Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Dan C. McIntyre"'
Publikováno v:
Synapse. 75
The epileptogenic-prone (FAST) and epileptogenic-resistant (SLOW) rat strains have become a valuable tool for investigating neural plasticity. The strains were generated by breeding the rats that required the fewest amygdala stimulations to elicit a
Publikováno v:
Behavioral Neuroscience. 124:106-114
Caloric restriction (CR), primarily known for extending life span, has proven anticonvulsant in several seizure models and antiepileptogenic in a strain of inherently seizure susceptible mice. Our animal model consisted of a seizure-prone (Fast) stra
Autor:
Andrea M. Patey, Krista L. Gilby, Simon Sydserff, Dan C. McIntyre, Jennifer Jans, Victoria Thorne, Veronique St-Onge
Publikováno v:
Behavioral Neuroscience. 123:337-346
The creation of seizure-prone (Fast) and seizure-resistant (Slow) rat strains via selective breeding implies genetic control of relative seizure vulnerability, yet ample data also advocates an environmental contribution. To investigate potential envi
Autor:
Dan C. McIntyre, Dwayne Runke
Publikováno v:
Brain Research. 1240:143-152
Two rat lines bred for kindling susceptibility were previously observed to engage in different behavioral strategies in tests of emotionality. In order to extend past research on defensive behaviors in these strains which largely used males, Fast- an
Publikováno v:
Epilepsia. 48:1604-1613
Summary: Purpose: To determine whether low-frequency, 1Hz sine-wave stimulation (LFS) applied to a fully kindled amygdala focus would show antiepileptic properties in rats that were either naturally seizure prone (Fast) or seizure resistant (Slow). M
Publikováno v:
Behavioural Brain Research. 178:283-292
Rats selectively bred for "Fast" or "Slow" kindling epileptogenesis express different GABA(A) receptor subunits that may account for differences in their miniature inhibitory postsynaptic currents (mIPSCs). The neurosteroid tetrahydrodeoxycorticoster
Autor:
Craig E. Brown, Sherri L. Galasso, Richard H. Dyck, Dan C. McIntyre, G. Campbell Teskey, Corey Flynn
Publikováno v:
Neuroscience. 144:1409-1414
Zinc is released from a subset of cerebral cortical neurons whereupon it exerts a powerful modulatory influence on excitatory and inhibitory neurotransmission. A number of studies have suggested that alterations in the regulation of zinc may contribu
Publikováno v:
Epilepsy Research. 73:85-97
We used a multiple channel, single unit recording technique to investigate the neural activity in different corticolimbic and basal ganglia regions in freely moving rats before and during generalized amygdala kindled seizures. Neural activity was rec
Publikováno v:
Brain Pathology. 12:240-256
Symptomatic seizure disorders such as temporal lobe epilepsy are among the most prevalent and least medically responsive forms of epilepsy. They are also among the most interesting. A presumably normal individual receives some injurious stimuli, whic
Publikováno v:
Neuroscience. 140:1443-1451
Vagus nerve stimulation (VNS) is an adjunctive treatment for refractory epilepsy. Using a seizure-prone Fast-kindling rat strain with known comorbid behavioral features, we investigated the effects of VNS on spatial memory, epileptogenesis, kindled s