Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dan C. Maneval"'
Autor:
David Choi, Shiqi Li, Alex B. Blair, Dan C. Maneval, Jisook Lee, Jianxin Wang, Jonathan A. Pachter, Lei Zheng, Arsen Osipov, Mackenzie Henderson
Publikováno v:
Cancer Research. 80:1588-1588
Background: Pancreatic ductal adenocarcinoma (PDAC) is resistant to immunotherapy such as immune checkpoint inhibitors. One of the major resistance mechanisms is attributed to myeloid cells as an immunosuppressive element within the stroma of PDAC. I
Autor:
Samuel S. Dychter, Marie A. Printz, Gregory I. Frost, Dan C. Maneval, Richard I. Schiff, Lei Huang, Hans Peter Schwarz, Barry J. Sugarman, Douglas B. Muchmore, Fred H. Drake, Don A. Kennard, Sanna Rosengren, John Mcvey
Publikováno v:
The AAPS Journal
Recombinant human PH20 hyaluronidase (rHuPH20) is used to facilitate dispersion of subcutaneously delivered fluids and drugs. This report summarizes rHuPH20 immunogenicity findings from clinical trials where rHuPH20 was co-administered with SC human
Autor:
Fred H. Drake, Lei Huang, Don A. Kennard, Sanna Rosengren, Douglas B. Muchmore, Samuel S. Dychter, Dan C. Maneval, Barry J. Sugarman, Hans-Peter Schwarz, Richard I. Schiff, Marie A. Printz, Gregory I. Frost, John Mcvey
Publikováno v:
The AAPS Journal. 17:1523-1524
Erratum to: AAPS J DOI 10.1208/s12248-015-9782-0 Errors by the authors were inadvertently published in Table TableII and the supplemental material. The correct Table TableII is below and the corrected supplemental material can be found by acces
Autor:
Qiping Zhao, Gilbert A. Keller, Dan C. Maneval, Steve Rowe, Chunmei Zhao, Kim Phan, Michael Shepard, Ryan J. Osgood, Robert J. Connor, Lei Huang, Xiaoming Li, Gregory I. Frost, Curtis B. Thompson, Jason Parise, Sanna Rosengren, Christopher D. Thanos, Ge Wei, Jessica Cowell, Bob Veneziale
Publikováno v:
Cancer Research. 76:B32-B32
The epidermal growth factor (EGF) signaling pathway relies on recognition by its receptor, EGFR, and subsequent downstream signaling by the KRAS and BRAF proteins to relay proper proliferative, migratory, and angiogenic functions. Cancers with activa
Autor:
Dan C. Maneval, Renee Clift, Benjamin J. Thompson, Curtis B. Thompson, Christopher D. Thanos, Sanna Rosengren, Susan Zimmerman, Jennifer Souratha, Xiaoming Li, Barbara Blouw, Michael Shepard, Qiping Zhao
Publikováno v:
Cancer Research. 76:4886-4886
Hyaluronan (HA), a major extracellular matrix component in many solid tumors, has been proposed to contribute to tumor progression, and to play a complex role in T lymphocyte biology. Its depletion by intravenous PEGylated recombinant human hyaluroni