Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Danúbia Bonfanti dos Santos"'
Autor:
Danúbia Bonfanti dos Santos, Gabriela Cristina de Paula, Eduardo Luiz Gasnhar Moreira, Andreza Fabro de Bem, Marcelo Farina, Jadna Bogado Lopes, Jade de Oliveira, Daiane Fátima Engel
Publikováno v:
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
Journal of Alzheimer's Disease
Universidade de Brasília (UnB)
instacron:UNB
Journal of Alzheimer's Disease
Background: Evidence has revealed an association between familial hypercholesterolemia and cognitive impairment. In this regard, a connection between cognitive deficits and hippocampal blood-brain barrier (BBB) breakdown was found in low-density lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb8d51f1bd6be8fff1cc9c11cc512e2
https://repositorio.unb.br/handle/10482/42136
https://repositorio.unb.br/handle/10482/42136
Autor:
Marcelo Farina, Guilherme Razzera, Jean Pierre Oses, Mariana Appel Hort, Dirleise Colle, Danúbia Bonfanti dos Santos, Eduardo Luiz Gasnhar Moreira, Karin dos Santos, Alessandra Antunes dos Santos
Publikováno v:
Molecular neurobiology. 57(8)
Experimental evidence has shown that probucol, a hypocholesterolemic agent, is also able to increase glutathione peroxidase (GPx) activity. However, there is a lack of knowledge about the mechanism(s) involved in this event. In this study, in vitro e
Autor:
Dirleise Colle, Heloisa Ghizoni, Fernando Barbosa, Aline Aita Naime, Cinara Ludvig Gonçalves, Viviane de Souza, Mark William Lopes, Marina Ventura, Vanessa Cristina de Oliveira Souza, Juliana Montagna Hartwig, Marcelo Farina, Patricia S. Brocardo, Danúbia Bonfanti dos Santos
Publikováno v:
Food and Chemical Toxicology. 120:603-615
Fish and shellfish, which represent important sources of nutrients (i.e., n-3 fatty acids), can contain significant amounts of methylmercury (MeHg), a neurotoxic compound. We investigated the potential neuroprotective effects of perinatal treatment w
Autor:
Heloisa Ghizoni, Marcelo Farina, Mariana Appel Hort, Dirleise Colle, Aline Aita Naime, Cinara Ludvig Gonçalves, Danúbia Bonfanti dos Santos
Publikováno v:
Neurotoxicity research. 37(1)
Exposure to environmental contaminants represents an important etiological factor in sporadic Parkinson’s disease (PD). It has been reported that PD could arise from events that occur early in development and that lead to delayed adverse consequenc
Autor:
Mariana Appel Hort, Dirleise Colle, Paulo Fernando Dias, Aline Aita Naime, Cinara Ludvig Gonçalves, Renata Pietsch Ribeiro, Heloisa Ghizoni, Danúbia Bonfanti dos Santos, Marcelo Godoi, Marcelo Farina, Antonio L. Braga
Publikováno v:
Behavioural Brain Research. 305:30-36
Bradykinesia and hypokinesia represent well-known motor symptoms of Parkinson's disease (PD). While bradykinesia (slow execution of movements) is present in less affected PD patients and aggravates as the disease severity increases, hypokinesia (redu
Autor:
Jamil Assreuy, Mariana Appel Hort, Dirleise Colle, Patrick P. Michel, Danúbia Bonfanti dos Santos, Rita Raisman-Vozari, Marcelo Godoi, Rui Daniel Prediger, Gael Le Douaron, Marcelo Farina, Eduardo Luiz Gasnhar Moreira, Antonio L. Braga
Publikováno v:
Molecular Neurobiology. 54:1513-1530
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by non-motor and motor disabilities. This study investigated whether succinobucol (SUC) could mitigate nigrostriatal injury caused by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrah
Autor:
Luiz Felipe de Souza, Mariana Figueiroa Uchoa, Rodrigo B. Leal, Tanara V. Peres, Danúbia Bonfanti dos Santos, Alcir Luiz Dafre, Marcelo Farina, Danielle Ferraz Mello
Publikováno v:
Cellular and Molecular Neurobiology. 36:1015-1022
α-Tocopheryl phosphate (αTP) is a phosphorylated form of α-tocopherol. Since it is phosphorylated in the hydroxyl group that is essential for the antioxidant property of α-tocopherol, we hypothesized that αTP would modulate the antioxidant syste
Autor:
Dirleise Colle, Danúbia Bonfanti dos Santos, Patricia S. Brocardo, Marcelo Farina, Viviane de Souza, Rodrigo B. Leal, Mark William Lopes
Publikováno v:
Molecular biology reports. 46(1)
Selenium (Se) is an essential trace element for humans; its intake is needed to allow the proper synthesis of 25 different selenoproteins that are necessary to the normal functioning of several organs, including the brain. Accordingly, decreased Se l
Autor:
Dirleise Colle, Najeh Maissar Khalil, Eduardo Luiz Gasnhar Moreira, Danúbia Bonfanti dos Santos, Rui Daniel Prediger, Marcelo Farina, Rubiana Mara Mainardes, Gabriela da Rocha Lindner
Publikováno v:
Nanomedicine. 10:1127-1138
Aim: This study investigated the neuroprotective effects of resveratrol (RVT)-loaded polysorbate 80 (PS80)-coated poly(lactide) nanoparticles in a mouse model of Parkinson's disease (PD), and compared these effects with those from bulk RVT. Methods:
Autor:
Rui Daniel Prediger, Alcir Luiz Dafre, CinaraLudvig Gonçalves, Viviane de Souza, Marcelo Farina, Patricia S. Brocardo, Aline Aita Naime, Josiel Mileno Mack, Sthéfani Spricigo Portilho, Heloisa Ghizoni, Mark William Lopes, Danúbia Bonfanti dos Santos
Publikováno v:
Neurochemical research. 43(3)
Systemic inflammation triggered by lipopolysaccharide (LPS) administration disrupts blood–brain barrier (BBB) homeostasis in animal models. This event leads to increased susceptibility of several encephalic structures to potential neurotoxicants pr