Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dana A. Lynn"'
Autor:
Yijie Geng, Yongfeng Zhao, Lisa Corinna Schuster, Bradley Feng, Dana A. Lynn, Katherine M. Austin, Jason Daniel Stoklosa, Joseph D. Morrison
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1143-1154 (2015)
Chemical biology methods such as high-throughput screening (HTS) and affinity-based target identification can be used to probe biological systems on a biomacromolecule level, providing valuable insights into the molecular mechanisms of those systems.
Externí odkaz:
https://doaj.org/article/b489c61f229d417ebdd9b02b238dfb79
Autor:
Dana A. Lynn, Sean P. Curran, Jessica N. Sowa, Hans M. Dalton, Alexander A. Soukas, Meng C. Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 112:15378-15383
Animals in nature are continually challenged by periods of feast and famine as resources inevitably fluctuate, and must allocate somatic reserves for reproduction to abate evolutionary pressures. We identify an age-dependent lipid homeostasis pathway
Reproduction is essential to perpetuate life. Animals must utilize strategies in order to allocate the necessary resources for the energy-costly process of reproducing. Here, we show that C. elegans with mutation in alh-6, a conserved mitochondrial p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde6ae6a6581e0a0bdfae27f769af72f
https://europepmc.org/articles/PMC6243592/
https://europepmc.org/articles/PMC6243592/
Autor:
Dana A. Lynn, Sean P. Curran
Publikováno v:
Healthy Ageing and Longevity ISBN: 9783319447018
Over the last 25 years it has become evident that single gene mutations can result in remarkable increases in lifespan. Of the gene mutations identified, the most potent at extending life- and healthspan are those that alter the quantity of food inge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::228aab5174d5dea95c285774ff3edfcb
https://doi.org/10.1007/978-3-319-44703-2_17
https://doi.org/10.1007/978-3-319-44703-2_17
Autor:
Sean P. Curran, Dana A. Lynn
Publikováno v:
Worm. 4(3)
Animals must continually assess nutrient availability to develop appropriate strategies for survival and reproductive success. It is no secret that nutritional state plays a large role in both aging and health.(1-7) Appropriate cellular energy usage
Publikováno v:
Nature Communications
Mechanisms that coordinate different metabolic pathways, such as glucose and lipid, have been recognized. However, a potential interaction between amino acid and lipid metabolism remains largely elusive. Here we show that during starvation of Caenorh
Autor:
Joseph D. Morrison, Bradley Feng, Katherine M. Austin, Lisa Corinna Schuster, Yijie Geng, Yongfeng Zhao, Dana A. Lynn, Jason Daniel Stoklosa
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1143-1154 (2015)
Stem Cell Reports
Stem Cell Reports
Summary Chemical biology methods such as high-throughput screening (HTS) and affinity-based target identification can be used to probe biological systems on a biomacromolecule level, providing valuable insights into the molecular mechanisms of those