Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Dana K Merriman"'
Autor:
Viktor V Feketa, Yury A Nikolaev, Dana K Merriman, Sviatoslav N Bagriantsev, Elena O Gracheva
Publikováno v:
eLife, Vol 9 (2020)
Most mammals maintain their body temperature around 37°C, whereas in hibernators it can approach 0°C without triggering a thermogenic response. The remarkable plasticity of the thermoregulatory system allowed mammals to thrive in variable environme
Externí odkaz:
https://doaj.org/article/595385e2045f4abfbdcfad386e5d816b
Autor:
Sarah M. Mohr, Rafael Dai Pra, Maryann P. Platt, Viktor V. Feketa, Marya Shanabrough, Luis Varela, Ashley Kristant, Haoran Cao, Dana K. Merriman, Tamas L. Horvath, Sviatoslav N. Bagriantsev, Elena O. Gracheva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Mammalian hibernators survive prolonged periods of cold and resource scarcity by temporarily modulating normal physiological functions, but the mechanisms underlying these adaptations are poorly understood. The hibernation cycle of thirteen-
Externí odkaz:
https://doaj.org/article/85482d9133b24981b7be3db42e371392
Autor:
Eva Andres-Mateos, Rebeca Mejias, Arshia Soleimani, Brian M Lin, Tyesha N Burks, Ruth Marx, Benjamin Lin, Richard C Zellars, Yonggang Zhang, David L Huso, Tom G Marr, Leslie A Leinwand, Dana K Merriman, Ronald D Cohn
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48884 (2012)
Skeletal muscle atrophy can occur as a consequence of immobilization and/or starvation in the majority of vertebrates studied. In contrast, hibernating mammals are protected against the loss of muscle mass despite long periods of inactivity and lack
Externí odkaz:
https://doaj.org/article/ef4465b7d4724246ad44a972e47f3a2b
Autor:
Tylor R. Lewis, Sebastien Phan, Keun-Young Kim, Isha Jha, Carson M. Castillo, Jin-Dong Ding, Benjamin S. Sajdak, Dana K. Merriman, Mark H. Ellisman, Vadim Y. Arshavsky
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 12 (2022)
Externí odkaz:
https://doaj.org/article/877868f0b3154fcf8cf59f39ff07406b
Autor:
Vanessa Matos-Cruz, Eve R. Schneider, Marco Mastrotto, Dana K. Merriman, Sviatoslav N. Bagriantsev, Elena O. Gracheva
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3329-3337 (2017)
Summary: Thirteen-lined ground squirrels and Syrian hamsters are known for their ability to withstand cold during hibernation. We found that hibernators exhibit cold tolerance even in the active state. Imaging and electrophysiology of squirrel somato
Externí odkaz:
https://doaj.org/article/bb9b490c24ae4fc4a0ec9c7cdb8c28a6
Autor:
Sarah M. Mohr, Rafael Dai Pra, Maryann P. Platt, Viktor V. Feketa, Marya Shanabrough, Luis Varela, Ashley Kristant, Haoran Cao, Dana K. Merriman, Tamas L. Horvath, Sviatoslav N. Bagriantsev, Elena O. Gracheva
Mammalian hibernators survive prolonged periods of cold and resource scarcity by temporarily modulating normal physiological functions, but the mechanisms underlying these adaptations are poorly understood. The hibernation cycle of thirteen-lined gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcaf6e2727a396b7ec7379232e2e3d98
https://doi.org/10.1101/2023.03.15.532843
https://doi.org/10.1101/2023.03.15.532843
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss, Pp 96-106 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Intravitreal injection is the most widely used injection technique for ocular gene delivery. However, vector diffusion is attenuated by physical barriers and neutralizing antibodies in the vitreous. The 13-lined ground squirrel (13-LGS), as in humans
Autor:
Susan Freling, Dana K. Merriman, Robert F. Cooper, Joseph Carroll, Mina Gaffney, Alexander E Salmon, Ching T Yu, Jenna Cava, Hannah M Follett
Publikováno v:
Exp Biol Med (Maywood)
In vivo images of human cone photoreceptors have been shown to vary in their reflectance both spatially and temporally. While it is generally accepted that the unique anatomy and physiology of the photoreceptors themselves drives this behavior, the e
PurposeThe cone-dominant, 13-lined ground squirrel (13-LGS) retina mimics the human foveal region but retinal development in this useful rodent species has not been reported. Here, the embryonic and postnatal development of the 13-LGS retina was stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e9ee633dcb4192dfacf5fe73fe04353
https://doi.org/10.1101/2021.12.25.474168
https://doi.org/10.1101/2021.12.25.474168
Autor:
Rafael Dai Pra, Sarah M. Mohr, Dana K. Merriman, Sviatoslav N. Bagriantsev, Elena O. Gracheva
Publikováno v:
Current biology : CB. 32(8)
Adequate nutrition is essential for normal reproductive function, which is vital for species to survive. In humans and other mammals, starvation and undernutrition deplete fat reserves and cause weight loss, attenuating the function of the reproducti