Tony H. Dodge, Robert A. Lazarus, Dana L. Baker, Clark Q. Pan, Dominick Sinicropi, William S. Prince
Publikováno v:
Journal of Biological Chemistry. 273:18374-18381
The ability of recombinant human DNase I (DNase I) to degrade DNA to lower molecular weight fragments is the basis for its therapeutic use in cystic fibrosis (CF) patients and its potential use as a treatment for systemic lupus erythematosus (SLE). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a10f9835036995e3cc3785dc37e1ec2
https://doi.org/10.1074/jbc.273.29.18374
https://doi.org/10.1074/jbc.273.29.18374
Autor:
Eric Stefanich, Deborah L. Mortensen, Wendy S. Putnam, Kristin Wallace, Saloumeh Kadkhodayan-Fischer, Paul J. Fielder, Thomas Gelzleichter, Jenny Jiang, Saileta Prabhu, Dana L. Baker, Suhasini Iyer
Modulating the binding affinities to IgE or changing the FcγR binding properties of anti-IgE antibodies offers an opportunity to enhance the therapeutic potential of anti-IgE antibodies, but the influence of increased affinity to IgE or reduced Fc e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ca34912b3cf9479a187310d4a2e2e6
https://europepmc.org/articles/PMC3502239/
https://europepmc.org/articles/PMC3502239/
