Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Damien Z. Soghoian"'
Autor:
Michael H. Guo, Prashanth Sama, Brenna A. LaBarre, Hrishikesh Lokhande, John Balibalos, Ci Chu, Xiaomi Du, Pouya Kheradpour, Charles C. Kim, Taylor Oniskey, Thomas Snyder, Damien Z. Soghoian, Howard L. Weiner, Tanuja Chitnis, Nikolaos A. Patsopoulos
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-23 (2022)
Abstract Background Multiple sclerosis (MS) is an autoimmune condition of the central nervous system with a well-characterized genetic background. Prior analyses of MS genetics have identified broad enrichments across peripheral immune cells, yet the
Externí odkaz:
https://doaj.org/article/b853f835c3b7425b97ee266ce7fa4c92
Autor:
Michael H. Guo, Prashanth Sama, Brenna A. LaBarre, Hrishikesh Lokhande, John Balibalos, Ci Chu, Xiaomi Du, Pouya Kheradpour, Charles C. Kim, Taylor Oniskey, Thomas Snyder, Damien Z. Soghoian, Howard L. Weiner, Tanuja Chitnis, Nikolaos A. Patsopoulos
Publikováno v:
Genome biology. 23(1)
Background Multiple sclerosis (MS) is an autoimmune condition of the central nervous system with a well-characterized genetic background. Prior analyses of MS genetics have identified broad enrichments across peripheral immune cells, yet the driver i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8d6172c01ed1a7ffe3535426ff4e54
https://pubmed.ncbi.nlm.nih.gov/35672799
https://pubmed.ncbi.nlm.nih.gov/35672799
Autor:
Howard L. Weiner, Ci Chu, Damien Z. Soghoian, Nikolaos A. Patsopoulos, Xiaomi Du, Pouya Kheradpour, Hrishikesh Lokhande, Tanuja Chitnis, Prashanth Sama, Michael H. Guo, Taylor K. Oniskey, Brenna A. LaBarre, Charles C. Kim, Thomas Snyder, John Balibalos
Multiple sclerosis (MS) is an autoimmune condition of the central nervous system with a well-characterized genetic background. Prior analyses of MS genetics have identified broad enrichments across peripheral immune cells, yet the driver immune subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a22b3701ab6423a38670359192a14790
https://doi.org/10.1101/2021.05.24.445445
https://doi.org/10.1101/2021.05.24.445445
Autor:
Damien Z. Soghoian, Bruce D. Walker, Faith Donaghey, Michael S. Seaman, Srinika Ranasinghe, Madelene Lindqvist, Daniel Kaufmann, Mary Carrington, Musie Ghebremichael, Filippos Porichis
Publikováno v:
Journal of Virology. 90:2208-2220
Antigen-specific CD4 + T helper cell responses have long been recognized to be a critical component of effective vaccine immunity. CD4 + T cells are necessary to generate and maintain humoral immune responses by providing help to antigen-specific B c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a01ecd0fbc9c75be1de6228c032d80f
https://doi.org/10.1128/jvi.02278-15
https://doi.org/10.1128/jvi.02278-15
Autor:
Mary Carrington, Bruce D. Walker, Damien Z. Soghoian, Daniel Karel, Carl M. Kadie, Oliver B. Davis, Ariel Goldenthal, Alicja Piechocka, Jian Peng, David Heckerman, Jonathan M. Carlson, Florencia Pereyra, Tien-Ho Lin, Charles E. DeZiel
Publikováno v:
Journal of Virology. 88:12937-12948
We investigated the hypothesis that the correlation between the class I HLA types of an individual and whether that individual spontaneously controls HIV-1 is mediated by the targeting of specific epitopes by CD8 + T cells. By measuring gamma interfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bba36e37bcc22ae49246fda40f2a099
https://doi.org/10.1128/jvi.01004-14
https://doi.org/10.1128/jvi.01004-14
Autor:
Ralf R. Schumann, Damien Z. Soghoian, Heiko Jessen, Srinika Ranasinghe, Franco Pissani, Hendrik Streeck, Isaiah Davis, Eric S. Rosenberg, Bruce T. Schultz, Galit Alter, Richard Lu, Arne Jessen, Carmen Zedlack, Alexander F. Oster, Miriam Schieffer
Publikováno v:
Journal of Virology. 88:7357-7366
Effector CD4 T cell responses have been shown to be critically involved in the containment and clearance of viral pathogens. However, their involvement in the pathogenesis of HIV infection is less clear, given their additional role as preferred viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e437b912e46ce2518ab7f0bbf0f0ff6
https://doi.org/10.1128/jvi.00728-14
https://doi.org/10.1128/jvi.00728-14
Autor:
Srinika Ranasinghe, Madelene Lindqvist, Sam Cutler, Michael Flanders, Steven G. Deeks, Damien Z. Soghoian, Hendrik Streeck, Alessandro Sette, Galit Alter, Ying Qi, Bjorn D. Kuhl, Richard Lu, Gregory Kranias, Isaiah Davis, Mary Carrington, Bruce D. Walker, John Sidney, Xiaojiang Gao
Publikováno v:
Nature medicine
The contribution of HLA class II-restricted CD4+ T cell responses to HIV immune control is poorly defined. Here, we delineated novel peptide-DRB1 restrictions in functional assays and analyzed the host genetic effects of HLA-DRB1 alleles on HIV virem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db3bc362da0c6d5f78c6974a57271f8
http://europepmc.org/articles/PMC3974408
http://europepmc.org/articles/PMC3974408
Autor:
Matthias I. Muller, Gregory Kranias, Damien Z. Soghoian, Madelene Lindqvist, Bjorn D. Kuhl, Jan van Lunzen, Michael Flanders, Donna L. Farber, Naomi Yudanin, Julian Schulze zur Wiesch, Galit Alter, Srinika Ranasinghe, Philip Hartjen, Friedrich Haag, Isaiah Davis, Hendrik Streeck, Samuel Cutler
Publikováno v:
Journal of Clinical Investigation. 122:3271-3280
HIV targets CD4 T cells, which are required for the induction of high-affinity antibody responses and the formation of long-lived B cell memory. The depletion of antigen-specific CD4 T cells during HIV infection is therefore believed to impede the de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e30dca8c3b6f579f649669e8caeec00
https://doi.org/10.1172/jci64314
https://doi.org/10.1172/jci64314
Autor:
Michael Flanders, Sam Cutler, Madelene Lindqvist, Bruce D. Walker, Damien Z. Soghoian, David Heckerman, Srinika Ranasinghe, Musie Ghebremichael, Florencia Pereyra, Hendrik Streeck, Isaiah Davis
Publikováno v:
Journal of Virology. 86:277-283
A successful prophylactic vaccine is characterized by long-lived immunity, which is critically dependent on CD4 T cell-mediated helper signals. Indeed, most licensed vaccines induce antigen-specific CD4 T cell responses, in addition to high-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7658e63bb1ee00bd9c1d3c4bf7e28
https://doi.org/10.1128/jvi.05577-11
https://doi.org/10.1128/jvi.05577-11
Autor:
Ulf Dittmer, Sebastien M. Maloveste, Agnès-Laurence Chenine, Galit Alter, Diane L. Bolton, Nelson L. Michael, Bruce T. Schultz, Hendrik Streeck, Jeffrey E. Teigler, Alexander F. Oster, Michael A. Eller, Mary A. Marovich, Richard Lu, Merlin L. Robb, Susan R. Johnson, Damien Z. Soghoian
CD4 + T cells play a pivotal role in the control of chronic viral infections. Recently, nontraditional CD4 + T cell functions beyond helper effects have been described, and a role for cytolytic CD4 + T cells in the control of HIV infection has been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66e8292b9f898ef09d008d4475a0fff
https://www.ncbi.nlm.nih.gov/pubmed/25972560
https://www.ncbi.nlm.nih.gov/pubmed/25972560