Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dan Kozome"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Loops are small secondary structural elements that play a crucial role in the emergence of new enzyme functions. However, the evolutionary molecular mechanisms how proteins acquire these loop elements and obtain new function is poorly unders
Externí odkaz:
https://doaj.org/article/7d902c4067374e09a5b74da8be1ce099
Publikováno v:
Biochemistry. 62:210-220
The rapid growth of sequence databases over the past two decades means that protein engineers faced with optimizing a protein for any given task will often have immediate access to a vast number of related protein sequences. These sequences encode in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccaecf3996502bb5eda3e899dc7360e
https://doi.org/10.1021/acs.biochem.1c00757
https://doi.org/10.1021/acs.biochem.1c00757
Loops are small secondary structural elements that play a crucial role in the emergence of new enzyme functions. However, our understanding of loop functions is mainly limited to the catalytic loops. To understand the function of remote loops in enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28d17cbb727cceaf17796c48bc923bc
https://doi.org/10.1101/2023.02.27.530148
https://doi.org/10.1101/2023.02.27.530148
Publikováno v:
Appl Environ Microbiol
Chitin is a biopolymer of N-acetyl-d-glucosamine with β-1,4-bond and is the main component of arthropod exoskeletons and the cell walls of many fungi. Chitinase (EC 3.2.1.14) is an enzyme that hydrolyzes the β-1,4-bond in chitin and degrades chitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e5ce03a6353c7e1fa7ceab17c27ed6
https://doi.org/10.1128/aem.00652-22
https://doi.org/10.1128/aem.00652-22
Autor:
Masahiro Goto, Yusuke Tanaka, Dan Kozome, Pugoh Santoso, Toki Taira, Kosuke Minamihata, Noriho Kamiya
Publikováno v:
Bioconjugate chemistry. 32(8)
Enzymatic reaction offers site-specific conjugation of protein units to form protein conjugates or protein polymers with intrinsic functions. Herein, we report horseradish peroxidase (HRP)- and microbial transglutaminase (MTG)-catalyzed orthogonal co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddff3b10b4b513c21c6c5ec2fec3d36d
https://pubmed.ncbi.nlm.nih.gov/34251809
https://pubmed.ncbi.nlm.nih.gov/34251809
Publikováno v:
Planta. 253(6)
A chitin-binding domain could contribute to the antifungal ability of chitinase through its affinity to the fungal lateral wall by hydrophobic interactions. Complementary DNA encoding the antifungal chitinase of gazyumaru (Ficus microcarpa), designat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2925f74fb06d53218aa9cc43e409108c
https://pubmed.ncbi.nlm.nih.gov/33987712
https://pubmed.ncbi.nlm.nih.gov/33987712