Protocol for a phase 3, randomised, active-control study of four-factor prothrombin complex concentrate versus frozen plasma in bleeding adult cardiac surgery patients requiring coagulation factor replacement: the LEX-211 (FARES-II) trial

Autor: Éric Dumont, Lusine Abrahamyan, Stuart Mccluskey, Angela Jerath, Humara Poonawala, Andrew Stevens, Jeannie Callum, Alan Tinmouth, Daniel Wong, Gianluigi Bisleri, Tarit Saha, David Mazer, Hilary Grocott, Jane Yang, Jeff Kinney, Yoan Lamarche, Damon Scales, George Tomlinson, Fuad Moussa, Andrew Shih, Michelle Zeller, Melanie Tokessy, Keyvan Karkouti, Vivek Rao, Summer Syed, Lilia Kaustov, Sophia Wong, Lani Lieberman, Kamrouz Ghadimi, Philippe Demers, Penny Johnson, Jerrold H Levy, Justyna Bartoszko, Miki Peer, Michael Law, Michelle Wong, Mackenzie Quantz, Antoine Rochon, Fraser Rubens, Shagun Jain, Yulia Lin, Katerina Pavenski, Deep Grewal, Deborah DuMerton, Darrin Payne, Saba Ansari, Robert Mayer, Rebecca Randall, Aftab Malik, Bethany Smethurst, Laura Molnar, Angela Sirosky-Yanyk, Mark Peterson, Christopher Harle, Etienne Couture, Diem Tran, Cristina Solomon, Sigurd Knaub, Kenichi A Tanaka, Blaine Achen, Sukhpal Brar, Matthew Coley, Dana Devine, Alana Flexman, Camila Machado de Souza, Maria Rosal Martins, Terri Sun, Rob Tanzola, Mathew Yan, Raffael Zamper, Jo Carrol, Nishanthi Liyanage, Simryn Selby, Reezanoor Kabir, Shelley Oliver, Alioska Escorcia, Susana Medic, Michelle Mozel, Ramanjot Kaur, Kelly Bizovie, Sarah Buchko, Raven Arly Gonzales, Korey Sutherland, Jenna Van Roekel, Alveena Babul, Ken Tanaka, Kofi Vandyck, Amir Butt, Hisako Okada, Robert Tanzola, Reegan Tod, Aiden Scholey, Wafaa Haider, Ester Cisneros-Aguilera, Alexandre Bergeron, Genevieve Belanger, Darren Mullane, Bevan Hughes, Sakara Hutspardol, Shirley Lim, Jian Mi, Debbie Kalar, Matthew Eang, Erick Lorenzana-Saldivar, Edward P Chen, Akash Gupta, Philip Lau, Pablo Perez D’Empaire, Chantal Armali, Amie Malkin, Connie Colavecchia, Harley Meirovich, Annie Bergeron, Francois Laforge, Kim Paradis, Nathalie Gagne, Marie Soleil Saillant, Marie-Claude Vézina, Olivier Royer, Marie-Ève Charest, Lee-Anne Fochesato, Yuxin Bai, Iqbal Jaffar, Nour Alhomsi, Janine Guevarra, Erin Jamula, Wan Chien (Betty) Hsu, Abbey Drew, Hakan Buyukdere, Drashtee Patel, Elizabeth Watt, Hadia Arabi Katbi, Kim Luciano, Amy Moorehead, Kamola Kasimova, Farzana Tasmin, Cielo Bingley, Victoria Barkley, Tob Reegan, Marianna Qu, Jessica Xiong, Sophie Robichaud, Christy Peterson, Manu Jairath, Mathew Tang, Jennita Aariaratnam, Leron DuMerton, Lucas Drew, Sahrish Masood, Toni Tidy, Elizabeth Krok

Publikováno v: BMJ Open, Vol 14, Iss 8 (2024)

Introduction Reduced thrombin generation is an important component of post cardiopulmonary bypass (CPB) coagulopathy. To replenish coagulation factors and enhance thrombin generation in bleeding surgical patients, frozen plasma (FP) and four-factor p

Externí odkaz: https://doaj.org/article/f4b23ce7268143bca04256dccb1c3cbf

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Navigating imperfect policies to donate plasma: Survey on plasma donation and a pilot plasma donation program among men who have sex with men in Canada

Autor: Elisabeth Vesnaver, Emily Gibson, Mindy Goldman, Terrie Butler‐Foster, Nolan E. Hill, Don Lapierre, Richard MacDonagh, Kyle A. Rubini, Glenndl Miguel, Andrew Rosser, Paul MacPherson, Amelia Palumbo, Taylor Randall, William Osbourne‐Sorrell, Sheila F. O'Brien, Joanne Otis, Mark Greaves, Taim Bilal Al‐Bakri, Marco Reid, Maximilian Labrecque, Marc Germain, Shane Orvis, Andrew T. Clapperton, Dana Devine, Justin Presseau

Publikováno v: Transfusion.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0492b8998d8e5305434c57087c9d9c3b
https://doi.org/10.1111/trf.17398

Trauma 2021: Trauma Association of Canada Annual Scientific Meeting, Vancouver, British Columbia (virtual), April 12–16, 2021Perceptions of a trauma team regarding in situ simulationEpidemiology of submersion injuries in Canadian children and adolescents: 1990–2018A survey of medical and administrative directors on REBOA use in Canadian trauma centresCut to the chase: comparing cutting tools in the exposure of simulated trauma patientsPediatric major trauma. Anaesthesia education: airway, breathing, coffee and cases 2020–2021Geriatric trauma care at a level 1 trauma centre: Are we following best practice?Was the introduction of a provincially standardized consensus statement for postintubation analgesia and sedation associated with increased use of associated pharmacological therapies in New Brunswick?Are there important variations in the care of adult trauma patients with isolated, nonoperative subdural hematomas between those admitted to a neurosurgical centre and those admitted to a non-neurosurgical centre for their entire inpatient stay?Flattening the curve on the negative psychosocial impact of trauma on the family of acute care trauma survivors: a quantitative studyDoes ACLS belong in ATLS? Seeking evidence during resuscitative thoracotomyAutologous omental harvest for microvascular free flap reconstruction of a severe traumatic scalp degloving injury: a case reportDerivation and validation of actionable quality indicators targeting reductions in complications for injury admissionsASA dosing practices in the management of blunt cerebrovascular injury: a retrospective reviewA retrospective analysis of bicycle lane collisions in Vancouver, British Columbia, from 2012 to 2017Evaluating the Screening, Brief Intervention and Referral to Treatment (SBIRT) process at Vancouver General HospitalAlcohol use and trauma in Alberta after COVID-19 lockdown: overrepresentation and undertreatment are opportunities for improvementMental health and addiction diagnoses are linked to increased violent injuries and gaps in provision of resources during the COVID-19 pandemicPain management strategies after orthopedic trauma in a level 1 trauma centre: a descriptive study with a view of optimizing practicesStudy to Actively Warm Trauma Patients (STAY WARM): a feasibility pilot evaluationPrehospital trauma care in civilian and military settings including cold environments: a systematic review and knowledge gap analysisAntibiotic administration in open fractures: adherence to guidelines at a Canadian trauma centreAre we meeting massive transfusion protocol activation and blood product delivery times in trauma patients? A retrospective review from 2014 to 2018Unplanned returns to the operating room: a quality improvement initiative at a level 1 trauma centreStopping the bleed: the history and rebirth of Canadian freeze-dried plasmaThe state of the evidence for emergency medical services (EMS) care of prehospital severe traumatic brain injury: an analysis of appraised research from the Prehospital Evidence-based Practice programA mixed methods study of a paramedic falls referral program in Nova ScotiaFirst presentations of psychiatric illness at a level 1 trauma centreAlcohol and substance abuse screening in pediatric trauma patients: examining rates of screening and implementing a screen for the pediatric populationMeasuring behavioural quality and quantity of team leaders during simulated interprofessional trauma careImproving rural trauma outcomes: a structured trauma-training program for rural family physicians with enhanced surgical skills — a pilot projectTrauma treatment: evidence-based response to psychological needs after a natural disasterHow prepared are Canadian trauma centres for mass casualty incidents?The catalytic effect of multisource feedback for trauma teams: a pilot studyRetrievable inferior vena cava filter for primary prophylaxis of pulmonary embolism in at-risk trauma patients: a feasibility trialValue of data collected by the medical examiner service on the quality of alcohol and toxicology testing in fatal motor vehicle collisionsPrehospital narrow pulse pressure predicts need for resuscitative thoracotomy and emergent surgical intervention after traumaImpact of a geriatric consultation service on outcomes in older trauma patients: a retrospective pre–post studyExploring physical literacy as a condition of fall mechanism in older adultsIs the use of business intelligence software helpful in planning injury prevention campaigns?Exposure to endotracheal intubation among trauma patients in level 5 trauma centres in New Brunswick — a retrospective reviewAre early specialist consultations helpful predictors of those who require care in level 1 or 2 designated trauma centres?Neurologic outcomes after traumatic cardiac arrest: a systematic reviewClosed-loop communication in the trauma bay: identifying opportunities for team performance improvement through a video review analysisEmbolization in nonsplenic trauma: outcomes at a Canadian trauma hospitalThe matrix: grouping ICD-10-CA injury codes by body region and nature of injury for reporting purposesEvaluation of low-value clinical practices in acute trauma care: a multicentre retrospective studyTrauma 101: a virtual case-based trauma conference as an adjunct to medical educationPhysiologic considerations, indications and techniques for ECLS in trauma: experience of a level 1 trauma centreEngaging patients in the selection of trauma quality indicatorsStrategies aimed at preventing chronic opioid use in trauma and acute care surgery: a scoping reviewAugmented reality surgical telementoring for leg fasciotomyIdentification of high-risk trauma patients requiring major interventions for traumatic hemorrhage: a prospective study of clinical gestaltEvaluating best practices in trauma care of older adultsBetween paradigms: comparing patient and parent experiences of injured adolescents treated at pediatric or adult trauma centresEarly outcomes after implementation of chest trauma management protocol in Vancouver General HospitalUtility of diagnostic peritoneal lavage versus focused abdominal sonography for trauma in penetrating abdominal injuryTime to definitive surgery and survival in pediatric patients younger than 18 years with gunshot woundsThe effect of chronic obstructive lung disease on post-traumatic acute respiratory distress syndrome: predictors of morbidity and mortalityThe association between injury type and clinical outcomes in patients with traumatic renal injury after nephrectomyWhen low complication rates are a bad sign: the negative impact of introducing an electronic medical record on TQIP data completenessClinical handover from paramedic services to the trauma team: a video review analysis of the IMIST-AMBO protocol implementationGeriatric Recovery and Enhancement Alliance in Trauma (GREAT) multidisciplinary quality improvement initiative: improving process and outcome measures for geriatric trauma patientsIncreasing the safety of inadvertent iliac artery device deployment with the COBRA-OS, a novel low-profile REBOA deviceIs it better to watch before or listen while doing? A randomized trial of video-modelling versus telementoring for out-of-scope tube thoracostomy insertion performed by search and rescue medicsIndications for prehospital civilian tourniquet application by first responders: an expert consensus opinion of military physicians by the Delphi method

Autor: Alex Merkle, Andrew Kirkpatrick, Adam Power, Nori Bradley, Cara Elliott, Keren Guiab, Teresa Evans, Mahwash Siddiqi, Renée-Anne Poirier, Matthew Yeung, Matthew Guttman, Alexandre Tran, John McPherson, Caroline Côté, Agathe Lorthios-Guilledroit, Sadiq Al Khaboori, Simon Farquharson, Lynne Moore, Deanna Fong, Brad Moffat, Avneesh Bhangu, Daniel Shi, Ian Watson, Julie Ringuette, Allison Chisholm, Brandy Tanenbaum, Jacinthe Lampron, Morgan Schellenberg, Karen Ssebazza, R. Mason Curtis, Leah Allen, Arshia P. Javidan, Judi Malone, Philip Dawe, Abdulrahman Saleh Alballa, Ioana Bratu, Erika Schmitz, Judah Goldstein, Jennifer Greene, Marcus Moore, Joseph Tropiano, Vivian Leung, Yashita Upadhyaya, Rachel Strauss, Sonia Grzelak, Hayley Forbes, Samantha Albacete, Joanne Sadler, Amy Makish, Alyssa MacLean, William Brigode, Asha Pereira, Susan Benjamin, Stacey McEachern, Sidney Frattini, Ruth Bird, Caleb Cummings, Sean Hurley, Mike O’Leary, Olga Bednarek, Sam Jessula, Samuel Minor, Jason Emsley, Colleen Sameoto, Eleanor Fitzpatrick, Mete Erdogan, Robert Green, Aaron Sibley, Trevor Jain, Brent Nicholson, Henrik Stryhn, Cengiz Karsli, Rivanna Stuhler, Elaine Ng, Angela Coates, Paul Engels, Akke Neel Talsma, Michelle Lobchuk, Vipavee Thongpriwan, Shawn Cahill, Justin Mis, Fredric Starr, Faran Bokhari, Adil Ladak, Ryan Snelgrove, Haili Wang, Hollie Power, Laura Allen, Rob Leeper, Neil Parry, Ian Ball, Kelly Vogt, Danielle Rawls, Geoff Ramler, Ellie Andres, Nasira Lakha, Angie Brisson, Jennah Merchant, Sandy Widder, Melanie Berube, Marc-Aurèle Gagnon, Stéphane Pelet, Étienne Belzile, Amie Kron, Jeannie Callum, Chantal Armali, Dimpy Modi, Lowyl Notario, Pablo Perez, Bourke Tillmann, Dylan Pannell, Andrew Beckett, Homer Tien, Avery Nathens, Luis Da Luz, Laure Perrier, Isabella Menchetti, Erik Blondal, Henry Peng, Wendy Sullivan-Kwantes, Neal Irfan, Tarek Razek, Ann Wilson, Derek Goltz, Sonshire Figueira, Heather Knight, Dana Devine, Craig Jenkins, Judah Goldstien, Yves Leroux, Jen McVey, Ryan Brown, Janel Swain, Alix Carter, Dana Fidgen, Suzanne Baker, Francine Butts, Scott McCulloch, Izabella Opra, Jan Jensen, Andrew Travers, Pantelis Andreou, Marie Earl, Grace Warner, Mojgan Rezaaifar, Doug Wilkins, Krista Lai, Aleena Amjad Hafeez, Scott Goldberg, Egide Abahuje, Charles Pozner, Steven Yule, Sarah Parker, Roger Dias, Richard Simons, Emilie Joos, Victoria Vogt Haines, Jacqueline Linder, Andrew Cameron, Graham Cleghorn, Tim Chaplin, Fran Priestap, Amol Mujoomdar, Stewart Kribs, Crystal Kearley, Joshua LeBlanc, Natthida Owattanapanich, Joelle Getrajdman, Kazuhide Matsushima, Lydia Lam, Kenji Inaba, Debra Eagles, Lara Khoury, Marie-Joe Nemnom, Joy Moors, Dean Kriellaars, Drew Mitchell, Lisa Totton, Leisa Ouelett, Janet Vautour, Tushar Pishe, Christie McLaren, Chris Evans, Will Thomas-Boaz, Corey Freedman, Christine Li, Cathy Yoshy, Daniele Wiseman, Randi Mao, Eva Yiguan Liu, Lucy Lan, Takhliq Amir, Jimmy Yan, Kevin Singh, Alexandra Allard-Coutu, Morad Hameed, Naisan Garraway, George Isac, Hussein Kanji, Gordon Finlayson, Gavin Tansley, Alex Lee, Catherine Gonthier, Amina Belcaïd, Marie-France Duranceau, Catherine Truchon, François Lauzier, Gregory Berry, Lorraine Tremblay, Marc Martel, Gabrielle Pagé, Anne-Marie Pinard, David Evans, Kadija Perreault, Caroline Sirois, Alexis Turgeon, Max Talbot, Christopher Kennedy, Rich Hilsden, Gerard Slobogean, Tyler Lamb, Maher Matar, Shannon Fernando, Jeffrey Perry, Christian Vaillancourt, Justin Nathens, Andrea Phillips, Barbara Haas, Brent Hage, Natalie Yanchar, James McKay, Francesca Bryan, Asma Qureshi, Ghulam Saadat, Andrew Khalifa, Matthew Kaminsky, Aly Aly, Andrew Roberts, Matt Kaminsky, Jasmine Zahid, Thomas Messer, Robyn Keen, Kyla Hoogers, Arshia Javidan, Martin Johnston, Kristen Morch, Lauren Scott, Ni Lam, Asha Parekh, Corey Tomlinson, Nigel Donley, Jessica Mckee, Juan Wachs, Mike Kay, Seth Holland

Publikováno v: Canadian Journal of Surgery. 64:S37-S64

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::612bac55381590bc35813832700fda2e
https://doi.org/10.1503/cjs.014121

Staff perspectives on barriers and enablers to implementing alternative source plasma eligibility criteria for gay, bisexual, and other men who have sex with men

Autor: Gisell Castillo, Elisabeth Vesnaver, Emily Gibson, Terrie Butler‐Foster, Mindy Goldman, Nolan E. Hill, Andrew Rosser, Don Lapierre, Kyle A. Rubini, Richard MacDonagh, Glenndl Miguel, Amelia Palumbo, Paul MacPherson, Taylor Randall, William Osbourne‐Sorrell, Sheila F. O'Brien, William Bridel, Joanne Otis, Mark Greaves, Taim Bilal Al‐Bakri, Marco Reid, Maximilian Labrecque, Marc Germain, Shane Orvis, Andrew T. Clapperton, Dana Devine, Justin Presseau

Publikováno v: Transfusion. 62(8)

Canadian Blood Services introduced new eligibility criteria that allows some sexually active gay, bisexual, and other men who have sex with men (gbMSM) to donate source plasma, marking a significant change from time-based deferral criteria. We aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645303346a4b66012fdfdf08daad3df8
https://pubmed.ncbi.nlm.nih.gov/35834537