Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dana Ishay-Ronen"'
Autor:
Neta Bar-Hai, Rakefet Ben-Yishay, Sheli Arbili-Yarhi, Naama Herman, Vered Avidan-Noy, Tehillah Menes, Aiham Mansour, Fahim Awwad, Nora Balint-Lahat, Gil Goldinger, Goni Hout-Siloni, Mohammad Adileh, Raanan Berger, Dana Ishay-Ronen
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Cellular plasticity is enhanced by dedifferentiation processes such as epithelial-mesenchymal transition (EMT). The dynamic and transient nature of EMT-like processes challenges the investigation of cell plasticity in patient-derived breast cancer mo
Externí odkaz:
https://doaj.org/article/80c42a7fdd9d4dd1a8f30d553838a539
Autor:
Rakefet Ben-Yishay, Opher Globus, Nora Balint-Lahat, Sheli Arbili-Yarhi, Neta Bar-Hai, Vered Bar, Sara Aharon, Anna Kosenko, Adi Zundelevich, Raanan Berger, Dana Ishay-Ronen
Publikováno v:
Cells, Vol 13, Iss 17, p 1506 (2024)
Epithelial-to-mesenchymal transition (EMT) plays a major role in breast cancer progression and the development of drug resistance. We have previously demonstrated a trans-differentiation therapeutic approach targeting invasive dedifferentiated cancer
Externí odkaz:
https://doaj.org/article/c330496992df471197afa20b6a4dc4ea
Autor:
Jonathan M Matthews, Brooke Schuster, Sara Saheb Kashaf, Ping Liu, Rakefet Ben-Yishay, Dana Ishay-Ronen, Evgeny Izumchenko, Le Shen, Christopher R Weber, Margaret Bielski, Sonia S Kupfer, Mustafa Bilgic, Andrey Rzhetsky, Savaş Tay
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010584 (2022)
Organoids have immense potential as ex vivo disease models for drug discovery and personalized drug screening. Dynamic changes in individual organoid morphology, number, and size can indicate important drug responses. However, these metrics are diffi
Externí odkaz:
https://doaj.org/article/566dc2ed98c6459aa44fb593a7fd1f73
Autor:
Neta Bar-Hai, Dana Ishay-Ronen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer is a systemic heterogeneous disease that can undergo several rounds of latency and activation. Tumor progression evolves by increasing diversity, adaptation to signals from the microenvironment and escape mechanisms from therapy. These dynamic
Externí odkaz:
https://doaj.org/article/1e8205f0c7294ce58e706f6552f55fcb
Autor:
Avital Schwed-Gross, Hila Hamiel, Gabriel P. Faber, Mor Angel, Rakefet Ben-Yishay, Jennifer I. C. Benichou, Dana Ishay-Ronen, Yaron Shav-Tal
Publikováno v:
Journal of Cell Science. 135
Stress granules (SGs) can assemble in cancer cells upon chemotoxic stress. Glucocorticoids function during stress responses and are administered with chemotherapies. The roles of glucocorticoids in SG assembly and disassembly pathways are unknown. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10806dc0bf13d5b079a6abda37124539
https://doi.org/10.1242/jcs.259629
https://doi.org/10.1242/jcs.259629
Autor:
Jonathan Matthews, Brooke Schuster, Sara Saheb Kashaf, Ping Liu, Rakefet Ben-Yishay, Dana Ishay-Ronen, Le Shen, Christopher Weber, Margaret Bielski, Sonia S. Kupfer, Mustafa Bilgic, Andrey Rzhetsky, Savaş Tay
Organoids have immense potential as ex vivo disease models for drug discovery and personalized drug screening. Dynamic changes in individual organoid morphology, number, and size can indicate important drug responses, however these metrics are diffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35e9633994af7d542d8f42134ef759ae
https://doi.org/10.1101/2022.01.13.476248
https://doi.org/10.1101/2022.01.13.476248
Autor:
Dana Ishay-Ronen, Gerhard Christofori, Herbert Levine, Ayse Nihan Kilinc, Mohit Kumar Jolly, Helena Antoniadis, Huseyin Birogul, Ravi Kiran Reddy Kalathur, Jason T. George, Nami Sugiyama
Publikováno v:
Oncogene. 39:1498-1513
An epithelial-mesenchymal transition (EMT) represents a basic morphogenetic process of high cell plasticity underlying embryogenesis, wound healing, cancer metastasis and drug resistance. It involves a profound transcriptional and epigenetic reprogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c04590cf0de478d587f45d77965ad91
https://doi.org/10.1038/s41388-019-1081-2
https://doi.org/10.1038/s41388-019-1081-2
Publikováno v:
Cancer Research. 82:5847-5847
Background: Epithelial-mesenchymal transition (EMT) in breast cancer drives tumor invasion, metastasis and drug resistance. BRCA1 mutation carriers have a high risk for developing aggressive basal-like triple-negative breast cancers with EMT characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e60c54d2af127774177f22966ee85cb
https://doi.org/10.1158/1538-7445.am2022-5847
https://doi.org/10.1158/1538-7445.am2022-5847
Autor:
Gerhard Christofori, Dana Ishay-Ronen
Publikováno v:
Cancer research. 79(21)
Cancer is a systemic heterogeneous disease that can undergo several rounds of latency and activation. Malignant tumors evolve through dynamic responses to microenvironmental signals and development of resistance following therapeutic interventions. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb089af79f4f754cde1ea41b1fc0b06b
https://pubmed.ncbi.nlm.nih.gov/31331908
https://pubmed.ncbi.nlm.nih.gov/31331908
Autor:
Maren Diepenbruck, Ravi Kiran Reddy Kalathur, Nami Sugiyama, Stefanie Tiede, Dana Ishay-Ronen, Glenn R. Bantug, Marco Francesco Morini, Christoph Hess, Gerhard Christofori, Junrong Wang, Robert Ivanek
Publikováno v:
Cancer Cell. 35:17-32.e6
Summary Cancer cell plasticity facilitates the development of therapy resistance and malignant progression. De-differentiation processes, such as an epithelial-mesenchymal transition (EMT), are known to enhance cellular plasticity. Here, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0010520fa04d074522cd2fe5442162
https://doi.org/10.1016/j.ccell.2018.12.002
https://doi.org/10.1016/j.ccell.2018.12.002