Zobrazeno 1 - 10
of 506
pro vyhledávání: '"Damijan, Miklavčič"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Electric pulses used in electroporation-based treatments have been shown to affect the excitability of muscle and neuronal cells. However, understanding the interplay between electroporation and electrophysiological response of excitable cel
Externí odkaz:
https://doaj.org/article/4736a2f599ba4092b5049d7f64e4f49d
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
IntroductionIn modern times, bacterial infections have become a growing problem in the medical community due to the emergence of antibiotic-resistant bacteria. In fact, the overuse and improper disposal of antibiotics have led to bacterial resistance
Externí odkaz:
https://doaj.org/article/e8a3205bb3e74e5483a9e7ca4d4de91d
Publikováno v:
Zdravniški Vestnik, Vol 91, Iss 11-12, Pp 483-495 (2022)
Povečano prepustnost celične membrane zaradi izpostavitve celic oz. tkiv električnemu polju imenujemo elektroporacija. Povzroči vrsto sprememb v celici, od strukturnih in kemijskih sprememb v celični membrani, strukturnih sprememb proteinov oz.
Externí odkaz:
https://doaj.org/article/2893b57ea1d640a0a90b8079e36d6a7e
Publikováno v:
Applied Sciences, Vol 14, Iss 7, p 2695 (2024)
Pulsed field ablation (PFA) is a promising new treatment for atrial fibrillation (AF), in which pulmonary vein isolation is achieved by irreversible electroporation. Electroporation causes ATP to leak through the permeabilized membrane. ATP is requir
Externí odkaz:
https://doaj.org/article/ed892143f4b64bbbabd6fa2269e8ad6d
Autor:
Bor Kos, Lars Mattison, David Ramirez, Helena Cindrič, Daniel C. Sigg, Paul A. Iaizzo, Mark T. Stewart, Damijan Miklavčič
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionPulsed field ablation is an emerging modality for catheter-based cardiac ablation. The main mechanism of action is irreversible electroporation (IRE), a threshold-based phenomenon in which cells die after exposure to intense pulsed electr
Externí odkaz:
https://doaj.org/article/434d2076489f49cc97d08541ea9b0923
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract To minimize neuromuscular electrical stimulation during electroporation-based treatments, the replacement of long monophasic pulses with bursts of biphasic high-frequency pulses in the range of microseconds was suggested in order to reduce m
Externí odkaz:
https://doaj.org/article/7eef9965c3d14f3eb3f9ce3f5b6bb255
Autor:
Aleksandra Cvetkoska, Alenka Maček-Lebar, Tamara Polajžer, Matej Reberšek, Weston Upchurch, Paul A. Iaizzo, Daniel C. Sigg, Damijan Miklavčič
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 12, p 490 (2023)
Electroporation is used in medicine for drug and gene delivery, and as a nonthermal ablation method in tumor treatment and cardiac ablation. Electroporation involves delivering high-voltage electric pulses to target tissue; however, this can cause ef
Externí odkaz:
https://doaj.org/article/ed371f09c7134048b7f0f5b6e52ad6ff
Publikováno v:
Acta Chimica Slovenica, Vol 68, Iss 4, Pp 753-764 (2021)
Electroporation is used to increase the permeability of the cell membrane through high-voltage electric pulses. Nowadays, it is widely used in different areas, such as medicine, biotechnology, and the food industry. Electroporation induces the format
Externí odkaz:
https://doaj.org/article/495fcc0bf9e643d193955dc4f465cbc1
Publikováno v:
Zdravniški Vestnik, Vol 90, Iss 7-8, Pp 410-419 (2021)
Zdravljenje atrijske fibrilacije (AF) je hitro razvijajoče se področje kardiologije, pri katerem smo priča stalnemu razvoju različnih oblik tehničnih izboljšav in multidisciplinarnega pristopa. Poleg iskanja najprimernejšega ablacijskega nači
Externí odkaz:
https://doaj.org/article/f504180ccd8e4140807b6e56ba03a04d
Autor:
Tamara Polajžer, Damijan Miklavčič
Publikováno v:
Vaccines, Vol 11, Iss 6, p 1036 (2023)
Traditionally, electroporation-based therapies such as electrochemotherapy (ECT), gene electrotransfer (GET) and irreversible electroporation (IRE) are performed with different but typical pulse durations—100 microseconds and 1–50 milliseconds. H
Externí odkaz:
https://doaj.org/article/e0b9b5e80c7a4de49a458368f6670a63