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Akademický článek

Comorbidity burden in adult atopic dermatitis: A population‐based study

Autor: Jacob P. Thyssen, Dan Henrohn, Maureen P. Neary, Kirk Geale, Alexander R. Dun, Gustaf Ortsäter, Ingrid Lindberg, Anna De Geer, Petra Neregård, Amy Cha, Joseph C. Cappelleri, William Romero, Laura vonKobyletzki

Publikováno v: JEADV Clinical Practice, Vol 3, Iss 1, Pp 128-141 (2024)

Abstract Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that has been shown to be associated with allergic comorbidities. However, studies examining comorbidities in patients with AD are incomplete, which may contribute to s

Externí odkaz: https://doaj.org/article/682733713428468e82be9f706d9b21ba

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Akademický článek

Influenza Adverse Events in Patients with Rheumatoid Arthritis, Ulcerative Colitis, or Psoriatic Arthritis in the Tofacitinib Clinical Development Programs

Autor: Kevin L. Winthrop, Arne Yndestad, Dan Henrohn, Silvio Danese, Sara Marsal, Maria Galindo, John C. Woolcott, Hyejin Jo, Kenneth Kwok, Andrea B. Shapiro, Thomas V. Jones, Annette Diehl, Chinyu Su, Julian Panés, Stanley B. Cohen

Publikováno v: Rheumatology and Therapy, Vol 10, Iss 2, Pp 357-373 (2022)

Abstract Introduction This post hoc analysis evaluated influenza adverse events (AEs) across rheumatoid arthritis (RA), ulcerative colitis (UC), and psoriatic arthritis (PsA) tofacitinib clinical programs. Methods Available data from phase 1, randomi

Externí odkaz: https://doaj.org/article/636def3d7be64a6abbfb716f2f5fce89

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Akademický článek

Societal economic burden and determinants of costs for atopic dermatitis

Autor: Gustaf Ortsäter, Anna De Geer, Alexander Rieem Dun, Kirk Geale, Ingrid Lindberg, Jacob Pontoppidan Thyssen, Laura B. vonKobyletzki, Alexandra Metsini, Dan Henrohn, Petra Neregård, Amy Cha, Joseph C. Cappelleri, William Romero, Maureen P. Neary

Publikováno v: JEADV Clinical Practice, Vol 1, Iss 4, Pp 326-343 (2022)

Abstract Background Atopic dermatitis (AD) is a common inflammatory skin disease while the economic burden of AD by severity is not adequately understood. Objective To estimate the societal economic burden and to identify cost determinants of AD. Met

Externí odkaz: https://doaj.org/article/885f76a34f1541309327f1bf780ec2de

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Akademický článek

Mycophenolate mofetil for systemic sclerosis: drug exposure exhibits considerable inter-individual variation—a prospective, observational study

Autor: Kristofer Andréasson, Karl Neringer, Dirk M. Wuttge, Dan Henrohn, Jan Marsal, Roger Hesselstrand

Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)

Abstract Objective Mycophenolate mofetil (MMF) is an established therapy for systemic sclerosis (SSc), but its pharmacokinetics in this disease remains unexplored. We have investigated drug exposure in MMF-treated patients with SSc in relation to cli

Externí odkaz: https://doaj.org/article/a5d1abdd5cb04aa587acdf2b37e798e5

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Akademický článek

Effects of pharmacists' interventions on appropriateness of prescribing and evaluation of the instruments' (MAI, STOPP and STARTs') ability to predict hospitalization--analyses from a randomized controlled trial.

Autor: Ulrika Gillespie, Anna Alassaad, Margareta Hammarlund-Udenaes, Claes Mörlin, Dan Henrohn, Maria Bertilsson, Håkan Melhus

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e62401 (2013)

Appropriateness of prescribing can be assessed by various measures and screening instruments. The aims of this study were to investigate the effects of pharmacists' interventions on appropriateness of prescribing in elderly patients, and to explore t

Externí odkaz: https://doaj.org/article/05cc306ee73545ab95e378aa508f6ede

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Influenza Adverse Events in Patients with Rheumatoid Arthritis, Ulcerative Colitis, or Psoriatic Arthritis in the Tofacitinib Clinical Development Programs

Publikováno v: Scientia

This post hoc analysis evaluated influenza adverse events (AEs) across rheumatoid arthritis (RA), ulcerative colitis (UC), and psoriatic arthritis (PsA) tofacitinib clinical programs.Available data from phase 1, randomized phase 2/3/3b/4 clinical tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bdb9b44ccbbf9afb8ee0ad5bd81dda
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502143

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Peripheral Vascular Ageing in Pulmonary Arterial Hypertension as Assessed by Common Carotid Artery Intima Thickness and Intima/Media Thickness Ratio : An Investigation Using Non-Invasive High-Resolution Ultrasound

Autor: Tord Naessen, Gunnar Einarsson, Dan Henrohn, Gerhard Wikström

Background Pulmonary arterial hypertension (PAH; World Heath Organization [WHO] Group 1) is associated with increased pulmonary arterial pressure and resistance, with pulmonary vascular remodelling. The vascular anatomy of the systemic arteries has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f5c27bd9cea14fbbb54231caf815c2
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-504953

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Validation of Patient Identification Algorithms for Atopic Dermatitis Using Healthcare Databases

Autor: Gustaf Ortsäter, Anna De Geer, Kirk Geale, Alexander Rieem Dun, Ingrid Lindberg, Jacob P. Thyssen, Laura von Kobyletzki, Natalia Ballardini, Dan Henrohn, Petra Neregård, Amy Cha, Joseph C. Cappelleri, Maureen P. Neary

Publikováno v: Ortsäter, G, De Geer, A, Geale, K, Rieem Dun, A, Lindberg, I, Thyssen, J P, von Kobyletzki, L, Ballardini, N, Henrohn, D, Neregård, P, Cha, A, Cappelleri, J C & Neary, M P 2022, ' Validation of Patient Identification Algorithms for Atopic Dermatitis Using Healthcare Databases ', Dermatology and Therapy, vol. 12, no. 2, pp. 545-559 . https://doi.org/10.1007/s13555-021-00670-1

Introduction: The use of real-world data offers a possibility to perform large-scale epidemiological studies in actual clinical settings. Despite their many advantages, administrative databases were not designed to be used in research, and the valida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05279ee0ec777835d936659a677b733
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-485444

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Effects of inorganic nitrate in a rat model of monocrotaline‐induced pulmonary arterial hypertension

Autor: Margareta Marusakova, Bianka Zsigmondova, Peter Krenek, Mattias Carlström, Dan Henrohn, Zuzana Kmecova, Jan Klimas, E. Malikova

Publikováno v: Basic & Clinical Pharmacology & Toxicology. 126:99-109

The nitrate-nitrite-nitric oxide (NO) pathway represents an alternative source of NO generation, which is independent of NO synthase and potentiated by hypoxia. Augmentation of this pathway by dietary nitrate has proven favourable effects in several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b9d9cd7de6594e3c6f7f775cd1b706
https://doi.org/10.1111/bcpt.13309

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Mycophenolate mofetil for systemic sclerosis : drug exposure exhibits considerable inter-individual variation-a prospective, observational study

Autor: Dan Henrohn, Dirk M. Wuttge, Karl Neringer, Jan Marsal, Kristofer Andréasson, Roger Hesselstrand

Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Arthritis Research & Therapy

Objective Mycophenolate mofetil (MMF) is an established therapy for systemic sclerosis (SSc), but its pharmacokinetics in this disease remains unexplored. We have investigated drug exposure in MMF-treated patients with SSc in relation to clinical fea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27269b866de4a80960becd2f33a365a1
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-424038

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