Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Damon Sutton"'
Autor:
Zayna Nahas, Christine Matheson, Branden Reid, Joyce Axelman, Jennifer H. Elisseeff, Shimon Unterman, Damon Sutton, Alexander Hillel, Jennifer Petsche
Publikováno v:
Dermatologic Surgery. 38:471-478
Background Rigorous preclinical testing of soft tissue fillers has been lacking. No animal model has emerged as an accepted standard to evaluate tissue filler longevity. Objective To validate a small animal model to compare soft tissue filler degrada
Publikováno v:
Experimental Biology and Medicine. 232:1090-1099
Polymer micelles with two different core-forming blocks, poly(d,l -lactide) (PLA) and poly(ε-caprolactone) (PCL), but the same coronal material, poly(ethylene glycol) (PEG), were investigated in this study as nanoscopic drug carriers. The release of
Publikováno v:
Pharmaceutical Research. 24:1029-1046
Polymer micelles are rapidly becoming a powerful nanomedicine platform for cancer therapeutic applications due to their small size (10-100 nm), in vivo stability, ability to solubilize water insoluble anticancer drugs, and prolonged blood circulation
Autor:
Konstantin Leskov, Xintao Shuai, Damon Sutton, Jinming Gao, João Trindade Marques, David A. Boothman, Bryan R.G. Williams, Saejeong Kim
Publikováno v:
International Journal of Nanomedicine
Small interfering RNA molecules (siRNA) hold great promise to specifically target cytoprotective factors to enhance cancer therapy. Like antisense RNA strategies, however, the use of siRNA is limited because of in vivo instability. As a first step to
Poly(D,L-lactide-co-glycolide)/poly(ethylenimine) blend matrix system for pH sensitive drug delivery
Publikováno v:
Journal of Applied Polymer Science. 100:89-96
Poly(d,l-lactide-co-glycolide) (PLGA) and poly(ethylenimine) (PEI) were blended and found to form a homogeneous pH sensitive matrix for drug release. Differ- ential scanning calorimetry (DSC) studies of the PLGA/PEI blends showed a single glass trans
Publikováno v:
Journal of Controlled Release. 83:427-435
This paper describes a combined modeling and experimental approach for the design and development of a polymer device to provide local drug therapy to thermally ablated solid tumors. The polymer device, in the shape of cylindrical millirod, will be i
Autor:
Zayna Nahas, Shimon Unterman, Alexander T. Hillel, Serge Lichtsteiner, Jeannine M. Coburn, Janis M. Taube, Susumu Mori, Patricia Walker, Zhipeng Hou, Nathaniel David, Je-Min Chae, Joyce Axelman, Andrew S. Thomas, Branden Reid, Christine Matheson, Qiongyu Guo, Robert K.G. Trow, Damon Sutton, Jennifer H. Elisseeff
Publikováno v:
Science Translational Medicine. 3
Soft tissue reconstruction often requires multiple surgical procedures that can result in scars and disfiguration. Facial soft tissue reconstruction represents a clinical challenge because even subtle deformities can severely affect an individual’s
Autor:
Elvin Blanco, Damon Sutton, Jinming Gao, Brent D. Weinberg, David A. Boothman, Ying Dong, Erik A. Bey
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 122(3)
Beta-lapachone (beta-lap) is a novel anticancer agent that is bioactivated by NADP(H): quinone oxidoreductase 1 (NQO1), an enzyme overexpressed in a variety of tumors. Despite its therapeutic promise, the poor aqueous solubility of beta-lap hinders i
Publikováno v:
Pharmaceutical Research; Jun2007, Vol. 24 Issue 6, p1029-1046, 18p
Publikováno v:
Journal of Applied Polymer Science; Apr2006, Vol. 100 Issue 1, p89-96, 8p