Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Dan SIMIONESCU"'
Publikováno v:
Romanian Journal of Cardiology, Vol 31, Iss 3, Pp 501-510 (2021)
Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement. Regenerative Medicine and T
Externí odkaz:
https://doaj.org/article/a8d3a907ad8a4d649cddf5ad2e5e703a
Autor:
Ionela MOVILEANU, Dan Octavian NISTOR, Leslie SIERAD, Klara BRINZANIUC, Codrut OPRITA, Marius Mihai HARPA, Terezia PREDA, Ovidiu COTOI, Hussam AL HUSSEIN, Hamida AL HUSSEIN, Alexandru CHERTES, Horatiu SUCIU, Agneta SIMIONESCU, Dan SIMIONESCU
Publikováno v:
Romanian Journal of Cardiology, Vol 31, Iss 3, Pp 555-563 (2021)
The inherent limitations of current heart valve substitutes create the premise for the Tissue Engineered Heart Valve (TEHV), considered the perfect substitute. We aimed to compare in vitro hemodynamic performances of our TEHV, the conventional prosth
Externí odkaz:
https://doaj.org/article/b11565e6e826474586df3d3bd2a29cf2
Autor:
Dan Simionescu, Nishanth Tharayil, Elizabeth Leonard, Wenda Carlyle, Alex Schwarz, Kelvin Ning, Christopher Carsten, Juan Carlos Carrillo Garcia, Alexander Carter, Collin Owens, Agneta Simionescu
Publikováno v:
Bioengineering, Vol 10, Iss 8, p 936 (2023)
Pentagalloyl glucose (PGG) is currently being investigated as a non-surgical treatment for abdominal aortic aneurysms (AAAs); however, the molecular mechanisms of action of PGG on the AAA matrix components and the intra-luminal thrombus (ILT) still n
Externí odkaz:
https://doaj.org/article/749b85ecce224ee3a316826c704b39d8
Autor:
Dan Simionescu, PhD, Megan Casco, PhD, Jake Turner, BS, Nicholas Rierson, BS, Jianing Yue, MD, PhD, Kelvin Ning, MS
Publikováno v:
JVS - Vascular Science, Vol 1, Iss , Pp 69-80 (2020)
Objective: The goal of the present study was to test the safety and efficacy of chemical stabilization of the arterial extracellular matrix as a novel nonoperative treatment of abdominal aortic aneurysms (AAAs) in a clinically relevant large animal m
Externí odkaz:
https://doaj.org/article/be8d7f6993bc4c3580a0dd130a80cd4f
Autor:
Ionela Movileanu, Marius Harpa, Hussam Al Hussein, Lucian Harceaga, Alexandru Chertes, Hamida Al Hussein, Georg Lutter, Thomas Puehler, Terezia Preda, Carmen Sircuta, Ovidiu Cotoi, Dan Nistor, Adrian Man, Bogdan Cordos, Radu Deac, Horatiu Suciu, Klara Brinzaniuc, Megan Casco, Leslie Sierad, Margarita Bruce, Dan Simionescu, Agneta Simionescu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Introduction: Pediatric patients with cardiac congenital diseases require heart valve implants that can grow with their natural somatic increase in size. Current artificial valves perform poorly in children and cannot grow; thus, living-tissue-engine
Externí odkaz:
https://doaj.org/article/3941edf86721482fabef76e1788269e0
Autor:
Alexandru Filippi, Alina Constantin, Nicoleta Alexandru, Geanina Voicu, Cristina Ana Constantinescu, Daniela Rebleanu, Madalina Fenyo, Dan Simionescu, Agneta Simionescu, Ileana Manduteanu, Adriana Georgescu
Publikováno v:
Cell Transplantation, Vol 29 (2020)
Diabetes reduces the number and induces dysfunction in circulating endothelial progenitor cells (EPCs) by mechanisms that are still uncovered. This study aims to evaluate the number, viability, phenotype, and function of EPCs in dyslipidemic mice wit
Externí odkaz:
https://doaj.org/article/5dd1edf56e3e479bb6edb3c032e323b6
Autor:
Megan Casco, Timothy Olsen, Austin Herbst, Grace Evans, Taylor Rothermel, Lauren Pruett, Dan Simionescu, Richard Visconti, Frank Alexis
Publikováno v:
Bioengineering, Vol 4, Iss 1, p 4 (2017)
Nanotechnologies have been integrated into drug delivery, and non-invasive imaging applications, into nanostructured scaffolds for the manipulation of cells. The objective of this work was to determine how the physico-chemical properties of magnetic
Externí odkaz:
https://doaj.org/article/316a9182302c45a0af8f05f00f613b44
Publikováno v:
Romanian Journal of Cardiology, Vol 31, Iss 3, Pp 501-510 (2021)
Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement. Regenerative Medicine and T
Autor:
Hussam Al Hussein, Marius Harpa, Ionela Movileanu, Hamida Al Hussein, Horatiu Suciu, Klara Branzaniuc, Dan Simionescu
Publikováno v:
Revista de Chimie. 70:1826-1828
Many methods of stem cells collection and isolation from various tissue types harvested either from small or large experimental animals or from human tissues have been published so far, all evaluating them as a potential source of adult mesenchymal s
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Tissue engineered blood vessels based on biological scaffolds seeded with autologous cells are currently being developed, but very little information exists regarding their fate in the complex diabetic environment. Diabetes is a major risk factor for