Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dan Baeckström"'
Publikováno v:
Currents in Pharmacy Teaching and Learning. 11:433-449
Introduction For some time, our faculty have expressed concerns regarding an apparent decrease in pharmacy students' academic productivity and performance. This study aimed to elucidate present conditions and suggest suitable interventions to improve
Publikováno v:
International Journal of Oncology
Recent research into the mechanisms of tumour cell invasiveness has highlighted the parallels between carcinogenesis and epithelial-mesenchymal transition (EMT), originally described as a developmental transdifferentiation program but also implicated
Publikováno v:
Experimental Cell Research. 307:259-275
Signalling from the growth factor receptor subunit and proto-oncogene c-erbB2 has been shown to inhibit the adhesive function of the collagen receptor integrin α 2 β 1 in human mammary epithelial cells. This anti-adhesive effect is mediated by the
Autor:
Christian X. Andersson, Anu Sikut, Sirle Laos, Dan Baeckström, Gunnar C. Hansson, Julia Fernandez-Rodriguez, Rein Sikut
Publikováno v:
Biochemical and Biophysical Research Communications. 316:12-17
CD43 is a transmembrane molecule with a highly O-glycosylated extracellular domain of mucin type. It is a normal constituent of leukocytes and found in colon adenoma, but not in normal colon epithelia. Here it is shown that the cytoplasmic tail of CD
Publikováno v:
Journal of Cell Science. 111:521-532
The HB2 cell line, developed from luminal epithelial cells cultured from milk, forms ball-like structures in collagen gels which show a uniform branching response to hepatocyte growth factor. The alpha2beta1 integrin is the major integrin expressed b
Publikováno v:
Biochemical and Biophysical Research Communications. 238:612-616
CD43 (leukosialin) has hitherto been considered as an exclusive leukocyte marker, but now we report the expression of CD43 in the epithelial cells of all studied colorectal adenomas (21/21) and in about 50% (18/34) of adenocarcinomas as analyzed both
Autor:
Dan Baeckström
Publikováno v:
Journal of Biological Chemistry. 272:11503-11509
This paper describes the biosynthesis of L-CanAg, a mucin-like glycoprotein which carries the carcinoma-associated carbohydrate epitope sialyl-Lewis a and is secreted by the colon adenocarcinoma cell line COLO 205. Recently, it has been shown that L-
Autor:
Dan Baeckström, Gunnar C. Hansson
Publikováno v:
Glycoconjugate Journal. 13:833-837
RNA from four colorectal carcinoma cell lines was prepared and analysed in Northern blots using probes for the MUC2, MUC4, and MUC5AC mucin apoprotein genes. The sizes of the transcripts were very large, in the order of at least 12-16 kb. The presenc
Publikováno v:
Journal of Biological Chemistry. 270:13688-13692
The colon adenocarcinoma cell line COLO 205 secretes L-CanAg, a mucin-like glycoprotein carrying the carcinoma-associated sialyl-Lewis a carbohydrate epitope. In an attempt to identify its apoprotein, an NH2-terminal peptide sequence was obtained fro
Publikováno v:
Journal of Biological Chemistry. 269:14430-14437
Purification of sialyl-Le(a)-carrying mucins from primary human bile by trichloroacetic acid precipitation, delipidation, and gel filtration in guanidinium chloride gave three separable fractions, one of which was further purified by affinity chromat