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pro vyhledávání: '"Dan Spatt"'
Publikováno v:
Genetics. 222
Spn1/Iws1 is an essential eukaryotic transcription elongation factor that is conserved from yeast to humans as an integral member of the RNA polymerase II elongation complex. Several studies have shown that Spn1 functions as a histone chaperone to co
Autor:
James Chuang, Magdalena Murawska, Dan Spatt, Dhawal Jain, Olga V. Viktorovskaya, Fred Winston, L. Stirling Churchman, Francheska Lopez-Rivera, Peter J. Park, Natalia I. Reim
Publikováno v:
Genes Dev
Histone chaperones are critical for controlling chromatin integrity during transcription, DNA replication, and DNA repair. Three conserved and essential chaperones, Spt6, Spn1/Iws1, and FACT, associate with elongating RNA polymerase II and interact w
Autor:
Dan Spatt, Magdalena Murawska, James Chuang, Peter J. Park, Natalia I. Reim, Fred Winston, Dhawal Jain, L. Stirling Churchman, Francheska Lopez-Rivera, Olga V. Viktorovskaya
SUMMARYHistone chaperones are critical for controlling chromatin integrity during transcription, DNA replication, and DNA repair. We have discovered that the physical interaction between two essential histone chaperones, Spt6 and Spn1/Iws1, is requir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92bcbfb6d03df35cc647a3dc6164a989
https://doi.org/10.1101/2020.11.04.368589
https://doi.org/10.1101/2020.11.04.368589
Autor:
Magdalena Murawska, James Chuang, Fred Winston, Dan Spatt, L. Stirling Churchman, Olga V. Viktorovskaya, Stephen M. Doris
SUMMARYSpt6 is a conserved factor that controls transcription and chromatin structure across the genome. Although Spt6 is viewed as an elongation factor,spt6mutations inSaccharomyces cerevisiaeallow elevated levels of transcripts from within coding r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6420330ca08e2ae96c8e378d4fae4c3c
Autor:
Scott P. Kallgren, Dan Spatt, Patrick Cramer, Burak H. Alver, Kerstin C. Maier, Ameet Shetty, Carina Demel, Fred Winston, Peter J. Park
Publikováno v:
Molecular Cell
Spt5 is an essential and conserved factor that functions in transcription and co-transcriptional processes. However, many aspects of the requirement for Spt5 in transcription are poorly understood. We have analyzed the consequences of Spt5 depletion
Publikováno v:
Eukaryotic Cell. 11:1067-1074
The Schizosaccharomyces pombe inv1 + gene encodes invertase, the enzyme required for hydrolysis of sucrose and raffinose. Transcription of inv1 + is regulated by glucose levels, with transcription tightly repressed in high glucose and strongly induce
Autor:
Dan Spatt, Fred Winston, James Chuang, Olga V. Viktorovskaya, L. Stirling Churchman, Stephen M. Doris, Magdalena Murawska
Publikováno v:
Molecular Cell. 72:687-699.e6
Summary Spt6 is a conserved factor that controls transcription and chromatin structure across the genome. Although Spt6 is viewed as an elongation factor, spt6 mutations in Saccharomyces cerevisiae allow elevated levels of transcripts from within cod
Publikováno v:
Genetics. 188(2)
We have studied hypoxic induction of transcription by studying the seripauperin (PAU) genes of Saccharomyces cerevisiae. Previous studies showed that PAU induction requires the depletion of heme and is dependent upon the transcription factor Upc2. We