Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dan A. Chiche"'
Autor:
Andrew Griffin, Stuart Hossack, Richard L. Leff, Dan A. Chiche, Philippe Walker, Roxane Aubray, William Brown
Publikováno v:
The Journal of Pain. 18:726-738
Most previous transient receptor potential vanilloid subtype 1 (TRPV1) antagonist programs have been put on hold, mainly because of on-target adverse events: hyperthermia and impaired noxious heat sensation. NEO6860 is a TRPV1 antagonist, blocking ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806a7f330d119b3e0ec9c141e25ea1af
https://doi.org/10.1016/j.jpain.2017.01.009
https://doi.org/10.1016/j.jpain.2017.01.009
Autor:
Margit Solymár, Donald J. Kyle, Zsolt Szakács, András Garami, Robson Cristiano Lillo Vizin, Nelli Farkas, Wade D. Van Horn, Dan A. Chiche, Ram P. Kapil, Yury P. Shimansky, Zoltan Rumbus, Judit Hegyi, Andrej A. Romanovsky, Alexandra Csenkey, Péter Hegyi
Publikováno v:
Pharmacology & Therapeutics. 208:107474
Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. TRPV1 can be activated by caps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926906e86aa7a9437758f61c0d10181a
https://doi.org/10.1016/j.pharmthera.2020.107474
https://doi.org/10.1016/j.pharmthera.2020.107474
Autor:
Richard L. Leff, Jeffrey Miller, Philippe Walker, Pierre Arsenault, Roi Treister, Nathaniel P. Katz, William Brown, Dan A. Chiche
Publikováno v:
Pain Reports
PAIN Reports, Vol 3, Iss 6, p e696 (2018)
PAIN Reports, Vol 3, Iss 6, p e696 (2018)
Introduction:. NEO6860 is a TRPV1 antagonist when activated by capsaicin but not by heat or pH, developed to relieve pain without the adverse events reported with non–modality-selective TRPV1 antagonists. Objective:. The primary Objective of this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9acd6d6a60b2de090907625c9b0a57b
http://europepmc.org/articles/PMC6344137
http://europepmc.org/articles/PMC6344137
Publikováno v:
The Journal of Pain. 17:S79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1a8f3616f8cd610927e7212289f71a7
https://doi.org/10.1016/j.jpain.2016.01.397
https://doi.org/10.1016/j.jpain.2016.01.397
Autor:
Xiaoyuan Jiang
This volume outlines the origins of a wide range of disciplines including astronomy, agricultural science, medicine, physics, chemistry, and natural history. It provides an overview of China's history of science and technology, which can be traced ba
