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On the catalytic mechanism of bacteriophage HK97 capsid crosslinking

Autor: Dan-ju Tso, Craig L. Peebles, Robert L. Duda, Roger W. Hendrix, Joshua B. Maurer

Publikováno v: Virology. 506:84-91

During maturation of the phage HK97 capsid, each of the 415 capsid subunits forms covalent bonds to neighboring subunits, stabilizing the capsid. Crosslinking is catalyzed not by a separate enzyme but by subunits of the assembled capsid in response t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83b3036f0231cae3a830daf2359be1f
https://doi.org/10.1016/j.virol.2017.03.011

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Detection of DNA mutations associated with mitochondrial diseases by Agilent 2100 bioanalyzer

Autor: Yau-Huei Wei, Tom Yang, Ching-You Lu, Yuh-Jyh Jong, Dan-Ju Tso

Publikováno v: Clinica Chimica Acta. 318:97-105

Background: Molecular analysis of mitochondrial DNA (mtDNA) has provided a final diagnosis for many of the mitochondrial diseases. We evaluated the Agilent 2100 bioanalyzer (Agilent Technologies, Palo Alto, CA) to determine whether the system could r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7595e1621a2be392332bbc5a00d7a5
https://doi.org/10.1016/s0009-8981(01)00809-9

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Transient contacts on the exterior of the HK97 procapsid that are essential for capsid assembly

Autor: Robert L. Duda, Dan-ju Tso, Roger W. Hendrix

The G-loop is a 10-residue glycine-rich loop that protrudes from the surface of the mature bacteriophage HK97 capsid at the C-terminal end of the long backbone helix of major capsid protein subunits. The G-loop is essential for assembly, is conserved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee79025a697b9dff83d40f3f2a1dfe4
https://europepmc.org/articles/PMC4020191/

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The thymidylate synthase gene of Hz-1 virus: A gene captured from its lepidopteran host

Autor: Hong-Hwa Chen, Hsien Jen Cheng, Wen Bin Yeh, Dan Ju Tso, Ting-Feng Wu

Publikováno v: Insect Molecular Biology. 10:495-503

The sequence analysis of a thymidylate synthase gene was identified in the Hz-1 virus HindIII-D fragment. The viral thymidylate synthase gene encodes a protein of 295 amino acids, and is closely related to that of insect, mammals and herpesvirus. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57ae39b9855dcfc4e5613fe711b9c7b7
https://doi.org/10.1046/j.0962-1075.2001.00289.x

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Clinical phenotype and the G11778A mutation of mitochondrial DNA in patients with Leber’s hereditary optic neuropathy in Taiwan

Autor: Ling Yuh Kao, Dan Ju Tso, Hung Chou Kuo, Hsin Chen Lee, Chin Chang Huang, Chun Che Chu, Yau-Huei Wei, Tzu Ning Yu

Publikováno v: Neuro-Ophthalmology. 26:207-216

We report the clinical manifestations and mitochondrial DNA (mtDNA) mutations of nine Chinese patients with Leber’s hereditary optic neuropathy from seven families in Taiwan. The nine probands were all males, aged 19 to 43 years at the time of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f5dbb826ad58466f2fbb984b18f5de0
https://doi.org/10.1076/noph.26.4.207.15871

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Prenatal diagnosis of a fetus harboring an intermediate load of the A3243G mtDNA mutation in a maternal carrier diagnosed with MELAS syndrome

Autor: Chia-Yu Ou, Dan-Ju Tso, Cheng-Feng Lee, Chia-Wei Liou, Te-Yao Hsu, Yin-Jou Chou, Yau-Huei Wei

Publikováno v: Prenatal diagnosis. 24(5)

We prenatally diagnosed MELAS syndrome in a fetus whose mother and older brother had the MELAS-specific A3243G mutation. The mutant mtDNA level of the amniotic fluid cells was not significantly different from that of the postnatal peripheral blood an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad853abdda942cfe6ddf0ebf7b76a1d
https://pubmed.ncbi.nlm.nih.gov/15164411

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