Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dana Hoffmann"'
Autor:
Michael Stav, Yuri Matatov, Dana Hoffmann, Philip Heesen, Vincent Gliesche, Yair Binyamin, Alexander Ioscovich, Leonid A. Eidelman, Sharon Orbach‐Zinger
Publikováno v:
Acta anaesthesiologica ScandinavicaREFERENCES. 67(1)
Conversion from spinal anaesthesia to general anaesthesia (GA) was shown to be associated with more complications. It has been postulated that spinal injection of a low dose of local anaesthetic is a risk factor. We aimed to discover the rate of conv
Publikováno v:
Current Psychology.
Academic buoyancy describes the ability to successfully overcome and recover from setbacks in an academic context (e.g., a poor grade, motivational dips, stress due to upcoming performance exams). This day-to-day form of academic resilience has recen
Autor:
Satoshi Kitajima, Makoto Shibutani, Gaku Ichihara, Dana Hoffmann, Masayuki Mishima, Akihiko Hirose, Satoshi Furukawa
Publikováno v:
Fundamental Toxicological Sciences. 5:167-170
Autor:
Janani Saikumar, Florin L. Craciun, Amrendra Kumar Ajay, Dana Hoffmann, Steven L. Fabian, Benjamin D. Humphreys, Vishal S. Vaidya, Vanesa Bijol
Publikováno v:
American Journal of Physiology-Renal Physiology. 307:F471-F484
Fibrinogen (Fg) has been implicated in the pathogenesis of several fibrotic disorders by acting as a profibrotic ligand for a variety of cellular surface receptors and by modulating the provisional fibrin matrix formed after injury. We demonstrated i
Publikováno v:
Biomarkers in Medicine. 8:85-94
Aims:To determine whether urinary biomarkers of acute kidney injury can be used to monitor the progression of chronic kidney injury in a rat model of hypertension and obesity. Materials & methods: A suite of novel urinary biomarkers were used to trac
Autor:
Tae-Min Kim, Dana Hoffmann, Sushrut S. Waikar, Victoria Ramirez Gonzalez, Ronald P. Brown, Janani Saikumar, Qin Zhang, Peter J. Park, Vanesa Bijol, Peter L. Goering, Vishal S. Vaidya
Publikováno v:
Toxicological Sciences. 129:256-267
MicroRNAs (miRNAs) are endogenous noncoding RNA molecules that are involved in post-transcriptional gene silencing. Using global miRNA expression profiling, we found miR-21, -155, and 18a to be highly upregulated in rat kidneys following tubular inju
Autor:
Susanne Schroeder, Jean-Pierre Marchandeau, Jean-Charles Gautier, Dana Hoffmann, Angela Mally, Arnd Brandenburg, Eric Boitier, Emmanuelle Com
Publikováno v:
Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, Elsevier, 2012, 258 (1), pp.124-133. ⟨10.1016/j.taap.2011.10.015⟩
Toxicology and Applied Pharmacology, 2012, 258 (1), pp.124-133. ⟨10.1016/j.taap.2011.10.015⟩
Toxicology and Applied Pharmacology, Elsevier, 2012, 258 (1), pp.124-133. ⟨10.1016/j.taap.2011.10.015⟩
Toxicology and Applied Pharmacology, 2012, 258 (1), pp.124-133. ⟨10.1016/j.taap.2011.10.015⟩
Gentamicin is an aminoglycoside antibiotic, which induces renal tubular necrosis in rats. In the context of the European InnoMed PredTox project, transcriptomic and proteomic studies were performed to provide new insights into the molecular mechanism
Autor:
Tae-Min Kim, Dana Hoffmann, Aparna Krishnamoorthy, Amrendra Kumar Ajay, Victoria Ramírez, Gabriela Campanholle, Norma A. Bobadilla, Vishal S. Vaidya, Sushrut S. Waikar
Publikováno v:
Blood. 118:1934-1942
Ischemia/reperfusion (I/R) injury in the kidney is a major cause of acute kidney injury (AKI) in humans and is associated with significantly high mortality. To identify genes that modulate kidney injury and repair, we conducted genome-wide expression
Autor:
Dana Hoffmann, Katja Matheis, Tanja Henzler, Tobias C. Fuchs, Wolfgang Dekant, Philip Hewitt, Angela Mally, Thomas Herget
Publikováno v:
Toxicology. 277:49-58
Several novel urinary kidney biomarkers were recently approved by the US-FDA and EMA for improved detection of nephrotoxicity, but few data regarding their performance are publicly available so far. In this study, we investigated the potential of som
Autor:
Dana Hoffmann, William M. Gallagher, John J. Callanan, Wolfgang Dekant, Heidrun Ellinger-Ziegelbauer, Angela Mally, Philip G. Hewitt, Katja Matheis, Laura Suter, Melanie Adler, Laoighse Mulrane, Michael Fountoulakis
Publikováno v:
Toxicology Letters. 196:1-11
This study was designed to assess the value of a set of potential markers for improved detection of liver injury in preclinical toxicity studies. Male Wistar rats were treated with drug candidates (BAY16, EMD335823, BI-3) that previously failed durin