Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Dan-Arin Silasi"'
Autor:
Emanuele Perrone, Paola Manara, Salvatore Lopez, Stefania Bellone, Elena Bonazzoli, Aranzazu Manzano, Luca Zammataro, Anna Bianchi, Burak Zeybek, Natalia Buza, Joan Tymon‐Rosario, Gary Altwerger, Chanhee Han, Gulden Menderes, Gloria S. Huang, Elena Ratner, Dan‐Arin Silasi, Masoud Azodi, Pei Hui, Peter E. Schwartz, Giovanni Scambia, Alessandro D. Santin
Publikováno v:
Molecular Oncology, Vol 14, Iss 3, Pp 645-656 (2020)
Endometrial cancer is the most common gynecologic malignancy in developed countries. The antibody–drug conjugate (ADC) sacituzumab govitecan (SG) targets trophoblast cell‐surface antigen‐2 (Trop‐2) – a cell‐surface glycoprotein highly exp
Externí odkaz:
https://doaj.org/article/4855a08bc9b94673965f1e87191a9728
Autor:
Emily M. Webster, Ghanshyam S. Yadav, Stefan Gysler, Blair McNamara, Jonathan Black, Joan Tymon-Rosario, Burak Zeybek, Chanhee Han, Christopher K. Arkfeld, Vaagn Andikyan, Gulden Menderes, Gloria Huang, Masoud Azodi, Dan-Arin Silasi, Alessandro D. Santin, Peter E. Schwartz, Elena S. Ratner, Gary Altwerger
Publikováno v:
Gynecologic Oncology Reports, Vol 34, Iss , Pp 100667- (2020)
Research within a gynecologic oncology population has lagged behind the uptake in use of medical cannabis for symptom control. This study seeks to evaluate patient experience with prescribed medical cannabis obtained through licensed dispensaries in
Externí odkaz:
https://doaj.org/article/efa0abb420a54db1b2dd8238713b1aa0
Autor:
Emanuele Perrone, Salvatore Lopez, Burak Zeybek, Stefania Bellone, Elena Bonazzoli, Silvia Pelligra, Luca Zammataro, Aranzazu Manzano, Paola Manara, Anna Bianchi, Natalia Buza, Joan Tymon-Rosario, Gary Altwerger, Chanhee Han, Gulden Menderes, Elena Ratner, Dan-Arin Silasi, Masoud Azodi, Pei Hui, Peter E. Schwartz, Giovanni Scambia, Alessandro D. Santin
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. Sacituzumab govitecan (SG) is a novel antibody-drug-conjugate (ADC) targeting trophoblast-antigen-2 (Trop-2), a cell surface glycoprotein highly expressed in many
Externí odkaz:
https://doaj.org/article/2f3ecf6859594b69a06c011b962dbb6a
Autor:
Benjamin B. Albright, Jonathan D. Black, Rachel Passarelli, Stefan Gysler, Margaret Whicker, Gary Altwerger, Gulden Menderes, Natalia Buza, Pei Hui, Alessandro D. Santin, Masoud Azodi, Dan-Arin Silasi, Elena S. Ratner, Babak Litkouhi, Peter E. Schwartz
Publikováno v:
Gynecologic Oncology Reports, Vol 23, Iss C, Pp 28-33 (2018)
Objective: This study sought to evaluate characteristics of cases of free-floating tumor fragments within the lumen of fallopian tubes (‘floaters’) on final pathology for Type I and Type II endometrial adenocarcinoma, including relationships with
Externí odkaz:
https://doaj.org/article/e302ba2713a344eab5ae5966c15b15a2
Autor:
Chaarushi Ahuja, Joan Tymon-Rosario, Douglas Rottmann, Rita Abi Raad, Dan-Arin Silasi, Alla Vash-Margita
Publikováno v:
Journal of Pediatric and Adolescent Gynecology. 35:505-508
Autor:
Alessandro D. Santin, W. Mark Saltzman, Babak Litkouhi, Peter E. Schwartz, Dan-Arin Silasi, Masoud Azodi, Elena Ratner, Julio Alvarenga, Mitchell Clark, Christopher de Haydu, Gary Altwerger, Luca Zammataro, Federica Predolini, Fan Yang, Elena Bonazzoli, Carlton L. Schwab, Jonathan D. Black, Gulden Menderes, Jiajia Cui, Stefania Bellone, Ken Lin, Salvatore Lopez, Ileana Bortolomai, Erik M. Shapiro, Yang Deng, Emiliano Cocco
Supporting information include 3 tables and 3 figures. Table 1 describes the Patients characteristics from which primary cell lines were established. Table 2 the characteristics of ovarian tumor samples from which RNA was extracted. Table 3 the chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cc6f12ded653f5d436b438a15835e6
https://doi.org/10.1158/1535-7163.22504240.v1
https://doi.org/10.1158/1535-7163.22504240.v1
Autor:
Alessandro D. Santin, Wim H.A. Dokter, C. Marco Timmers, Miranda M.C. van der Lee, Patrick H. Beusker, Peter Goedings, Peter E. Schwartz, Babak Litkouhi, Masoud Azodi, Dan-Arin Silasi, Elena Ratner, Salvatore Lopez, Serena Wong, Pei Hui, Natalia Buza, Emiliano Cocco, Christopher De Haydu, Federica Predolini, Francesca Ferrari, Elena Bonazzoli, Carlton L. Schwab, Stefania Bellone, Gulden Menderes, Jonathan Black
Exposure of all nine cell lines to scalar concentrations of ADC for a total of 6 days. IC50 dose response curves of SYD985, T-DM1 and ADC isotype control in all 9 primary USC cell lines with differential HER2 expression tested in vitro (i.e., three w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab78a65c7648dc7729220df637ca7280
https://doi.org/10.1158/1535-7163.22507497.v1
https://doi.org/10.1158/1535-7163.22507497.v1
Autor:
Alessandro D. Santin, Wim H.A. Dokter, C. Marco Timmers, Miranda M.C. van der Lee, Patrick H. Beusker, Peter Goedings, Peter E. Schwartz, Babak Litkouhi, Masoud Azodi, Dan-Arin Silasi, Elena Ratner, Salvatore Lopez, Serena Wong, Pei Hui, Natalia Buza, Emiliano Cocco, Christopher De Haydu, Federica Predolini, Francesca Ferrari, Elena Bonazzoli, Carlton L. Schwab, Stefania Bellone, Gulden Menderes, Jonathan Black
Uterine serous carcinoma (USC) is an aggressive form of endometrial cancer. Up to 35% of USC may overexpress the HER2/neu oncogene at strong (i.e., 3+) levels by IHC while an additional 40% to 50% express HER2/neu at moderate (2+) or low (1+) levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96803aeb0319979ba122bff602aec038
https://doi.org/10.1158/1535-7163.c.6538710.v1
https://doi.org/10.1158/1535-7163.c.6538710.v1
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Grade 3 endometrioid and uterine serous carcinomas (USC) account for the vast majority of endometrial cancer deaths. The purpose of this study was to determine folic acid receptor alpha (FRα) expression in these biologically aggressive (type II) end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81646ed0c38f7c706dc160a71539783
https://doi.org/10.1158/1535-7163.c.6537780.v1
https://doi.org/10.1158/1535-7163.c.6537780.v1
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Determination by ICso of IMGN853 cytotoxicity compared to controls, ADC isotype and M9346A, in primary USC cell lines (ie, END(K) 149 and ARK19) with 2+ FRα expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53be3b3c29dfd1353c8c582dd60bb588
https://doi.org/10.1158/1535-7163.22504572
https://doi.org/10.1158/1535-7163.22504572