Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dan Gincel"'
Autor:
Kevin N. Ramdas, Mark Brody, Brad Herskowitz, Marc Agronin, Jorge G Ruiz, Ana Fuquay, Savannah Rodriguez, Danial Mehranfard, Lisa McClain‐Moss, Dan Gincel, Joshua M. Hare, Anthony A. Oliva
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Kevin Ramdas, Danial Mehranfard, Eric Naioti, Geoff Green, Lisa McClain-Moss, Dan Gincel, Joshua Hare, Anthony Oliva
Publikováno v:
Innovation in Aging. 6:562-562
Aging frailty (AF) is a multidimensional geriatric syndrome that is characterized by physical and cognitive symptoms, increasing the vulnerability of affected older adults to adverse health outcomes. Mechanistically, a low-grade chronic inflammatory
Autor:
Kyle D. Weaver, Betty Tyler, Dan Gincel, Kaleb Yohay, Jaishri O. Blakeley, Andrea C. Pardo, Jeffrey D. Rothstein, Henry Brem
Publikováno v:
Journal of Neurosurgery. 120:854-863
Object The poor outcome of malignant gliomas is largely due to local invasiveness. Previous studies suggest that gliomas secrete excess glutamate and destroy surrounding normal peritumoral brain by means of excitotoxic mechanisms. In this study the a
Autor:
Nazli Boke Sarikahya, Alaa Amash, Essam Abdel-Sattar, Michael Silbermann, Hilal Zaid, Dan Gincel
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017)
Evidence-Based Complementary and Alternative Medicine, Vol 2017 (2017)
Autor:
Andrew M. Watkins, Dwight E. Bergles, Lin Jin, Melissa R. Regan, Jeffrey D. Rothstein, Dan Gincel
Publikováno v:
Experimental Neurology. 203:205-212
The EAAT4 glutamate transporter helps regulate excitatory neurotransmission and prevents glutamate-mediated excitotoxicity in the cerebellum. Immunohistochemistry and in situ hybridization have previously defined a cerebellar cell population expressi
Autor:
H. Brent Clark, Alexis Brice, Marcy R Weatherspoon, Katrin Bürk, Dan Gincel, John W. Day, Katherine A. Dick, Karen R Armbrust, Giovanni Stevanin, Lawrence J. Schut, Joline C. Dalton, Laura P.W. Ranum, Alexandra Durr, Christine Zühlke, Yoshio Ikeda, Jeffrey D. Rothstein
Publikováno v:
Nature Genetics. 38:184-190
We have discovered that beta-III spectrin (SPTBN2) mutations cause spinocerebellar ataxia type 5 (SCA5) in an 11-generation American kindred descended from President Lincoln's grandparents and two additional families. Two families have separate in-fr
Autor:
Carlos A. Pardo, Diana L. Vargas, Coryse St. Hillaire, Katherine Conant, Justin C. McArthur, Jacquelyn Mann, Dan Gincel, Jeffrey D. Rothstein
Publikováno v:
Journal of Neurovirology. 11:535-543
Changes in astrocyte shape and function are known to occur in association with human immunodeficiency virus (HIV) dementia (HIVD). However, the causes and consequences of such changes are not completely understood. In vitro data suggest that changes
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1657(2-3):105-114
The voltage-dependent anion channel (VDAC) provides passage for adenine nucleotides, Ca2+ and other metabolites into and from mitochondria. Here, the intracellular localization and oligomeric organization of VDAC in brain mitochondria and ER are demo
Autor:
Dan Gincel, Varda Shoshan-Barmatz
Publikováno v:
Biophysical Journal. 83(6):3223-3229
The synaptic vesicle protein synaptophysin was solubilized from rat brain synaptosomes with a relatively low concentration of Triton X-100 (0.2%) and was highly purified (above 95%) using a rapid single chromatography step on hydroxyapatite/celite re
Publikováno v:
Journal of Bioenergetics and Biomembranes. 32:571-583
The voltage-dependent anion channel (VDAC), also known as mitochondrial porin, is a large channel permeable to anions, cations, ATP, and other metabolites. VDAC was purified from sheep brain synaptosomes or rat liver mitochondria using a reactive red