Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Dana, Gaddy"'
Autor:
Claire Stenhouse, Katherine M. Halloran, Emily C. Hoskins, Robyn M. Moses, Guoyao Wu, Heewon Seo, Gregory A. Johnson, Larry J. Suva, Dana Gaddy, Fuller W. Bazer
Publikováno v:
Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Tissue non-specific alkaline phosphatase (TNSALP; encoded by the ALPL gene) has a critical role in the postnatal regulation of phosphate homeostasis, yet how TNSALP activity and expression are regulated during pregnancy remain lar
Externí odkaz:
https://doaj.org/article/059d64e8adcc4536afb04484791aec85
Autor:
Connor P. Dolan, Tae-Jung Yang, Katherine Zimmel, Felisha Imholt, Osama Qureshi, Alyssa Falck, Joshua Gregory, Macie Mayes, Kayla Ritchie, Hannah Koester, Benjamin Daniel, Mingquan Yan, Ling Yu, Larry J. Suva, Dana Gaddy, Lindsay A. Dawson, Ken Muneoka, Regina Brunauer
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Structural regeneration of amputated appendages by blastema-mediated, epimorphic regeneration is a process whose mechanisms are beginning to be employed for inducing regeneration. While epimorphic regeneration is classically studi
Externí odkaz:
https://doaj.org/article/70345e430d4741d68396046541651079
Autor:
Michelle A. Hook, Alyssa Falck, Ravali Dundumulla, Mabel Terminel, Rachel Cunningham, Arthur Sefiani, Kayla Callaway, Dana Gaddy, Cédric G. Geoffroy
Publikováno v:
Biology, Vol 11, Iss 2, p 189 (2022)
After spinal cord injury (SCI), 80% of individuals are diagnosed with osteopenia or osteoporosis. The dramatic loss of bone after SCI increases the potential for fractures 100-fold, with post-fracture complications occurring in 54% of cases. With the
Externí odkaz:
https://doaj.org/article/8de778be49974f218b42beea2b8bb319
Autor:
Sarah M. Zimmerman, Roberta Besio, Melissa E. Heard-Lipsmeyer, Milena Dimori, Patrizio Castagnola, Frances L. Swain, Dana Gaddy, Alan B. Diekman, Roy Morello
Publikováno v:
AIMS Genetics, Vol 5, Iss 1, Pp 24-40 (2018)
The Leprecan protein family which includes the prolyl 3-hydroxylase enzymes (P3H1, P3H2, and P3H3), the closely related cartilage-associated protein (CRTAP), and SC65 (Synaptonemal complex 65, aka P3H4, LEPREL4), is involved in the post-translational
Externí odkaz:
https://doaj.org/article/05234aec63d04665a22ea2877fc4d07d
Autor:
Paulina D. Ketcham, Felisha Imholt, Mingquan Yan, Hannah M. Smith, Shabistan Asrar, Ling Yu, Connor P. Dolan, Osama Qureshi, Yu‐Lieh Lin, Ian Xia, Patrick C. Hall, Alyssa R. Falck, Kirby M. Sherman, Dana Gaddy, Larry J. Suva, Ken Muneoka, Regina Brunauer, Lindsay A. Dawson
Publikováno v:
Wound Repair and Regeneration. 31:17-27
Humans and mice have the ability to regenerate the distal digit tip, the terminal phalanx (P3) in response to amputation. What distinguishes P3 regeneration from regenerative failure is formation of the blastema, a proliferative structure that underg
Autor:
Fatma F. Mohamed, Michael B. Chavez, Shannon Huggins, Joshua Bertels, Alyssa Falck, Larry J. Suva, Brian L. Foster, Dana Gaddy
Publikováno v:
Journal of Bone and Mineral Research. 37:2005-2017
Hypophosphatasia (HPP) is the inherited error-of-metabolism caused by mutations in ALPL, reducing the function of tissue-nonspecific alkaline phosphatase (TNAP/TNALP/TNSALP). HPP is characterized by defective skeletal and dental mineralization and is
Autor:
Brandon M. Wagner, Jerid W. Robinson, Timothy C. R. Prickett, Eric A. Espiner, Sundeep Khosla, Dana Gaddy, Larry J. Suva, Lincoln R. Potter
Publikováno v:
Calcified Tissue International. 111:506-518
Autor:
Connor P. Dolan, Felisha Imholt, Mingquan Yan, Tae-Jung Yang, Joshua Gregory, Osama Qureshi, Katherine Zimmel, Kirby M. Sherman, Hannah M. Smith, Alyssa Falck, Eric Leininger, Ling Yu, Regina Brunauer, Larry J. Suva, Dana Gaddy, Lindsay A. Dawson, Ken Muneoka
Publikováno v:
Dev Biol
It is long-established that innervation-dependent production of neurotrophic factors is required for blastema formation and epimorphic regeneration of appendages in fish and amphibians. The regenerating mouse digit tip and the human fingertip are mam
Autor:
Claire, Stenhouse, Katherine M, Halloran, Emily C, Hoskins, Makenzie G, Newton, Robyn M, Moses, Heewon, Seo, Kathrin A, Dunlap, Michael C, Satterfield, Dana, Gaddy, Gregory A, Johnson, Guoyao, Wu, Larry J, Suva, Fuller W, Bazer
Publikováno v:
Biology of Reproduction. 106:1126-1142
This study aimed to determine whether the acceleration of conceptus development induced by the administration of exogenous progesterone (P4) during the preimplantation period of pregnancy alters calcium, phosphate, and vitamin D signaling at the mate
Autor:
Dana Gaddy, Claire Stenhouse, Katherine M Halloran, Fuller W. Bazer, Larry J. Suva, Makenzie G Newton
Publikováno v:
Biology of Reproduction. 105:232-243
Mineralization of the fetal mammalian skeleton requires a hypercalcemic gradient across the placenta from mother to fetus. However, the mechanisms responsible for maintaining the placental transport of calcium remain poorly understood. This study aim