Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Dana K. Mitchell"'
Autor:
Evan DuBose, Samantha M. Bevill, Dana K. Mitchell, Noah Sciaky, Brian T. Golitz, Shelley A. H. Dixon, Steven D. Rhodes, James E. Bear, Gary L. Johnson, Steven P. Angus
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionApproximately 50% of melanomas harbor an activating BRAFV600E mutation. Standard of care involves a combination of inhibitors targeting mutant BRAF and MEK1/2, the substrate for BRAF in the MAPK pathway. PTEN loss-of-function mutations oc
Externí odkaz:
https://doaj.org/article/858ea32fd4334cda9da5e4e67522fa6f
Autor:
Silpa Gampala, Hye-ran Moon, Randall Wireman, Jacqueline Peil, Sonia Kiran, Dana K. Mitchell, Kylee Brewster, Henry Mang, Andi Masters, Christine Bach, Whitney Smith-Kinnamen, Emma H. Doud, Ratan Rai, Amber L. Mosley, Sara K. Quinney, D. Wade Clapp, Chafiq Hamdouchi, James Wikel, Chi Zhang, Bumsoo Han, Millie M. Georgiadis, Mark R. Kelley, Melissa L. Fishel
Publikováno v:
Pharmacological Research, Vol 201, Iss , Pp 107092- (2024)
AP endonuclease-1/Redox factor-1 (APE1/Ref-1 or Ref-1) is a multifunctional protein that is overexpressed in most aggressive cancers and impacts various cancer cell signaling pathways. Ref-1′s redox activity plays a significant role in activating t
Externí odkaz:
https://doaj.org/article/aab80d4f3cdf4047a242a19cd4eadd78
Autor:
Ka‐Kui Chan, Zahi Abdul‐Sater, Aditya Sheth, Dana K. Mitchell, Richa Sharma, Donna M. Edwards, Ying He, Grzegorz Nalepa, Steven D. Rhodes, D. Wade Clapp, Elizabeth A. Sierra Potchanant
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 860-884 (2022)
The Fanconi anemia (FA) pathway safeguards genomic stability through cell cycle regulation and DNA damage repair. The canonical tumor suppressive role of FA proteins in the repair of DNA damage during interphase is well established, but their functio
Externí odkaz:
https://doaj.org/article/af81c065551f42e1919675d6c2a442a5
Autor:
Matthew D. Durbin, Lindsey R. Helvaty, Ming Li, William Border, Sara Fitzgerald-Butt, Vidu Garg, Gabrielle C. Geddes, Benjamin M. Helm, Seema R. Lalani, Kim L. McBride, Alexis McEntire, Dana K. Mitchell, Chaya N. Murali, Stephanie B. Wechsler, Benjamin J. Landis, Stephanie M. Ware
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100814- (2023)
Purpose: For patients with congenital heart disease (CHD), the most common birth defect, genetic evaluation is not universally accepted, and current practices are anecdotal. Here, we analyzed genetic evaluation practices across centers, determined di
Externí odkaz:
https://doaj.org/article/6e7126e01ae843229c6b557e44a82b1c
Autor:
Donna M. Edwards, Dana K. Mitchell, Zahi Abdul-Sater, Ka-Kui Chan, Zejin Sun, Aditya Sheth, Ying He, Li Jiang, Jin Yuan, Richa Sharma, Magdalena Czader, Pei-Ju Chin, Yie Liu, Guillermo de Cárcer, Grzegorz Nalepa, Hal E. Broxmeyer, D. Wade Clapp, Elizabeth A. Sierra Potchanant
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Fanconi anemia (FA) is a disease of genomic instability and cancer. In addition to DNA damage repair, FA pathway proteins are now known to be critical for maintaining faithful chromosome segregation during mitosis. While impaired DNA damage repair ha
Externí odkaz:
https://doaj.org/article/3f11e067632b4f1cb8c3aaa365e91a9e
Autor:
Kéyana Foster, Dana K. Mitchell, Alyssa Flint, Brooke Rodriguez, Henry Mang, Chris Davis, Steven P. Angus, D. Wade Clapp, Charles Yates
Publikováno v:
Proceedings of IMPRS. 5
Neurofibromatosis type 2 (NF2) is an autosomal dominant cancer predisposition syndrome characterized by the development of bilateral vestibular (VS) and spinal schwannomas secondary to loss of heterozygosity of NF2 in Schwann cells or their precursor
Autor:
Matthew D. Durbin, Korre Fairman, Lindsey R. Helvaty, Manyan Huang, Ming Li, Daniel Abreu, Gabrielle C. Geddes, Benjamin M. Helm, Benjamin J. Landis, Alexis McEntire, Dana K. Mitchell, Stephanie M. Ware
Publikováno v:
The Journal of Pediatrics. :113495
Autor:
Julie A, Mund, SuJung, Park, Abbi E, Smith, Yongzheng, He, Li, Jiang, Eric, Hawley, Michelle J, Roberson, Dana K, Mitchell, Mohannad, Abu-Sultanah, Jin, Yuan, Waylan K, Bessler, George, Sandusky, Shi, Chen, Chi, Zhang, Steven D, Rhodes, D Wade, Clapp
Publikováno v:
J Biol Chem
Neurofibromatosis type 1 (NF1) is a common cancer predisposition syndrome caused by mutations in the NF1 tumor suppressor gene. NF1 encodes neurofibromin, a GTPase-activating protein for RAS proto-oncogene GTPase (RAS). Plexiform neurofibromas are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3131f30c3862db58c27a5ea37caee2d0
https://europepmc.org/articles/PMC7667969/
https://europepmc.org/articles/PMC7667969/