Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Dan Cacsire-Castillo Tong"'
Autor:
Stephanie Koller, Jonatan Kendler, Jasmine Karacs, Andrea Wolf, Caroline Kreuzinger, Isabel Von Der Decken, Felicitas Mungenast, Diana Mechtcheriakova, Wolfgang Schreiner, Andreas Gleiss, Walter Jäger, Dan Cacsire Castillo-Tong, Theresia Thalhammer
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Patients with high-grade serous ovarian cancer (HGSOC) have a very poor overall survival. Current therapeutic approaches do not bring benefit to all patients. Although genetic alterations and molecular mechanisms are well characterized, the molecular
Externí odkaz:
https://doaj.org/article/74479bcb378a49b28f55a675b15f4623
Autor:
Michael Kenn, Dan Cacsire Castillo-Tong, Christian F. Singer, Rudolf Karch, Michael Cibena, Heinz Koelbl, Wolfgang Schreiner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Correctly estimating the hormone receptor status for estrogen (ER) and progesterone (PGR) is crucial for precision therapy of breast cancer. It is known that conventional diagnostics (immunohistochemistry, IHC) yields a significant rate of w
Externí odkaz:
https://doaj.org/article/db1c4ef44c7b4a4b8be90172f163f666
Autor:
Anastasia Meshcheryakova, Martin Svoboda, Markus Jaritz, Felicitas Mungenast, Martina Salzmann, Dietmar Pils, Dan Cacsire Castillo-Tong, Gudrun Hager, Andrea Wolf, Elena Ioana Braicu, Jalid Sehouli, Sandrina Lambrechts, Ignace Vergote, Sven Mahner, Peter Birner, Philip Zimmermann, David N. Brindley, Georg Heinze, Robert Zeillinger, Diana Mechtcheriakova
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 537-560 (2019)
The sphingolipid and lysophosphatidate regulatory networks impact diverse mechanisms attributed to cancer cells and the tumor immune microenvironment. Deciphering the complexity demands implementation of a holistic approach combined with higher-resol
Externí odkaz:
https://doaj.org/article/e6d93a2a27b742b9970f8c7b17126477
Autor:
Mandy Stanske, Stephan Wienert, Dan Cacsire Castillo-Tong, Caroline Kreuzinger, Ignace Vergote, Sandrijne Lambrechts, Hani Gabra, Charlie Gourley, Ram N. Ganapathi, Ivonne Kolaschinski, Jan Budczies, Jalid Sehouli, Ilary Ruscito, Carsten Denkert, Hagen Kulbe, Wolfgang Schmitt, Korinna Jöhrens, Ioana Braicu, Silvia Darb-Esfahani
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 3, Pp 280-288 (2018)
PURPOSE: Tumor-infiltrating lymphocytes (TILs) have an established impact on the prognosis of high-grade serous ovarian carcinoma (HGSOC), however, their role in recurrent ovarian cancer is largely unknown. We therefore systematically investigated TI
Externí odkaz:
https://doaj.org/article/091df4cf64f94db9bd748c3369ed3a63
Autor:
Karina Piatek, Andrzej Kutner, Dan Cacsire Castillo-Tong, Teresa Manhardt, Nadja Kupper, Urszula Nowak, Michał Chodyński, Ewa Marcinkowska, Enikö Kallay, Martin Schepelmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 172 (2021)
Background: Ovarian cancer (OC) is one of the most lethal cancers in women. The active form of vitamin D3, 1,25-dihydroxyvitamin D3 (1,25D3, calcitriol) has anticancer activity in several cancers, including ovarian cancer, but the required pharmacolo
Externí odkaz:
https://doaj.org/article/d27c74a8aba943d0bc9430f8b7d57724
Autor:
Dan Cacsire Castillo-Tong, Charles Theillet, Els Berns, Stephan Polterauer, Reinhard Horvat, Georg Heinze, Fabian Trillsch, G. Bea A. Wisman, Hani Gabra, Diether Lambrechts, Bram Boeckx, Adriaan Vanderstichele, Ignace Vergote, Korinna Joehrens, Silvia Darb-Esfahani, Andrea Wolf, Julia Koller, Jalid Sehouli, Elena Ioana Braicu, Dominiek Smeets, Angelika Geroldinger, Caroline Kreuzinger
Supervised clustering of primary HGSOC (n=421) from the TCGA data using 59/126 immune related genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc0a86e5424f9f6fb05069d6112ea04
https://doi.org/10.1158/1078-0432.22462031.v1
https://doi.org/10.1158/1078-0432.22462031.v1
Autor:
Robert Brown, James Paul, Nadeem Siddiqui, Els MJJ Berns, G. Bea A. Wisman, Dan Cacsire Castillo-Tong, Caroline Kreuzinger, Ignace Vergote, Adriaan Vanderstichele, Silvia Darb-Esfahani, Jalid Sehouli, Elena Ioana Braicu, Hani Gabra, Paula Cunnea, Alexander Hergovich, Charlotte Wilhelm-Benartzi, Kirsty Flower, Erick Loomis, John Gallon, Nahal Masrour, Chail Koo, Angela Wilson, James M. Flanagan
Supplementary Figure S1: Clinical Study Schematic. Supplementary Figure S2: Significant changes in blood DNA methylation at time of ovarian cancer relapse compared to at presentation. Supplementary Figure S3: Methylation profiles of blood DNA at time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2c3d8cb8d3bc622340577f0aef3c7c
https://doi.org/10.1158/1078-0432.22463772.v1
https://doi.org/10.1158/1078-0432.22463772.v1
Autor:
Dan Cacsire Castillo-Tong, Charles Theillet, Els Berns, Stephan Polterauer, Reinhard Horvat, Georg Heinze, Fabian Trillsch, G. Bea A. Wisman, Hani Gabra, Diether Lambrechts, Bram Boeckx, Adriaan Vanderstichele, Ignace Vergote, Korinna Joehrens, Silvia Darb-Esfahani, Andrea Wolf, Julia Koller, Jalid Sehouli, Elena Ioana Braicu, Dominiek Smeets, Angelika Geroldinger, Caroline Kreuzinger
Purpose: Most high-grade serous ovarian cancer (HGSOC) patients develop recurrent disease after first-line treatment, frequently with fatal outcome. This work aims at studying the molecular biology of both primary and recurrent HGSOC.Experimental Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcf303c3ae596149416ac7ddb4f2765
https://doi.org/10.1158/1078-0432.c.6524981.v1
https://doi.org/10.1158/1078-0432.c.6524981.v1
Autor:
Dan Cacsire Castillo-Tong, Charles Theillet, Els Berns, Stephan Polterauer, Reinhard Horvat, Georg Heinze, Fabian Trillsch, G. Bea A. Wisman, Hani Gabra, Diether Lambrechts, Bram Boeckx, Adriaan Vanderstichele, Ignace Vergote, Korinna Joehrens, Silvia Darb-Esfahani, Andrea Wolf, Julia Koller, Jalid Sehouli, Elena Ioana Braicu, Dominiek Smeets, Angelika Geroldinger, Caroline Kreuzinger
Functional assignment of the 142 genes with the highest expression difference in the two clusters revealed by unsupervised clustering of recurrent samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c39900cbfa548e91b4d82c545ee86f4
https://doi.org/10.1158/1078-0432.22462019
https://doi.org/10.1158/1078-0432.22462019
Autor:
Robert Brown, James Paul, Nadeem Siddiqui, Els MJJ Berns, G. Bea A. Wisman, Dan Cacsire Castillo-Tong, Caroline Kreuzinger, Ignace Vergote, Adriaan Vanderstichele, Silvia Darb-Esfahani, Jalid Sehouli, Elena Ioana Braicu, Hani Gabra, Paula Cunnea, Alexander Hergovich, Charlotte Wilhelm-Benartzi, Kirsty Flower, Erick Loomis, John Gallon, Nahal Masrour, Chail Koo, Angela Wilson, James M. Flanagan
Purpose: DNA damage repair can lead to epigenetic changes. DNA mismatch repair proteins bind to platinum DNA adducts and at sites of DNA damage can recruit the DNA methylating enzyme DNMT1, resulting in aberrant methylation. We hypothesised that DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c46eabc66e9f93bbc183962695a5b3d
https://doi.org/10.1158/1078-0432.c.6525510.v1
https://doi.org/10.1158/1078-0432.c.6525510.v1