Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Dan‑Yun Ruan"'
Publikováno v:
Cancer Communications, Vol 44, Iss 1, Pp 3-22 (2024)
Abstract In recent years, remarkable breakthroughs have been reported on antibody‐drug conjugates (ADCs), with 15 ADCs successfully entering the market over the past decade. This substantial development has positioned ADCs as one of the fastest‐g
Externí odkaz:
https://doaj.org/article/8dccdbbcec754aab923da06739da0833
Autor:
Yun‐Yun Xu, Ting Li, Ao Shen, Xiao‐Qiong Bao, Jin‐Fei Lin, Li‐Zhen Guo, Qi Meng, Dan‐Yun Ruan, Qi‐Hua Zhang, Zhi‐Xiang Zuo, Zhao‐lei Zeng
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Epstein‒Barr virus‐associated gastric cancer (EBVaGC) is regarded as a distinct molecular subtype of GC, accounting for approximately 9% of all GC cases. Clinically, EBVaGC patients are found to have a significantly lower freq
Externí odkaz:
https://doaj.org/article/3e9a40ea87244b2e9c7df254e98393d9
Autor:
Qi Meng, Yun-Xin Lu, Dan-Yun Ruan, Kai Yu, Yan-Xing Chen, Min Xiao, Yun Wang, Ze-Xian Liu, Rui-Hua Xu, Huai-Qiang Ju, Miao-Zhen Qiu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss , Pp 695-710 (2021)
Growing evidence implies a link between DNA methylation and tumor immunity/immunotherapy. However, the global influence of DNA methylation on the characteristics of the tumor microenvironment and the efficacy of immunotherapy remains to be clarified.
Externí odkaz:
https://doaj.org/article/e406e01926b84f209905e5f59f87e2ac
Autor:
Tian-Tian Wang, Qing-Hua Cao, Ming-Yuan Chen, Qing Xia, Xin-Juan Fan, Xiao-Kun Ma, Qu Lin, Chang-Chang Jia, Min Dong, Dan-Yun Ruan, Ze-Xiao Lin, Jing-Yun Wen, Li Wei, Xing Li, Zhan-Hong Chen, Lei Wang, Xiang-Yuan Wu, Xiang-Bo Wan
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80317 (2013)
Autophagy can be tumor suppressive as well as promotive in regulation of tumorigenesis and disease progression. Accordingly, the prognostic significance of autophagy key regulator Beclin 1 was varied among different tumors. Here, we detected the clin
Externí odkaz:
https://doaj.org/article/adc78059c4f140c09588ea933c85aa77
Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc
Autor:
Ying-Nan Wang, Dan-Yun Ruan, Zi-Xian Wang, Kai Yu, Dai-Lin Rong, Ze-Xian Liu, Feng Wang, Jia-Jia Hu, Ying Jin, Qi-Nian Wu, Heng-Ying Pu, Min Wang, Rui-Hua Xu, Zhao-Lei Zeng
Publikováno v:
Oncogene. 41:5266-5278
Dysregulated cholesterol metabolism is a hallmark of colorectal cancer (CRC). However, the usage of cholesterol-lowering agents seemed to have no benefit in CRC patients. In this study, we focused on the cholesterol-nuclear receptors (NRs) axis as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddab9c70682bd8d0393e220c408e720
https://doi.org/10.1038/s41388-022-02515-3
https://doi.org/10.1038/s41388-022-02515-3
Autor:
Yun-Yun Xu, Ting Li, Ao Shen, Xiao-Qiong Bao, Jin-Fei Lin, Li-Zhen Guo, Qi Meng, Dan-Yun Ruan, Qi-Hua Zhang, Zhi-Xiang Zuo, Zhao-lei Zeng
Background: Epstein‒Barr virus-associated gastric cancer (EBVaGC) is regarded as a distinct molecular subtype of GC, accounting for approximately 9% of all GC cases, and it often exhibits unique molecular features and clinicopathological characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::552356c5d11431dd33e2e2b0f254a7ae
https://doi.org/10.21203/rs.3.rs-2593808/v1
https://doi.org/10.21203/rs.3.rs-2593808/v1
Autor:
Kai Yu, Qi Zhao, Qi Meng, Rui-Hua Xu, Yang Li, Long Bai, Zexian Liu, Ting Li, Huai-Qiang Ju, Junzhong Lin, Min Wang, Dan-Yun Ruan, De Shen Wang, Xiang-Yuan Wu, Li-Zhi Luo, Ying-Nan Wang, Jin-Fei Lin
Publikováno v:
Oncogene
Fat mass and obesity-associated protein (FTO), an N6-methyladenosine (m6A) demethylase, participates in tumor progression and metastasis in many malignancies, but its role in colorectal cancer (CRC) is still unclear. Here, we found that FTO protein l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6237619eecaac05300f161964cdf25e0
http://europepmc.org/articles/PMC8376648
http://europepmc.org/articles/PMC8376648
Autor:
Huai-Qiang Ju, Kai Yu, Min Xiao, Yun-Xin Lu, Qi Meng, Yan-Xing Chen, Yun Wang, Rui-Hua Xu, Zexian Liu, Dan-Yun Ruan, Miao Zhen Qiu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 24, Iss, Pp 695-710 (2021)
Growing evidence implies a link between DNA methylation and tumor immunity/immunotherapy. However, the global influence of DNA methylation on the characteristics of the tumor microenvironment and the efficacy of immunotherapy remains to be clarified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03895af66d16bd2ff68323d1c793e185
http://www.sciencedirect.com/science/article/pii/S2162253121000950
http://www.sciencedirect.com/science/article/pii/S2162253121000950
Publikováno v:
World Journal of Clinical Cases
BACKGROUND Mesenchymal tumors such as perivascular epithelioid cell neoplasm (PEComa) and inflammatory pseudotumor-like follicular dendritic cell sarcoma (IPT-like FDC sarcoma) are relatively uncommon in the liver and are particularly rare in the cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d085647f68ed1d50f9c4d5abba71ab5e
https://doi.org/10.12998/wjcc.v7.i20.3194
https://doi.org/10.12998/wjcc.v7.i20.3194
Autor:
Chang-Chang Jia, Tian-Tian Wang, J.-T. Cheng, Dan-Yun Ruan, Huiqiang Huang, Zhi-Huan Lin, Xiaocai Wu
Publikováno v:
Clinical and Translational Oncology. 22:370-380
As a novel immune-nutritional biomarker, the controlling nutritional status (CONUT) score has been reported to predict outcomes in cancer patients. We aimed to elucidate the prognostic value of preoperative CONUT score and construct a CONUT score-bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36a0a23917c2f3035c312f7e3ea4ffb
https://doi.org/10.1007/s12094-019-02137-4
https://doi.org/10.1007/s12094-019-02137-4