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pro vyhledávání: '"Dan Yahalom"'
Autor:
Rani Zananiri, Sivasubramanyan Mangapuram Venkata, Vera Gaydar, Dan Yahalom, Omri Malik, Sergei Rudnizky, Oded Kleifeld, Ariel Kaplan, Arnon Henn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
RecBCD is a remarkably fast DNA helicase. Using a battery of biophysical methods, Zananiri et. al reveal additional, non-catalytic ATP binding sites that increase the ATP flux to the catalytic sites that allows fast unwinding when ATP is scarce.
Externí odkaz:
https://doaj.org/article/3abd36f307634b5ab5baa58a5b34d1af
Autor:
Rani Zananiri, Sivasubramanyan Mangapuram Venkata, Vera Gaydar, Dan Yahalom, Omri Malik, Sergei Rudnizky, Oded Kleifeld, Ariel Kaplan, Arnon Henn
Publikováno v:
Nature communications. 13(1)
The RecBCD helicase initiates double-stranded break repair in bacteria by processively unwinding DNA with a rate approaching ∼1,600 bp·s−1, but the mechanism enabling such a fast rate is unknown. Employing a wide range of methodologies — inclu