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Akademický článek

Zafirlukast ameliorates lipopolysaccharide and bleomycin-induced lung inflammation in mice

Autor: Tongtong Xue, Qianyi Zhang, Tiantian Zhang, Lingxin Meng, Jing Liu, Dan Chai, Yuming Liu, Zhongyi Yang, Ran Jiao, Yunyao Cui, Jingjing Gao, Xiaohe Li, Aiguo Xu, Honggang Zhou

Publikováno v: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-15 (2024)

Abstract Acute lung injury (ALI) is the result of damage to the capillary endothelia and the alveolar epithelial cell caused by various direct and indirect factors, leading to significant pulmonary interstitial and alveolar edema and acute hypoxic re

Externí odkaz: https://doaj.org/article/9086ce84774b4ff080b8ab6f44bcddc4

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Akademický článek

Remdesivir alleviates skin fibrosis by suppressing TGF-β1 signaling pathway.

Autor: Jianwei Zhang, Xiujun Zhang, Xiaowei Guo, Wenqi Li, Tiantian Zhang, Dan Chai, Yuming Liu, Li Chen, Xiaoyu Ai, Tianyuan Zhou, Wenguo Wei, Xiaoting Gu, Xiaohe Li, Honggang Zhou

Publikováno v: PLoS ONE, Vol 19, Iss 7, p e0305927 (2024)

Fibrotic skin diseases, such as keloids, are pathological results of aberrant tissue healing and are characterized by overgrowth of dermal fibroblasts. Remdesivir (RD), an antiviral drug, has been reported to have pharmacological activities in a wide

Externí odkaz: https://doaj.org/article/f1032cc7bfaf4c61b7a6dd2be178980a

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Akademický článek

Zanubrutinib Ameliorates Cardiac Fibrosis and Inflammation Induced by Chronic Sympathetic Activation

Autor: Wenqi Li, Shuwen Zhu, Jing Liu, Zhigang Liu, Honggang Zhou, Qianyi Zhang, Yue Yang, Li Chen, Xiaowei Guo, Tiantian Zhang, Lingxin Meng, Dan Chai, Guodong Tang, Xiaohe Li, Cheng Yang

Publikováno v: Molecules, Vol 28, Iss 16, p 6035 (2023)

(1) Background: Heart failure (HF) is the final stage of multiple cardiac diseases, which have now become a severe public health problem worldwide. β-Adrenergic receptor (β-AR) overactivation is a major pathological factor associated with multiple

Externí odkaz: https://doaj.org/article/c16ba209530e475da135caca17d8e9e4

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Akademický článek

The Cropping Obstacle of Garlic Was Associated With Changes in Soil Physicochemical Properties, Enzymatic Activities and Bacterial and Fungal Communities

Autor: Jinyang Yu, Yihao Liu, Zuyu Wang, Xiaohui Huang, Dan Chai, Yunfu Gu, Ke Zhao, Xiumei Yu, Zhengbin Shuai, Hanjun Liu, Xiaoping Zhang, Petri Penttinen, Qiang Chen

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

AimsIn garlic cultivation, long-time monoculture has resulted in continuous-cropping obstacles. However, the cause has not been studied to date.MethodsWe analyzed soils from garlic fields in Pengzhou, China, to determine continuous-cropping obstacle

Externí odkaz: https://doaj.org/article/b4eda5ccb4e34b37b7e8fd4e4fbfc392

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