Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Dana, Cavill"'
1
Passive transfer of Sjögren's syndrome IgG produces the pathophysiology of overactive bladder
Autor: Tom P. Gordon, Fang Wang, Sally A. Waterman, Vicki Maughan, Anthony J.F. Smith, Michael W. Jackson, Dana Cavill
Publikováno v: Arthritis & Rheumatism. 50:3637-3645
Objective The presence, in patients with primary and secondary Sjogren's syndrome (SS), of autoantibodies that acutely inhibit M3 muscarinic receptor (M3R)–mediated bladder contractions is difficult to reconcile with the fact that symptoms of detru
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e30d9eab62868e23adba2b3663c3b8d9
https://doi.org/10.1002/art.20625
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2
Tolerance through Indifference: Autoreactive B Cells to the Nuclear Antigen La Show No Evidence of Tolerance in a Transgenic Model
Autor: Catherine L. Keech, Brett D. Aplin, Andrea de Kauwe, Tom P. Gordon, Dana Cavill, James McCluskey
Publikováno v: Flinders University PURE
Scopus-Elsevier
Systemic autoimmune diseases are characterized by the production of high titer autoantibodies specific for ubiquitous nuclear self-Ags such as DNA, Sm, and La (SS-B), so the normal mechanisms of B cell tolerance to disease-associated nuclear Ags have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf67f4627ce0a79010983c5cb14fcd3c
https://doi.org/10.4049/jimmunol.171.11.5890
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3
Vasoactive intestinal peptide binding autoantibodies in autoimmune humans and mice
Autor: Tom P. Gordon, Stephanie Planque, Yogesh Bangale, Hiroaki Taguchi, Gita Bhatia, Sudhir Paul, Dana Cavill, Yasuhiro Nishiyama, Frank C. Arnett
Publikováno v: Peptides. 23:2251-2257
Autoantibodies capable of binding the immunoregulatory neuropeptide vasoactive intestinal peptide (VIP) were detected in the sera of a mouse strain prone to autoimmune disease due to the lpr mutation (MRL/ lpr ). The autoantibodies were not present i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a2d17e828ef64df34404c514ce5597
https://doi.org/10.1016/s0196-9781(02)00265-6
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4
Anti-La/SSB antibodies transported across the placenta bind apoptotic cells in fetal organs targeted in neonatal lupus
Autor: Tom P. Gordon, Jenny Hiscock, Jill P. Buyon, Dana Cavill, J Bradley, Hai B. Tran, Peter J. Macardle
Publikováno v: Arthritis & Rheumatism. 46:1572-1579
Objective To determine whether La and/or Ro epitopes on apoptotic cells in fetal organs that are targeted in neonatal lupus syndrome (NLS) are accessible for binding by autoantibodies in vivo, we traced the fate of transplacental autoantibodies in a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18d63c4f7e1a237ae83dba95212c941
https://doi.org/10.1002/art.10316
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7
Passive transfer of Sjogren's syndrome IgG produces the pathophysiology of overactive bladder
Autor: Fang, Wang, Michael W, Jackson, Vicki, Maughan, Dana, Cavill, Anthony J, Smith, Sally A, Waterman, Tom P, Gordon
Publikováno v: Arthritis and rheumatism. 50(11)
The presence, in patients with primary and secondary Sjogren's syndrome (SS), of autoantibodies that acutely inhibit M(3) muscarinic receptor (M3R)-mediated bladder contractions is difficult to reconcile with the fact that symptoms of detrusor overac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2b61c88a452714a58a4c192f4d0e533
https://pubmed.ncbi.nlm.nih.gov/15529387
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8
Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome
Autor: Dana Cavill, Sally A. Waterman, Tom P. Gordon
Publikováno v: Flinders University PURE
Functional antimuscarinic M3 receptor (M3R) autoantibodies have been shown to inhibit cholinergic neurotransmission at the postsynaptic level and appear to mediate parasympathetic dysfunction, including sicca symptoms in Sjogren's syndrome (SS). The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20169bb1a430a7a87dcfcfdcd6e30e9
https://pubmed.ncbi.nlm.nih.gov/15030576
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9
Antiidiotypic antibodies neutralize autoantibodies that inhibit cholinergic neurotransmission
Autor: Tom P. Gordon, Dana Cavill, Sally A. Waterman
Publikováno v: Flinders University PURE
Objective Functional autoantibodies that inhibit M3 muscarinic receptor (M3R)–mediated neurotransmission have been reported in patients with Sjogren's syndrome (SS) and in patients with scleroderma. Because of limited reports that intravenous immun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c6cb3e90b7ac90944e150087e3816e4
https://pubmed.ncbi.nlm.nih.gov/14674012
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