Hyperexpansion of RNA Bacteriophage Diversity.

Autor: Siddharth R Krishnamurthy, Andrew B Janowski, Guoyan Zhao, Dan Barouch, David Wang

Publikováno v: PLoS Biology, Vol 14, Iss 3, p e1002409 (2016)

Bacteriophage modulation of microbial populations impacts critical processes in ocean, soil, and animal ecosystems. However, the role of bacteriophages with RNA genomes (RNA bacteriophages) in these processes is poorly understood, in part because of

Externí odkaz: https://doaj.org/article/c3829d21f8ac409998039ed8cd31f3e1

Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study

Autor: Linda-Gail Bekker, Nigel Garrett, Ameena Goga, Lara Fairall, Tarylee Reddy, Nonhlanhla Yende-Zuma, Reshma Kassanjee, Shirley Collie, Ian Sanne, Andrew Boulle, Ishen Seocharan, Imke Engelbrecht, Mary-Ann Davies, Jared Champion, Tommy Chen, Sarah Bennett, Selaelo Mametja, Mabatlo Semenya, Harry Moultrie, Tulio de Oliveira, Richard John Lessells, Cheryl Cohen, Waasila Jassat, Michelle Groome, Anne Von Gottberg, Engelbert Le Roux, Kentse Khuto, Dan Barouch, Hassan Mahomed, Milani Wolmarans, Petro Rousseau, Debbie Bradshaw, Michelle Mulder, Jessica Opie, Vernon Louw, Barry Jacobson, Pradeep Rowji, Jonny G Peter, Azwi Takalani, Jackline Odhiambo, Fatima Mayat, Simbarashe Takuva, Lawrence Corey, Glenda E Gray, William Brumskine, Nivashnee Naicker, Disebo Makhaza, Vimla Naicker, Logashvari Naidoo, Elizabeth Spooner, Elane van Nieuwenhuizen, Kathryn Mngadi, Maphoshane Nchabeleng, James Craig Innes, Katherine Gill, Friedrich Georg Petrick, Shaun Barnabas, Sharlaa Badal-Faesen, Sheetal Kassim, Scott Hayden Mahoney, Erica Lazarus, Anusha Nana, Rebone Molobane Maboa, Philip Kotze, Johan Lombaard, Daniel Rudolf Malan, Sheena Kotze, Phuthi Mohlala, Amy Ward, Graeme Meintjes, Dorothea Urbach, Faeezah Patel, Andreas Diacon, Khatija Ahmed, Coert Grobbelaar, Pamela Mda, Thozama Dubula, Angelique Luabeya, Musawenkosi Bhekithemba Mamba, Lesley Burgess, Rodney Dawson

Publikováno v: The Lancet. 399:1141-1153

We aimed to assess the effectiveness of a single dose of the Ad26.COV2.S vaccine (JohnsonJohnson) in health-care workers in South Africa during two waves of the South African COVID-19 epidemic.In the single-arm, open-label, phase 3B implementation Si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a2b38d81813c084692f1aa09613fb9
https://doi.org/10.1016/s0140-6736(22)00007-1

Peripheral Blood Biomarkers in ART-Suppressed, SIV-Infected Rhesus Macaques Predict Viral Rebound Following ART Discontinuation

Autor: Dan Barouch, Malika Aid, Alessandro Colarusso, Victoria Walker-Sperling

The development of biomarkers that can predict viral rebound following discontinuation of antiretroviral therapy (ART) in HIV-1-infected humans would be an important advance in HIV-1 cure research. In a prior study, we initiated ART in 20 rhesus maca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ed3e8a33832dda0c0361e045468347c
https://doi.org/10.21203/rs.3.rs-1705099/v1

Erratum for the Research Article: 'Durability and correlates of vaccine protection against Zika virus in rhesus monkeys' by P. Abbink, R. A. Larocca, K. Visitsunthorn, M. Boyd, R. A. De La Barrera, G. D. Gromowski, M. Kirilova, R. Peterson, Z. Li, O. Nanayakkara, R. Nityanandam, N. B. Mercado, E. N. Borducchi, A. Chandrashekar, D. Jetton, S. Mojta, P. Gandhi, J. LeSuer, S. Khatiwada, M. G. Lewis, K. Modjarrad, R. G. Jarman, K. H. Eckels, S. J. Thomas, N. L. Michael, D. H. Barouch

Autor: Dan Barouch, Stephen Thomas, Abishek Chandrashekar

Publikováno v: Science Translational Medicine. 10

An effective Zika virus (ZIKV) vaccine will require long-term durable protection. Several ZIKV vaccine candidates have demonstrated protective efficacy in nonhuman primates, but such studies have typically involved ZIKV challenge shortly following va

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efae0652cc6ee7177e7632bbc7508db2
https://doi.org/10.1126/scitranslmed.aau6861

Peptide microarrays for coverage of sequence diversity in monitoring the B cell immune response (TECH2P.911)

Autor: Aaron Castro, Kathryn Stephenson, George Neubauer, Bette Korber, Dan Barouch, Nikolaus Pawlowski, Johannes Zerweck, Ulf Reimer

Publikováno v: The Journal of Immunology. 194:206.21-206.21

Pathogens such as HIV or other viruses exhibit considerable sequence diversity as a strategy to escape the host immune system. However, sequence diversity is not limited to infectious agents. The increasing application of DNA sequencing indicates div

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cbad90d8a1f0074a3a2371adb7bddd9
https://doi.org/10.4049/jimmunol.194.supp.206.21