Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Damon J. Kelly"'
Autor:
Stephen F. Badylak, Paul V. Kochupura, Ira S. Cohen, Sergey V. Doronin, Adam E. Saltman, Thomas W. Gilbert, Damon J. Kelly, Ronald A. Ignotz, Glenn R. Gaudette
Publikováno v:
Cell Transplantation, Vol 15 (2006)
Regenerative medicine approaches for the treatment of damaged or missing myocardial tissue include cell-based therapies, scaffold-based therapies, and/or the use of specific growth factors and cytokines. The present study evaluated the ability of ext
Externí odkaz:
https://doaj.org/article/468d5abe15124e7f8428f738a21b4e58
Autor:
Sergey V. Doronin, Adam J.T. Schuldt, Glenn R. Gaudette, Paul V. Kochupura, Ira S. Cohen, Damon J. Kelly, Irina A. Potapova, Amy B. Rosen, Stephen F. Badylak, Evren U. Azeloglu, Peter R. Brink
Publikováno v:
Tissue Engineering Part A. 15:2189-2201
During the past few years, studies involving the implantation of stem cells, chemical factors, and scaffolds have demonstrated the ability to augment the mammalian heart's native regenerative capacity. Scaffolds comprised of extracellular matrix (ECM
Autor:
Michael R. Rosen, Zhongju Lu, Richard B. Robinson, Damon J. Kelly, Ira S. Cohen, Sergey V. Doronin, Irina A. Potapova, Amy B. Rosen, Paul V. Kochupura, Adam J.T. Schuldt, Peter R. Brink, Glenn R. Gaudette
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 295:H2257-H2263
The need to regenerate tissue is paramount, especially for the heart that lacks the ability to regenerate after injury. The urinary bladder extracellular matrix (ECM), when used to repair a right ventricular defect, successfully regenerated some mech
Autor:
Richard Z. Lin, Zhongju Lu, Li Wan, Ira S. Cohen, Lisa M. Ballou, Damon J. Kelly, Ya-Ping Jiang
Publikováno v:
Journal of Biological Chemistry. 281:29988-29992
For many patients with cardiac insufficiency, the disease progresses inexorably to organ dilatation, pump failure, and death. Although there are examples of reversible heart failure in man, our understanding of how the myocardium repairs itself is li
Autor:
Glenn R. Gaudette, Paul V. Kochupura, Adam E. Saltman, Sergey V. Doronin, Ira S. Cohen, Thomas W. Gilbert, Damon J. Kelly, Stephen F. Badylak, Ronald A. Ignotz
Publikováno v:
Cell Transplantation, Vol 15 (2006)
Regenerative medicine approaches for the treatment of damaged or missing myocardial tissue include cell-based therapies, scaffold-based therapies, and/or the use of specific growth factors and cytokines. The present study evaluated the ability of ext
Autor:
Damon J. Kelly, Ya-Ping Jiang, Lisa M. Ballou, Zhongju Lu, Ira S. Cohen, Joan Zuckerman, Dwight W. Martin, Gaofeng Fan, Richard Z. Lin
Publikováno v:
Journal of Biological Chemistry. 280:40337-40346
Receptors coupled to Galpha q play a key role in the development of heart failure. Studies using genetically modified mice suggest that Galpha q mediates a hypertrophic response in cardiac myocytes. Galpha q signaling in these models is modified duri
Autor:
Peter R. Brink, Ira S. Cohen, Richard B. Robinson, Irina A. Potapova, Adam J.T. Schuldt, Jia Lu, Michael R. Rosen, Kyle J. Robichaud, Sergey V. Doronin, Glenn R. Gaudette, Amy B. Rosen, Damon J. Kelly
Publikováno v:
Stem cells (Dayton, Ohio). 25(8)
Stem cells show promise for repair of damaged cardiac tissue. Little is known with certainty, however, about the distribution of these cells once introduced in vivo. Previous attempts at tracking delivered stem cells have been hampered by the autoflu
Autor:
Peter R. Brink, Zhongju Lu, Sergey V. Doronin, Yuanjian Guo, Ira S. Cohen, Michael R. Rosen, Glenn R. Gaudette, Adam J.T. Schuldt, Amy B. Rosen, Richard B. Robinson, Irina A. Potapova, Paul V. Kochupura, Damon J. Kelly
Publikováno v:
Journal of electrocardiology. 40
Heart failure survival after diagnosis has barely changed for more than half a century. Recently, investigation has focused on differentiation of stem cells in vitro and their delivery for use in vivo as replacement cardiac contractile elements. Here
Autor:
Ya-Ping, Jiang, Lisa M, Ballou, Zhongju, Lu, Li Wan, Damon J, Kelly, Ira S, Cohen, Richard Z, Lin
Publikováno v:
The Journal of biological chemistry. 281(40)
For many patients with cardiac insufficiency, the disease progresses inexorably to organ dilatation, pump failure, and death. Although there are examples of reversible heart failure in man, our understanding of how the myocardium repairs itself is li
Autor:
Paul V. Kochupura, Evren U. Azeloglu, Glenn R. Gaudette, Damon J. Kelly, Irvin B. Krukenkamp, Ira S. Cohen, Sergey V. Doronin, Stephen F. Badylak
Publikováno v:
Circulation. 112
Background— Extracellular matrix (ECM), a tissue-engineered scaffold, recently demonstrated cardiomyocyte population after myocardial implantation. Surgical restoration of myocardium frequently uses Dacron as a myocardial patch. We hypothesized tha