Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Dan Yang Huang"'
Autor:
Leticia Quintanilla-Martinez, Paola Capuano, Martin S. Judenhofer, Bernd J. Pichler, Mentor Sopjani, Dan Yang Huang, Carsten A. Wagner, Gerti Stange, Michael Föller, Madhuri Bhandaru, Balasaheb Siraskar, Jürg Biber, Ioana Alesutan, Anand Rotte, Leonid Tyan, David A. Pearce, Florian Lang, Ganesh Pathare, Daniela S. Kempe
Publikováno v:
Kidney international
Insulin and growth factors activate the phosphatidylinositide-3-kinase pathway, leading to stimulation of several kinases including serum- and glucocorticoid-inducible kinase isoform SGK3, a transport regulating kinase. Here, we explored the contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6897d1714c074825e252bac0733dae47
Autor:
Krishna M. Boini, Kan Wang, Ferruh Artunc, Dietmar Kuhl, Kerstin Amann, Jan J. Brosens, Rexhep Rexhepaj, Florian Lang, Dan Yang Huang
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 294:R2008-R2013
Maternal stress and malnutrition modify intrauterine fetal development with impact on postnatal blood pressure, nutrient, water, and electrolyte metabolism. The present study explored the possible involvement of maternal serum- and glucocorticoid-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72086a8df054808b62414209b6d2e602
https://doi.org/10.1152/ajpregu.00737.2007
https://doi.org/10.1152/ajpregu.00737.2007
Autor:
Christoph Köhle, Dan Yang Huang, Hartmut Osswald, Almut Grenz, Hua Zhang, Klaus Unertl, Holger K. Eltzschig, Tobias Eckle, Manfred Wehrmann
Publikováno v:
American Journal of Physiology-Renal Physiology. 292:F475-F485
Renal failure from ischemia contributes to morbidity and mortality. Ischemic preconditioning (IP) represents a powerful strategy for kidney protection, and recent advances in transgenic mice may help elucidate its molecular mechanisms. However, murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850b3d8dcef886a51ec12cbdbf2cde2d
https://doi.org/10.1152/ajprenal.00275.2006
https://doi.org/10.1152/ajprenal.00275.2006
Autor:
Susanne Ullrich, Ferruh Artunc, Björn Friedrich, Krishna M. Boini, Peer Wulff, Dan Yang Huang, Monica Palmada, Jeyaganesh Rajamanickam, Volker Vallon, Dietmar Kuhl, Florian Lang, Hartmut Osswald
Publikováno v:
American Journal of Physiology-Renal Physiology. 291:F1264-F1273
Mineralocorticoids enhance expression and insulin stimulates activity of the serum- and glucocorticoid-inducible kinase SGK1, which activates the renal epithelial Na+ channel (ENaC). Under a salt-deficient diet, SGK1 knockout mice ( sgk1−/−) excr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d78e11d5c5b9a66cff1a32fc84012f9
https://doi.org/10.1152/ajprenal.00299.2005
https://doi.org/10.1152/ajprenal.00299.2005
Autor:
Florian Lang, Björn Friedrich, Hans-Ulrich Häring, Monica Palmada, Dietmar Kuhl, Florian Grahammer, Ferruh Artunc, Dan Yang Huang, Hartmut Osswald, Anita M. Hennige, Volker Vallon, Diana Avram, Krishna M. Boini, Susanne Ullrich, Christoph Boehmer, Peer Wulff
Publikováno v:
Diabetes. 55:2059-2066
Excess salt intake decreases peripheral glucose uptake, thus impairing glucose tolerance. Stimulation of cellular glucose uptake involves phosphatidylinositide-3-kinase (PI-3K)-dependent activation of protein kinase B/Akt. A further kinase downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edc2c7fe85762dee010841f0d3fc13cb
https://doi.org/10.2337/db05-1038
https://doi.org/10.2337/db05-1038
Autor:
Peer Wulff, Ulrich Flögel, Karin Klingel, Dan Yang Huang, Florian Lang, Susanne Berchtold, Jürgen Schrader, Agnes Görlach, Nancy D. Dalton, Amanda W. Wyatt, Hartmut Osswald, Jürgen Daut, Florian Grahammer, John Ross, Björn Friedrich, Rachida S. BelAiba, Azeemudeen Hussain, Volker Vallon, Dietmar Kuhl, Reinhard Kandolf
Publikováno v:
Journal of Molecular Medicine. 84:396-404
The mineralocorticoids aldosterone and deoxycorticosterone acetate (DOCA) stimulate renal tubular salt reabsorption, increase salt appetite, induce extracellular volume expansion, and elevate blood pressure. Cardiac effects of mineralocorticoids incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5b8903f06ec2699251e3328529f449
https://doi.org/10.1007/s00109-005-0027-z
https://doi.org/10.1007/s00109-005-0027-z
Autor:
Marco Metzger, Hartmut Osswald, Volker Vallon, Dan Yang Huang, Dietmar Kuhl, Peer Wulff, Lothar Just, Björn Friedrich, Florian Lang, Krishna M. Boini
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 290:R935-R944
Serum- and glucocorticoid-inducible kinase (SGK1) is transcriptionally upregulated by mineralocorticoids and activated by insulin. The kinase stimulates the renal epithelial Na+channel and may thus participate in blood pressure regulation. Hyperinsul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5c6fa1131bff0e13206d92b9ee4742
https://doi.org/10.1152/ajpregu.00382.2005
https://doi.org/10.1152/ajpregu.00382.2005
Autor:
Karin Klingel, Azeemudeen Hussain, Dan Yang Huang, Ferruh Artunc, Florian Lang, Florian Grahammer, Amanda W. Wyatt, Dietmar Kuhl, Reinhard Kandolf, Kerstin Amann, Volker Vallon
Publikováno v:
Cellular Physiology and Biochemistry. 17:137-144
Mineralocorticoid excess leads to cardiac fibrosis, a leading cause of morbidity and mortality. Cardiac hypertrophy and fibrosis are inhibited by the glycogen synthase kinase GSK3 which itself is a target of protein kinase B (PKB) and the serum and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e04ebb0b56e263d04067766e5dc68a0
https://doi.org/10.1159/000092075
https://doi.org/10.1159/000092075
Autor:
Amanda W. Wyatt, Florian Grahammer, Dan Yang Huang, Volker Vallon, Peer Wulff, Dietmar Kuhl, Hartmut Osswald, Florian Lang
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 289:R395-R401
Mineralocorticoids modify salt balance by both stimulating salt intake and inhibiting salt loss. Renal salt retention is accomplished by upregulation of reabsorption, an effect partially mediated by serum- and glucocorticoid-inducible kinase 1 (SGK1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c2a71d5ffab15a95ef9a74919642d7
https://doi.org/10.1152/ajpregu.00731.2004
https://doi.org/10.1152/ajpregu.00731.2004
Autor:
Dan Yang Huang, Peer Wulff, Dietmar Kuhl, Florian Lang, Volker Vallon, Harald Völkl, Johannes Loffing
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 288:R4-R10
Aldosterone plays a pivotal role in NaCl and K+homeostasis by stimulation of Na+reabsorption and K+secretion in the aldosterone-sensitive distal nephron (ASDN). Recent studies demonstrated that the serum- and glucocorticoid-regulated kinase 1 (Sgk1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc75d245aeeaf9fdb056584e4fe43d3
https://doi.org/10.1152/ajpregu.00369.2004
https://doi.org/10.1152/ajpregu.00369.2004