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Autor:
Dan Brobst, Brandy L. Paris, Florence Ndikum-Moffor, Etsuko Usuki, Andrew Parkinson, Jennifer Skibbe, Ivan King, Brian W. Ogilvie, Alaa-Eldin F Nassar, Lois J. Haupt, Rebecca Campbell
Publikováno v:
Drug Metabolism and Disposition. 37:1922-1930
Laromustine (VNP40101M, also known as Cloretazine) is a novel sulfonylhydrazine alkylating (anticancer) agent. Laromustine generates two types of reactive intermediates: 90CE and methylisocyanate. When incubated with rat, dog, monkey, and human liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f609c798bda1ce2ce5e1408090a5ac
https://doi.org/10.1124/dmd.109.027516
https://doi.org/10.1124/dmd.109.027516
