Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dana Bohan"'
Autor:
Stacia Phillips, Tarun Mishra, Shaubhagya Khadka, Dana Bohan, Constanza E. Espada, Wendy Maury, Li Wu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT N6-methyladenosine (m6A) is a dynamic posttranscriptional RNA modification that plays an important role in determining transcript fate. The functional consequence of m6A deposition is dictated by a group of host proteins that specifically re
Externí odkaz:
https://doaj.org/article/e4ed6ef927db4003a5a01a1371b97a20
Autor:
Camilla Tvedt Ekanger, Fan Zhou, Dana Bohan, Maria Lie Lotsberg, Maria Ramnefjell, Laurence Hoareau, Gro Vatne Røsland, Ning Lu, Marianne Aanerud, Fabian Gärtner, Pirjo Riitta Salminen, Mariann Bentsen, Thomas Halvorsen, Helge Ræder, Lars A. Akslen, Nina Langeland, Rebecca Cox, Wendy Maury, Linda Elin Birkhaug Stuhr, James B. Lorens, Agnete S. T. Engelsen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The ongoing coronavirus disease 2019 (COVID-19) pandemic has led to the initiation of unprecedented research efforts to understand the pathogenesis mediated by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). More knowledge is needed reg
Externí odkaz:
https://doaj.org/article/06230d8f61374086afc8f77f85184e25
Autor:
Dana Bohan, Hanora Van Ert, Natalie Ruggio, Kai J Rogers, Mohammad Badreddine, José A Aguilar Briseño, Jonah M Elliff, Roberth Anthony Rojas Chavez, Boning Gao, Tomasz Stokowy, Eleni Christakou, Petri Kursula, David Micklem, Gro Gausdal, Hillel Haim, John Minna, James B Lorens, Wendy Maury
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1009743 (2021)
Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by SARS-CoV-2 in cells that expres
Externí odkaz:
https://doaj.org/article/263446c892cf4c9fa83fd3b8a0e7c84e
Autor:
Dana Bohan, Wendy Maury
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009899 (2021)
Externí odkaz:
https://doaj.org/article/17452ca571a1426881817b4ab9d32395
Autor:
Kai J Rogers, Bethany Brunton, Laura Mallinger, Dana Bohan, Kristina M Sevcik, Jing Chen, Natalie Ruggio, Wendy Maury
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 12, p e0007819 (2019)
BackgroundEbolavirus (EBOV) outbreaks, while sporadic, cause tremendous morbidity and mortality. No therapeutics or vaccines are currently licensed; however, a vaccine has shown promise in clinical trials. A critical step towards development of effec
Externí odkaz:
https://doaj.org/article/8d762ec8dd8e4e7196bda5352bc885fd
Autor:
Stacia Phillips, Tarun Mishra, Shaubhagya Khadka, Dana Bohan, Constanza E. Espada, Wendy Maury, Li Wu
Publikováno v:
Microbiology Spectrum. 11
Posttranscriptional modification of viral and cellular RNA by N 6 -methyladenosine (m 6 A) plays an important role in regulating the replication of many viruses and the cellular immune response to infection. We therefore sought to define the epitrans
Autor:
Amin Addetia, Luca Piccoli, James Brett Case, Young-Jun Park, Martina Beltramello, Barbara Guarino, Ha Dang, Dora Pinto, Suzanne M. Scheaffer, Kaitlin Sprouse, Jessica Bassi, Chiara Silacci-Fregni, Francesco Muoio, Marco Dini, Lucia Vincenzetti, Rima Acosta, Daisy Johnson, Sambhavi Subramanian, Christian Saliba, Martina Giurdanella, Gloria Lombardo, Giada Leoni, Katja Culap, Carley McAlister, Anushka Rajesh, Exequiel Dellota, Jiayi Zhou, Nisar Farhat, Dana Bohan, Julia Noack, Florian A. Lempp, Elisabetta Cameroni, Bradley Whitener, Olivier Giannini, Alessandro Ceschi, Paolo Ferrari, Alessandra Franzetti-Pellanda, Maira Biggiogero, Christian Garzoni, Stephanie Zappi, Luca Bernasconi, Min Jeong Kim, Gretja Schnell, Nadine Czudnochowski, Nicholas Franko, Jennifer K. Logue, Courtney Yoshiyama, Cameron Stewart, Helen Chu, Michael A. Schmid, Lisa A. Purcell, Gyorgy Snell, Antonio Lanzavecchia, Michael S. Diamond, Davide Corti, David Veesler
Publikováno v:
bioRxiv
Currently circulating SARS-CoV-2 variants acquired convergent mutations at receptor-binding domain (RBD) hot spots1. Their impact on viral infection, transmission, and efficacy of vaccines and therapeutics remains poorly understood. Here, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce29f8388403bbef8bf55f16166bdbea
https://europepmc.org/articles/PMC9882201/
https://europepmc.org/articles/PMC9882201/
N6-methyladenosine (m6A) is a dynamic post-transcriptional RNA modification that plays an important role in determining transcript fate. Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has caused the global pandemic of coronaviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a27037aeecdee17989c150abb0a11155
https://doi.org/10.1101/2022.08.01.502311
https://doi.org/10.1101/2022.08.01.502311
Autor:
Magnus Blø, Austin Rayford, Noëlly Madeleine, Fabian Gärtner, Dana Bohan, Natalie Ruggio, Huiyu Li, Luc Girard, Rolf Brekken, John Minna, Marianne Ånerud, Wendy Maury, Claudia Gorcea-Carson, Gro Gausdal, David R. Micklem, Nigel McCracken
Publikováno v:
Cancer Research. 83:3245-3245
STK11 (LKB1) is a tumor suppressor, and loss-of-function mutations contribute to tumorigenesis. Mutations in the STK11 gene (STK11m) are present in ~ 20% of NSCLCs and are associated with poor response to chemotherapy and immune checkpoint inhibition
Autor:
Changze Han, Michael Pentella, Mohammad Fili, Natalie Ruggio, Guiping Hu, Grant D. Brown, J. Brooks Jackson, Kristina M. Sevcik, Kai J. Rogers, Tom Gallagher, Wendy Maury, Hanora A Van Ert, Nathan Schwery, C. Michael Knudson, Spencer Dempewolf, Anthony Roberth Rojas Chavez, Anna E. Merrill, Devlin Boyt, Dana Bohan, Enya Qing, Hillel Haim
Publikováno v:
Microbiology Spectrum. 10
The spike protein of SARS-CoV-2 is arranged as a trimer on the virus surface, composed of three S1 and three S2 subunits. Infected and vaccinated individuals generate antibodies against spike, which can neutralize the virus. Most antibodies target th