Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Dan-ni Ren"'
1
Akademický článek
Babao Dan Alleviates Cancer Cachexia in Mice Via Inhibiting IL-6/STAT3 Signaling Pathway
Autor: Zhengliang Qiu BS, Da Wo PhD, Xiaomei Zhong BS, Jinxiao Chen PhD, En Ma MS, Jia He PhD, Jun Peng MD, PhD, Weidong Zhu MD, PhD, Dan-ni Ren MD, PhD
Publikováno v: Integrative Cancer Therapies, Vol 22 (2023)
Background: Cancer cachexia is a common but severe condition that causes muscle wasting, body weight loss, and progressive functional impairment, affecting over 50% of cancer patients. Currently, there are no effective treatments that can alleviate c
Externí odkaz: https://doaj.org/article/e54348becebb4cf2889c116c5a6f63fa
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2
Akademický článek
Qingda granule prevents obesity-induced hypertension and cardiac dysfunction by inhibiting adverse Akt signaling activation
Autor: Qian Gao, En Ma, Jinxiao Chen, Qiqin Zhao, Jia He, Jun Peng, Weidong Zhu, Dan-ni Ren, Da Wo
Publikováno v: Heliyon, Vol 8, Iss 12, Pp e12099- (2022)
Obesity rates have rapidly increased worldwide and obesity-related diseases such as hypertension and cardiovascular diseases have become leading factors for global morbidity and mortality. Currently, there are no effective treatments that can prevent
Externí odkaz: https://doaj.org/article/acce930fa2c941fcb8cd971a36d50360
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3
Akademický článek
Network pharmacology-based analysis in determining the mechanisms of Huoxin pill in protecting against myocardial infarction
Autor: Jia He, Da Wo, En Ma, Qing Wang, Jinxiao Chen, Jun Peng, Weidong Zhu, Dan-ni Ren
Publikováno v: Pharmaceutical Biology, Vol 59, Iss 1, Pp 1191-1202 (2021)
Context Huoxin pill (HXP) is a commonly used TCM prescription for treatment of cardiovascular diseases. However, its mechanism in protecting against myocardial infarction (MI) remains unknown. Objective We performed a network pharmacology analysis to
Externí odkaz: https://doaj.org/article/eb446c7defbb4f92936b394ffbd5831d
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4
Akademický článek
Deletion of low-density lipoprotein-related receptor 5 inhibits liver Cancer cell proliferation via destabilizing Nucleoporin 37
Autor: Jinxiao Chen, Da Wo, En Ma, Hongwei Yan, Jun Peng, Weidong Zhu, Yong Fang, Dan-ni Ren
Publikováno v: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-8 (2019)
Abstract Background LRP5/6 are co-receptors in Wnt/β-catenin pathway. Recently, we discovered multiple β-catenin independent functions of LRP5/6 in tumor cells and in the diseased heart. Nucleoporin 37 (NUP37) is an important component of the nucle
Externí odkaz: https://doaj.org/article/7a7e2c9ed4a6493eb39ddc26ee426e9e
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5
Data from LRP6 Ectodomain Prevents SDF-1/CXCR4-Induced Breast Cancer Metastasis to Lung
Autor: Weidong Zhu, Dan-ni Ren, Jun Peng, Chunli Liang, Zuoren Yu, Daxin Chen, Liang Zheng, Limei Li, En Ma, Peng Liu, Hongwei Yan, Da Wo, Jinxiao Chen, Jiankang Zhang
Purpose:Lung metastasis is an important cause of breast cancer–related deaths, in which SDF-1/CXCR4 signaling pathway plays a critical role. Single transmembrane protein LRP6 is viewed as an oncogene via activating the Wnt/β-catenin signaling path
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c12e62907e767ac9b2400725a716d9b
https://doi.org/10.1158/1078-0432.c.6528032.v1
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7
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β‑catenin signaling
Autor: Da Wo, Dan-ni Ren, Weidong Zhu, Qing Wang, Jinxiao Chen, En Ma, Jia He, Jun Peng
Publikováno v: Journal of Cellular and Molecular Medicine
Myocardial infarction (MI) is one of the leading causes of death worldwide, and due to the widespread and irreversible damage caused, new therapeutic treatments are urgently needed in order to limit the degree of ischaemic damage following MI. Aberra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5125d00aff29fea0bc790615aa9248c8
https://doi.org/10.1111/jcmm.17028
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9
Network pharmacology-based analysis in determining the mechanisms of Huoxin pill in protecting against myocardial infarction
Autor: Qing Wang, Da Wo, Dan-ni Ren, En Ma, Weidong Zhu, Jinxiao Chen, Jun Peng, Jia He
Publikováno v: Pharmaceutical Biology, Vol 59, Iss 1, Pp 1191-1202 (2021)
Pharmaceutical Biology
article-version (VoR) Version of Record
Context Huoxin pill (HXP) is a commonly used TCM prescription for treatment of cardiovascular diseases. However, its mechanism in protecting against myocardial infarction (MI) remains unknown. Objective We performed a network pharmacology analysis to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913b6dad2465d412d22b8fc4458b6679
https://doaj.org/article/eb446c7defbb4f92936b394ffbd5831d
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10
IGFBP‐4 enhances VEGF‐induced angiogenesis in a mouse model of myocardial infarction
Autor: Dan-ni Ren, En Ma, Jun Peng, Yong Fang, Hongwei Yan, Qiongyu Li, Weidong Zhu, Jinxiao Chen, Da Wo
Publikováno v: Journal of Cellular and Molecular Medicine
Vascular endothelial growth factor (VEGF) is a well‐known angiogenic factor, however its ability in promoting therapeutic angiogenesis following myocardial infarction (MI) is limited. Here, we aimed to investigate whether dual treatment with insuli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98eeb105683d8e5f494d618366e01a5b
http://europepmc.org/articles/PMC7417680
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