Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Damini Chand"'
Autor:
Zhen Zhang, Jinyan Liu, Chaoqi Zhang, Feng Li, Lifeng Li, Dan Wang, Damini Chand, Fangxia Guan, Xingxing Zang, Yi Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
HHLA2, a newly identified B7 family member, regulates T cell functions. However, the expression and prognostic value of HHLA2 in solid tumors is ill defined. This study aimed to reveal the expression landscape of HHLA2 in various solid tumors, and to
Externí odkaz:
https://doaj.org/article/08c8b860f63349358b326b236809caae
Autor:
Damini Chand, Yasuo Yamazaki, Kristina Ruuth, Christina Schönherr, Tommy Martinsson, Per Kogner, Edward F. Attiyeh, John Maris, Olena Morozova, Marco A. Marra, Miki Ohira, Akira Nakagawara, Per-Erik Sandström, Ruth H. Palmer, Bengt Hallberg
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 373-382 (2013)
SUMMARY Neuroblastoma is a childhood extracranial solid tumour that is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the anaplastic lymphoma kinase (ALK) receptor tyrosine kin
Externí odkaz:
https://doaj.org/article/f61c5b972ea944289363faff0ad11f9f
Autor:
Xiaoxin Ren, Juan Lin, Deepika Dhawan, Alexander Sankin, Xingxing Zang, Mark P. Schoenberg, Damini Chand, Suraj Pursnani, Deborah W. Knapp
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Canine bladder cancer provides a novel model system for the study of invasive human urothelial carcinoma. The immunobiology of canine tumors is largely unknown. We repor...
Autor:
Damini Chand, Deepika Dhawan, Mark P. Schoenberg, Xingxing Zang, Juan Lin, Xiaoxin Ren, Alexander Sankin, Deborah W. Knapp
Publikováno v:
Bladder Cancer (Amsterdam, Netherlands)
Background: B7x (B7-H4/B7S1/VTCN1), an inhibitory immune checkpoint molecule is a potential therapeutic target owing to its immunosuppressive effect and well-known expression in cancers. Immune checkpoints in canine bladder cancer are largely undefin
Publikováno v:
Cancer Research. 80:A17-A17
Purpose: To identify new pharmacologically targetable immune checkpoints in pediatric Hodgkin lymphoma. Background: The role of PD-1/PD-L1 axis in Hodgkin lymphoma (HL) has led to FDA approval for use of inhibitors of this pathway in chemotherapy-ref
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 37:810.e1-810.e5
Background High T-cell receptor (TCR) repertoire clonality is associated with clinical response to immune checkpoint blockade in bladder cancer. Objective To determine if TCR repertoire is more clonal in tumors than in benign inflammation. Methods We
Publikováno v:
Journal of Urology. 199
Autor:
Hallberg, Jikui Guan, Yasuo Yamazaki, Damini Chand, Jesper Van Dijk, Kristina Ruuth, Ruth Palmer, Bengt
Publikováno v:
Cancers; Volume 9; Issue 11; Pages: 149
Numerous mutations have been observed in the Anaplastic Lymphoma Kinase (ALK) receptor tyrosine kinase (RTK) in both germline and sporadic neuroblastoma. Here, we have investigated the Y1278S mutation, observed in four patient cases, and its potentia
Autor:
Jianmin Wu, Christina Schönherr, Ganesh Umapathy, James R. Fuchs, Kristina Ruuth, Barbara Witek, Roger J. Daly, Ruth H. Palmer, Pui-Kai Li, Kamaraj Sattu, Damini Chand, Falko Hochgräfe, Fredrik Hugosson, Bengt Hallberg
Publikováno v:
The Febs Journal
Activation of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase is a key oncogenic mechanism in a growing number of tumor types. In the majority of cases, ALK is activated by fusion with a dimerizing partner protein as a result of chromos
Autor:
Marco A. Marra, Bengt Hallberg, Per Kogner, Tommy Martinsson, Edward F. Attiyeh, Akira Nakagawara, Yasuo Yamazaki, Christina Schönherr, Miki Ohira, John M. Maris, Per-Erik Sandström, Kristina Ruuth, Damini Chand, Olena Morozova, Ruth H. Palmer
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 373-382 (2013)
Disease Models & Mechanisms
Disease Models & Mechanisms
SummaryNeuroblastoma is a childhood extracranial solid tumor which is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the Anaplastic Lymphoma Kinase (ALK) receptor tyrosine kina