Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Dana L Miller"'
Autor:
Kelsie RS Doering, Xuanjin Cheng, Luke Milburn, Ramesh Ratnappan, Arjumand Ghazi, Dana L Miller, Stefan Taubert
Publikováno v:
eLife, Vol 11 (2022)
The response to insufficient oxygen (hypoxia) is orchestrated by the conserved hypoxia-inducible factor (HIF). However, HIF-independent hypoxia response pathways exist that act in parallel with HIF to mediate the physiological hypoxia response. Here,
Externí odkaz:
https://doaj.org/article/2152140e667142a9ab333b63c4473db0
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008242 (2019)
Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death. We have shown that specific hypoxic conditions disrupt protein homeostasis in C. elegans, leading to protein aggregation and proteotoxic
Externí odkaz:
https://doaj.org/article/0dab65d95a8e473f982e9d228191df5a
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25476 (2011)
Hydrogen sulfide (H₂S) has dramatic physiological effects on animals that are associated with improved survival. C. elegans grown in H₂S are long-lived and thermotolerant. To identify mechanisms by which adaptation to H₂S effects physiological
Externí odkaz:
https://doaj.org/article/c8d778846b01407c85aa43df054dd9f1
Autor:
Michael Petrascheck, Dana L. Miller
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
Independent reproducibility is essential to the generation of scientific knowledge. Optimizing experimental protocols to ensure reproducibility is an important aspect of scientific work. Genetic or pharmacological lifespan extensions are generally sm
Externí odkaz:
https://doaj.org/article/b10f5f8e333640deadda572cc34f0727
Publikováno v:
Genetics. 213:481-490
Hydrogen sulfide (H2S) is an endogenously produced signaling molecule that can be cytoprotective, especially in conditions of ischemia/reperfusion injury. However, H2S is also toxic, and unregulated accumulation or exposure to environmental H2S can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ee6e444c5a2802f80df11a5b4da67e6
https://doi.org/10.1534/genetics.119.302326
https://doi.org/10.1534/genetics.119.302326
Autor:
Kelsie R S, Doering, Xuanjin, Cheng, Luke, Milburn, Ramesh, Ratnappan, Arjumand, Ghazi, Dana L, Miller, Stefan, Taubert
Publikováno v:
eLife. 11
The response to insufficient oxygen (hypoxia) is orchestrated by the conserved hypoxia-inducible factor (HIF). However, HIF-independent hypoxia response pathways exist that act in parallel with HIF to mediate the physiological hypoxia response. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6f7137fcbec0f46d0773c7990860479
https://pubmed.ncbi.nlm.nih.gov/35285794
https://pubmed.ncbi.nlm.nih.gov/35285794
Autor:
Dana L. Miller, Ramesh Ratnappan, Kelsie R. S. Doering, Xuanjin Cheng, Arjumand Ghazi, Stefan Taubert, Luke J. Milburn
The response to insufficient oxygen (hypoxia) is orchestrated by the conserved Hypoxia-Inducible Factor (HIF). However, HIF-independent hypoxia response pathways exist that act in parallel to HIF to mediate the physiological hypoxia response. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66682f81a30f741ecab5ce3522e56f06
https://doi.org/10.1101/2021.02.24.432575
https://doi.org/10.1101/2021.02.24.432575
Autor:
Nicole N Iranon, Dana L. Miller
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
The ability to sense and respond to stressful conditions is essential to maintain organismal homeostasis. It has long been recognized that stress response factors that improve survival in changing conditions can also influence longevity. In this revi
Externí odkaz:
https://doaj.org/article/4af96a3e16c24fc4b28a5ba99e1a15c8
Autor:
Irini Topalidou, Dana L. Miller
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 11, Pp 3699-3704 (2017)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Hydrogen sulfide is common in the environment, and is also endogenously produced by animal cells. Although hydrogen sulfide is often toxic, exposure to low levels of hydrogen sulfide improves outcomes in a variety of mammalian models of ischemia-repe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc496b8ec3174fbf34d970198e3825cc
http://g3journal.org/lookup/doi/10.1534/g3.117.300146
http://g3journal.org/lookup/doi/10.1534/g3.117.300146