Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dana Brooke"'
Autor:
Cohn, Dana Brooke.
Thesis (Ph.D.)--University of Nebraska-Lincoln, 2006.
Title from title screen (site viewed on Jan. 23, 2007). PDF text: 141p. : ill. (some col.) ; 2.17Mb. UMI publication number: AAT 3217537. Includes bibliographical references. Also available i
Title from title screen (site viewed on Jan. 23, 2007). PDF text: 141p. : ill. (some col.) ; 2.17Mb. UMI publication number: AAT 3217537. Includes bibliographical references. Also available i
Autor:
Robert J. Behme, Dana Brooke
Publikováno v:
Journal of pharmaceutical sciences. 80(10)
Two polymorphs of carbamazepine that melt at 176 and 189 degrees C and are known to be enantiotropic have been characterized more fully than in previous reports. For the first time, a value for the heat of fusion (29.3 kJ/mol) of the lower melting fo
Publikováno v:
Journal of Pharmaceutical Sciences. 66:553-557
New approximate expressions for the weight fraction undissolved were obtained using the Taylor series expansion. These approximations were tested using simulated data for multisized drug particle populations. The resulting calculations show that: (a)
Autor:
David E. Guttman, Dana Brooke
Publikováno v:
Journal of the American Chemical Society. 90:4964-4972
Autor:
David E. Guttman, Dana Brooke
Publikováno v:
Journal of Pharmaceutical Sciences. 52:941-945
A study was made of what appears to be a charge-transfer interaction that is responsible for the instantaneous generation of a yellow color in aqueous solutions containing nicotinamide and ascorbic acid. Spectral studies were utilized to elucidate so
Autor:
David E. Guttman, Dana Brooke
Publikováno v:
Journal of Pharmaceutical Sciences. 57:1677-1684
The kinetics of reaction of the ester, 3-carbomethoxy-1-methylpyridinium cation (NME), were investigated in the pH region 8.0–9.8, in the absence and presence of the electron donor, 8-chlorotheophyllinate anion (CT). Hydrolysis of the ester was sho
Publikováno v:
Journal of Pharmaceutical Sciences. 68:172-174
A reversed-phase high-performance liquid chromatographic technique is described for the analysis of cyclophosphamide in the presence of its hydrolysis products. The drug was quantified using a UV detector at a low wavelength. A single band was observ
Publikováno v:
Journal of Pharmaceutical Sciences. 65:763-765
Methanesulfonanilides, like soterenol and mesuprine, which are bioisosteric with adrenergic catecholamines, form fluorescent species when subjected to the trihydroxyindole reaction. Presumably, the fluorescence is due to adrenolutin‐like species fo
Publikováno v:
Journal of Pharmaceutical Sciences. 71:1303-1305
Publikováno v:
Journal of pharmaceutical sciences. 74(10)
Gepirone hydrochloride, an investigational anxiolytic drug, was found to have at least three polymorphic forms which melted at 180 degrees C (I), 212 degrees C (II), and 200 degrees C (III). Thermal analytical studies showed that forms I and II were