Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Dan E. Wells"'
Publikováno v:
Bioinformatics and Biology Insights, Vol 2008, Iss 2, Pp 157-169 (2008)
Externí odkaz:
https://doaj.org/article/9a76733e75224e98aba4e7744364df1a
Publikováno v:
Bioinformatics and Biology Insights, Vol 2, Pp 157-169 (2008)
The results of our bioinformatics analysis have found over 91,000 di-, tri-, and tetranucleotide microsatellites in our survey of 25% of the X. tropicalis genome, suggesting there may be over 360,000 within the entire genome. Within the X. tropicalis
Externí odkaz:
https://doaj.org/article/269e25711b9e4683a643ad395f6cb85f
Publikováno v:
The International Journal of Developmental Biology. 58:27-34
Exostosin 1 (EXT1) is a glycosyltransferase that contributes to the biosynthesis of heparan sulfate proteoglycans (HSPG). Loss of ext1 function leads to the human genetic disorder hereditary multiple exostoses (HME) and inhibits development in mouse,
Autor:
Eiki Koyama, Christina Mundy, Dan E. Wells, Beverly M. Zak, Manuela Schuksz, Yu Yamaguchi, Maurizio Pacifici, Jeffrey D. Esko
Publikováno v:
Bone. 48:979-987
Multiple Hereditary Exostoses (MHE) syndrome is caused by haploinsufficiency in Golgi-associated heparan sulfate polymerases EXT1 or EXT2 and is characterized by formation of exostoses next to growing long bones and other skeletal elements. Recent mo
Publikováno v:
Journal of Neurogenetics. 22:149-166
As part of an ongoing program to identify genes involved in maintaining circadian rhythms of zebrafish, 6,500 mutagenized genomes were screened for dominant mutants affecting circadian locomotor activity. Molecular analysis of one of these mutant lin
Autor:
Ying Tan, Dan E. Wells, Jason P. DeBruyne, Maki Kaneko, Laura Gutierrez, Mark W. Hurd, Gregory M. Cahill
Publikováno v:
Journal of Neurogenetics. 18:403-428
Widespread use of zebrafish (Danio rerio) in genetic analysis of embryonic development has led to rapid advances in the technology required to generate, map and clone mutated genes. To identify genes involved in the generation and regulation of verte
Publikováno v:
Journal of Human Genetics. 47:103-106
The tricho-rhino-phalangeal syndromes (TRPS type I, II, and III) are autosomal dominant disorders sharing the following characteristics: slowly growing and sparse scalp hair, medially thick and laterally thin eyebrows, bulbous tip of the nose, long f
Publikováno v:
DNA Sequence. 13:85-92
The EXT family of genes is involved in the developmentally important biosynthesis of heparan sulfate molecules. Members of the EXT family have a demonstrated role in gastrulation, wing formation in flies, and proper bone development in vertebrates. E
Autor:
L. Zhang, Matthew J. Hilton, Ying Tan, April Hill, Dan E. Wells, Nicholas Brown, P.A. Moreno, M. Reddy, Laura Gutierrez
Publikováno v:
Genomics. 71:192-199
We have developed an integrated map for a 35-cM area of human chromosome 8 surrounding the Langer-Giedion syndrome deletion region. This map spans from approximately 8q22 to 8q24 and includes 10 hybrid cell intervals, 89 polymorphic STSs, 118 ESTs, a