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Autor:
Elliott M. Antman, Christian T. Ruff, Robert P. Giugliano, Dan Salazar, James J. Hanyok, Tomas S. Bocanegra, Michele Mercuri, Eugene Braunwald, Indravadan Patel, Minggao Shi, Sharon Crugnale, Carolyn H. McCabe
Publikováno v:
American Heart Journal. 160:635-641.e2
Background Vitamin K antagonists have been the standard oral antithrombotic used for more than a half century for prevention and treatment of thromboembolism. Their limitations include multiple food and drug interactions and need for frequent monitor