Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dana Giulian"'
Autor:
Dana Giulian
Publikováno v:
The American Journal of Human Genetics. 65(1):13-18
This work was supported through National Institutes of Health grants NS3400, NS35972, and AG12548; the Temple Discovery from the Alzheimer's Association; and the Baylor Alzheimer's Disease Research Center.
Autor:
Dana Giulian
Publikováno v:
Annals of the New York Academy of Sciences. 835:91-110
Autor:
Yu Min Kuo, Joel B. Kirkpatrick, Jun Li, Donald Tom, Alex E. Roher, Jiahan Yu, Lanny J. Haverkamp, William Karshin, Dana Giulian
Publikováno v:
Scopus-Elsevier
Alzheimer's disease (AD) is found to have striking brain inflammation characterized by clusters of reactive microglia that surround senile plaques. A recent study has shown that microglia placed in contact with isolated plaque fragments release neuro
Publikováno v:
Neurochemistry International. 29:65-76
Thromboxane A2(TxA2) is a potent vasoconstrictor associated with cerebrovascular disease and is thought to be synthesized within tissues of the brain. In order to determine the cellular sources of TxA2 in the central nervous system (CNS), we measured
Publikováno v:
The Journal of Neuroscience. 15:7712-7726
To investigate differences among brain-derived microglia and other classes of immune cells, we compared the morphologies and growth properties of mononuclear phagocytes isolated from tissues of the newborn rat. Scanning EM shows that microglia from p
Publikováno v:
Proceedings of the National Academy of Sciences. 90:2769-2773
Mononuclear phagocytes infected with human immunodeficiency virus 1 (HIV-1) produce soluble factors that kill neurons in culture. To define the molecular events that lead to neuron killing, HIV-1 proteins were tested for the ability to trigger releas
Autor:
Dana Giulian
Publikováno v:
Glia. 7:102-110
Reactive gliosis is a response noted after nearly every type of CNS injury and involves both activated microglia and astroglia. Although many investigators believe that reactive glia in some way regulate the survival of injured neurons, the influence
Publikováno v:
The Journal of Neuroscience. 11:327-336
Oligodendroglia growth factor (OGF) is a 16-kDa soluble protein produced by neuronal cell lines. This factor, when incubated with brain glia in culture, selectively stimulates growth of oligodendroglia, the myelin-producing cells of the CNS. OGF infu
Publikováno v:
The Journal of Cell Biology
The central nervous system produces growth factors that stimulate proliferation of ameboid microglia during embryogenesis and after traumatic injury. Two microglial mitogens (MMs) are recovered from the brain of newborn rat. MM1 has an approximate mo
Autor:
Dana Giulian, Claudia S. Robertson
Publikováno v:
Annals of Neurology. 27:33-42
Transient ischemia to the lumbar and sacral sections of the spinal cord of rabbit leads to a deterioration in neurological function that usually worsens 24 to 48 hours after injury. This decline in movement of the hindlimbs develops simultaneously wi