Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dana K Shaw"'
Autor:
Xiaowei Wang, Dana K Shaw, Holly L Hammond, Fayyaz S Sutterwala, Manira Rayamajhi, Kari Ann Shirey, Darren J Perkins, Joseph V Bonventre, Thangam S Velayutham, Sean M Evans, Kyle G Rodino, Lauren VieBrock, Karen M Scanlon, Nicholas H Carbonetti, Jason A Carlyon, Edward A Miao, Jere W McBride, Michail Kotsyfakis, Joao H F Pedra
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005803 (2016)
Rickettsial agents are sensed by pattern recognition receptors but lack pathogen-associated molecular patterns commonly observed in facultative intracellular bacteria. Due to these molecular features, the order Rickettsiales can be used to uncover br
Externí odkaz:
https://doaj.org/article/130f8b62410e47cdafb35a596bcc86c1
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162501 (2016)
Borrelia burgdorferi is a spirochetal bacterium transmitted by the Ixodes tick that causes Lyme disease in humans due to its ability to evade the host immune response and disseminate to multiple immunoprotective tissues. The pathogen undergoes dynami
Externí odkaz:
https://doaj.org/article/714d758d84684d699067cab506a3cb21
Autor:
L. Rainer Butler, Nisha Singh, Liron Marnin, Luisa M. Valencia, Anya J. O’Neal, Francy E. Cabrera Paz, Dana K. Shaw, Adela S. Oliva Chavez, Joao H. F. Pedra
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background The blacklegged tick, Ixodes scapularis, transmits most vector-borne diseases in the US. It vectors seven pathogens of public health relevance, including the emerging human pathogen Anaplasma phagocytophilum. Nevertheless, it rema
Externí odkaz:
https://doaj.org/article/05e56b34e7ea41e7b9fa76b671ae63b2
Autor:
Jason M. Park, Brittany M. Genera, Deirdre Fahy, Kyle T. Swallow, Curtis M. Nelson, Jonathan D. Oliver, Dana K. Shaw, Ulrike G. Munderloh, Kelly A. Brayton
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Pathogens must adapt to disparate environments in permissive host species, a feat that is especially pronounced for vector-borne microbes, which transition between vertebrate hosts and arthropod vectors to complete their lifecycles. Most kno
Externí odkaz:
https://doaj.org/article/5791de239c8848dda4561cb257461ef9
Autor:
Kristin L. Rosche, Joanna Hurtado, Elis A. Fisk, Kaylee A. Vosbigian, Ashley L. Warren, Lindsay C. Sidak-Loftis, Sarah J. Wright, Elisabeth Ramirez-Zepp, Jason M. Park, Dana K. Shaw
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT A crucial phase in the life cycle of tick-borne pathogens is the time spent colonizing and persisting within the arthropod. Tick immunity is emerging as a key force shaping how transmissible pathogens interact with the vector. How pathogens
Externí odkaz:
https://doaj.org/article/ab818690846f407d9a0cf16c91342663
Autor:
Lindsay C. Sidak-Loftis, Kristin L. Rosche, Natasha Pence, Jessica K. Ujczo, Joanna Hurtado, Elis A. Fisk, Alan G. Goodman, Susan M. Noh, John W. Peters, Dana K. Shaw
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/861ceabc631346959f2a9f9987b5129f
Autor:
Lindsay C. Sidak-Loftis, Kristin L. Rosche, Natasha Pence, Jessica K. Ujczo, Joanna Hurtado, Elis A. Fisk, Alan G. Goodman, Susan M. Noh, John W. Peters, Dana K. Shaw
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT The insect immune deficiency (IMD) pathway is a defense mechanism that senses and responds to Gram-negative bacteria. Ticks lack genes encoding upstream components that initiate the IMD pathway. Despite this deficiency, core signaling molecu
Externí odkaz:
https://doaj.org/article/b82ad04b1473414594ba604835926d16
Autor:
Anya J. O’Neal, Nisha Singh, Agustin Rolandelli, Hanna J. Laukaitis, Xiaowei Wang, Dana K. Shaw, Brianna D. Young, Sukanya Narasimhan, Shraboni Dutta, Greg A. Snyder, Sourabh Samaddar, Liron Marnin, L. Rainer Butler, M. Tays Mendes, Francy E. Cabrera Paz, Luisa M. Valencia, Eric J. Sundberg, Erol Fikrig, Utpal Pal, David J. Weber, Joao H. F. Pedra
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elici
Autor:
Muna Salem M. Solyman, Jessica Ujczo, Kelly A. Brayton, Dana K. Shaw, David A. Schneider, Susan M. Noh
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3941
Anaplasma spp. are obligate intracellular, tick-borne, bacterial pathogens that cause bovine and human anaplasmosis. We lack tools to prevent these diseases in part due to major knowledge gaps in our fundamental understanding of the tick–pathogen i
Autor:
Muna Salem M, Solyman, Jessica, Ujczo, Kelly A, Brayton, Dana K, Shaw, David A, Schneider, Susan M, Noh
Publikováno v:
International journal of molecular sciences. 23(7)