Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dana, Stenger"'
Autor:
Franziska Blaeschke, Dana Stenger, Antonia Apfelbeck, Bruno L. Cadilha, Mohamed-Reda Benmebarek, Jasmin Mahdawi, Eva Ortner, Mareike Lepenies, Nicola Habjan, Felicitas Rataj, Semjon Willier, Theresa Kaeuferle, Robbie G. Majzner, Dirk H. Busch, Sebastian Kobold, Tobias Feuchtinger
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-6 (2021)
Externí odkaz:
https://doaj.org/article/af275a1b5c7a4ccfad9a71a7c9aa4002
Autor:
Franziska Blaeschke, Eva Ortner, Dana Stenger, Jasmin Mahdawi, Antonia Apfelbeck, Nicola Habjan, Tanja Weißer, Theresa Kaeuferle, Semjon Willier, Sebastian Kobold, Tobias Feuchtinger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Therapeutic targeting of inhibitory checkpoint molecules in combination with chimeric antigen receptor (CAR) T cells is currently investigated in a variety of clinical studies for treatment of hematologic and solid malignancies. However, the impact o
Externí odkaz:
https://doaj.org/article/854adee3aa3543c4b4bbd7ad61959e1a
Autor:
Theresa Kaeuferle, Tanja A Stief, Stefan Canzar, Nayad N Kutlu, Semjon Willier, Dana Stenger, Paulina Ferrada‐Ernst, Nicola Habjan, Annika E Peters, Dirk H Busch, Tobias Feuchtinger
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives Exploiting the forces of human T cells for treatment has led to the current paradigm of emerging immunotherapy strategies. Genetic engineering of the T‐cell receptor (TCR) redirects specificity, ablates alloreactivity and brings
Externí odkaz:
https://doaj.org/article/ab8c3e6d149d403c8001e8a0cca41eae
Autor:
Armin Wolf, Semjon Willier, Johannes Raedler, Franziska Blaeschke, Dana Stenger, Montserrat Pazos Escudero, Florian Jurgeleit, Thomas G P Grünewald, Vera Binder, Irene Schmid, Michael H Albert, Tobias Feuchtinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Relapsed/refractory B-precursor acute lymphoblastic leukemia (BCP-ALL) remains a major therapeutic challenge in pediatric hematology. Chimeric antigen receptor (CAR) T cells targeting CD19 have shown remarkable initial response rates in BC
Externí odkaz:
https://doaj.org/article/27c8b25d5ad94f20ab2fed383e907a26
CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy
Autor:
Christoph Klein, Theresa Kaeuferle, Maximilian Hastreiter, Jonas Wilhelm, Meino Rohlfs, Marion Subklewe, Tobias Feuchtinger, Dana Stenger, Paula Rothämel, Franziska Blaeschke, Michael H. Albert, Vera Binder, Irene Schmid, Semjon Willier
Publikováno v:
Blood. 137:1037-1049
Emerging immunotherapies such as chimeric antigen receptor T cells have advanced the treatment of acute lymphoblastic leukemia. In contrast, long-term control of acute myeloid leukemia (AML) cannot be achieved by single lineage-specific targeting whi
Autor:
Stefan Canzar, Francisca Rojas Ringeling, Martin A. Horstmann, Christoph Klein, Theresa Kaeuferle, Dana Stenger, Mareike Lepenies, Semjon Willier, Franziska Blaeschke, Gabriele Escherich, Vera Binder, Meino Rohlfs, Tobias Feuchtinger, Martin Zimmermann
Publikováno v:
Leukemia. 34:2607-2620
Interaction of malignancies with tissue-specific immune cells has gained interest for prognosis and intervention of emerging immunotherapies. We analyzed bone marrow T cells (bmT) as tumor-infiltrating lymphocytes in pediatric precursor-B cell acute
Autor:
Nicola Habjan, Franziska Blaeschke, Felicitas Rataj, Bruno L Cadilha, Theresa Kaeuferle, Sebastian Kobold, Jasmin Mahdawi, Tobias Feuchtinger, Robbie G. Majzner, Antonia Apfelbeck, Dana Stenger, Eva Ortner, Mohamed-Reda Benmebarek, Mareike Lepenies, Semjon Willier, Dirk Büsch
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-6 (2021)
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-6 (2021)
Autor:
Johannes Raedler, Thomas G. P. Grunewald, Florian Jurgeleit, Semjon Willier, Irene Schmid, Vera Binder, Tobias Feuchtinger, Franziska Blaeschke, Armin Wolf, Dana Stenger, Montserrat Pazos Escudero, Michael H. Albert
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
BackgroundRelapsed/refractory B-precursor acute lymphoblastic leukemia (BCP-ALL) remains a major therapeutic challenge in pediatric hematology. Chimeric antigen receptor (CAR) T cells targeting CD19 have shown remarkable initial response rates in BCP
Autor:
Ramin Lotfi, Theresa Kaeuferle, Mario Assenmacher, Andrew Kaiser, Dana Stenger, Michaela Döring, Semjon Willier, Judith Feucht, Franziska Blaeschke, Tobias Feuchtinger
Publikováno v:
Cancer Immunology, Immunotherapy. 67:1053-1066
Relapsed/refractory B-precursor acute lymphoblastic leukemia (pre-B ALL) remains a major therapeutic challenge. Chimeric antigen receptor (CAR) T cells are promising treatment options. Central memory T cells (Tcm) and stem cell-like memory T cells (T
Autor:
Tobias Feuchtinger, Kilian Schober, Theresa Kaeuferle, Ramin Lotfi, Tanja A. Stief, Sebastian Kobold, Beate Wagner, Dana Stenger, Felicitas Rataj, Irmela Jeremias, Franziska Blaeschke, Binje Vick, Semjon Willier, Thomas G. P. Grunewald, Dirk H. Busch
Publikováno v:
Blood
Blood 136, 1407-1418 (2020)
Blood 136, 1407-1418 (2020)
Anti-CD19 chimeric antigen receptor (CAR) T cells showed significant antileukemic activity in B-precursor acute lymphoblastic leukemia (ALL). Allogeneic, HLA-mismatched off-the-shelf third-party donors may offer ideal fitness of the effector cells, b