Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dan-Hua He"'
Autor:
Shi-Bing Zhang, Ming Hong, Xiao-Yang Sun, Da Huang, Dan-Hua He, Yu-Fei Chen, Yong Yuan, Yong-Qiang Liu
Publikováno v:
Acta Materia Medica, Vol 1, Iss 3, Pp 302-313 (2022)
Silybin (SB), a natural flavonoid isolated from Silybum marianum, has been used to treat hepatic fibrosis in clinical settings and as a dietary supplement, because of its hepatoprotective potential. Numerous studies have shown that SB also exerts pro
Externí odkaz:
https://doaj.org/article/4ee6dec25f0948aa940e73a4635ea403
Autor:
Shi-Bing Zhang, Ming Hong, Xiao-Yang Sun, Da Huang, Dan-Hua He, Yu-Fei Chen, Yong Yuan, Yong-Qiang Liu
Publikováno v:
Acta Materia Medica, Vol 2, Iss 2, Pp 191-191 (2023)
Externí odkaz:
https://doaj.org/article/fb76e7792e864143af5324c92c61f68b
Autor:
Ye Lei, Hong-Fen Shen, Qi-Wen Li, Sheng Yang, Hong-Ting Xie, Xu-Feng Li, Mei-Ling Chen, Jia-Wei Xia, Sheng-Chun Wang, Guan-Qi Dai, Ying Zhou, Ying-Chun Li, Shi-Hao Huang, Dan-Hua He, Zhi-Hao Zhou, Jin-Ge Cong, Xiao-Lin Lin, Tao-Yan Lin, Ai-Bing Wu, Dong Xiao, Sheng-Jun Xiao, Xin-Ke Zhang, Jun-Shuang Jia
Publikováno v:
Aging.
Autor:
Yi-Le Zhou, Yongzhi Lu, Xiang-Zhen Fan, Shi-Bing Zhang, Qi Wang, Su-Fen Wei, Yu-Fei Chen, Li Siyi, Xianjun Yu, Ming Hong, Yongqiang Liu, Dan-Hua He
Publikováno v:
Cancer Science
Skp2 is overexpressed in multiple cancers and plays a critical role in tumor development through ubiquitin/proteasome‐dependent degradation of its substrate proteins. Drugs targeting Skp2 have exhibited promising anticancer activity. Here, we ident
Autor:
Ling Hu, Wei Liu, Li Siyi, Huafeng Pan, Sha Xiong, Yong-Xian Cheng, Yongqiang Liu, Yong-Ming Yan, Dan-Hua He, Su-Fen Wei, Qi Wang, Yi-Le Zhou
Publikováno v:
Acta Pharmacologica Sinica
Neuroinflammation is one of the critical events in neurodegenerative diseases, whereas microglia play an important role in the pathogenesis of neuroinflammation. In this study, we investigated the effects of a natural sesquiterpene lactone, 6-O-angel
Autor:
Xiaowei Ye, Dan-Hua He, Su-Fen Wei, Yongzhi Lu, Shi-Bing Zhang, Qi Wang, Yongqiang Liu, Hong Wang, Xiang-Zhen Fan
Publikováno v:
Biochemical pharmacology. 190
Aberrant activation of the Hedgehog (Hh) pathway is implicated in the pathogenesis and development of multiple cancers, especially Hh-driven medulloblastoma (MB). Smoothened (SMO) is a promising therapeutic target of the Hh pathway in clinical cancer
Autor:
Dan-Hua He, Huafeng Pan, Yongqiang Liu, Su-Fen Wei, Yu-Fei Chen, Shi-Bing Zhang, Qi Wang, Xiang-Zhen Fan
Publikováno v:
Phytomedicine. 91:153689
Background Intrinsic and acquired chemoresistance remains a critical challenge in lung cancer chemotherapy. Fanconi anemia (FA) pathway plays an important role in antagonizing the cytotoxic effects of chemotherapeutics by repairing DNA damage. We rec
Publikováno v:
Phytomedicine. 80:153402
Background Although great achievements have been made in the field of cancer therapy, chemotherapy and radiotherapy remain the mainstay cancer therapeutic modalities. However, they are associated with various side effects, including cardiocytotoxicit
Publikováno v:
Biomedical Reports. 4:583-588
The present study aimed to investigate the effects of the Fructus Ligustri Lucidi (FLL) extract and its monomers quercetin and oleanolic acid on the adhesion and migration of human epidermal melanocytes (MCs) and intracellular actin. The human epider