Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Damien M Laudier"'
Autor:
Warren W Hom, Melanie Tschopp, Huizi A Lin, Philip Nasser, Damien M Laudier, Andrew C Hecht, Steven B Nicoll, James C Iatridis
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217357 (2019)
Back pain commonly arises from intervertebral disc (IVD) damage including annulus fibrosus (AF) defects and nucleus pulposus (NP) loss. Poor IVD healing motivates developing tissue engineering repair strategies. This study evaluated a composite injec
Externí odkaz:
https://doaj.org/article/60a6f1d18cd543649c340d22db7e7a47
Autor:
Svenja Illien-Junger, Fabrizio Grosjean, Damien M Laudier, Helen Vlassara, Gary E Striker, James C Iatridis
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64302 (2013)
OBJECTIVE:Diabetes and low back pain are debilitating diseases and modern epidemics. Diabetes and obesity are also highly correlated with intervertebral disc (IVD) degeneration and back pain. Advanced-glycation-end-products (AGEs) increase reactive-o
Externí odkaz:
https://doaj.org/article/504515786ae743ccabb7522b11ccc78c
Autor:
Jonathan Y Lee, Zuping Zhou, Peter J Taub, Melissa Ramcharan, Yonghui Li, Takintope Akinbiyi, Edward R Maharam, Daniel J Leong, Damien M Laudier, Takuya Ruike, Phillip J Torina, Mone Zaidi, Robert J Majeska, Mitchell B Schaffler, Evan L Flatow, Hui B Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17531 (2011)
We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers
Externí odkaz:
https://doaj.org/article/ae65fd77be85486589f50a62da92add4
Autor:
Alon Lai, Denise Iliff, Kashaf Zaheer, Jennifer Gansau, Damien M. Laudier, Venetia Zachariou, James C. Iatridis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1762 (2024)
Chronic painful intervertebral disc (IVD) degeneration (i.e., discogenic pain) is a major source of global disability needing improved knowledge on multiple-tissue interactions and how they progress in order improve treatment strategies. This study u
Externí odkaz:
https://doaj.org/article/75d9ffc03fd64012be12f8a682c69cce
Autor:
Divya Krishnamoorthy, Robert C. Hoy, Devorah M. Natelson, Olivia M. Torre, Damien M. Laudier, James C. Iatridis, Svenja Illien-Jünger
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 12 (2018)
Back pain is a leading cause of disability and is strongly associated with intervertebral disc (IVD) degeneration. Reducing structural disruption and catabolism in IVD degeneration remains an important clinical challenge. Pro-oxidant and structure-mo
Externí odkaz:
https://doaj.org/article/c0b99b40da8241b3acb5ad2e352222ae
Autor:
Zachary S. Gallate, Danielle N. D'Erminio, Philip Nasser, Damien M. Laudier, James C. Iatridis
Publikováno v:
JOR SPINE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91409fd4d36858b2128bb7bb3ba059ef
https://doi.org/10.1002/jsp2.1254
https://doi.org/10.1002/jsp2.1254
Autor:
Dalin Wang, Alon Lai, Jennifer Gansau, Alan C. Seifert, Jazz Munitz, Kashaf Zaheer, Neharika Bhadouria, Yunsoo Lee, Philip Nasser, Damien M. Laudier, Nilsson Holguin, Andrew C. Hecht, James C. Iatridis
BACKGROUND CONTEXT: Endplate (EP) injury plays critical roles in painful IVD degeneration since Modic changes (MCs) are highly associated with pain. Models of EP microfracture that progress to painful conditions are needed to better understand pathop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898f51172a42b916c06588adc5c1d676
https://doi.org/10.1101/2023.01.27.525924
https://doi.org/10.1101/2023.01.27.525924
Autor:
Kristen L. Howell, Matthias A. Zumstein, Helen L. Moser, Adam C. Abraham, Alice H. Huang, Leesa M. Galatz, Damien M. Laudier
Publikováno v:
J Orthop Res
Rotator cuff supraspinatus tendon injuries are common with high rates of anatomic failure after surgical repair. The purpose of the study was to define clinically relevant features of a mouse model of supraspinatus tendon injury to determine painful,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0568e98e6088fe49a35044d8feed4ee7
https://doi.org/10.1002/jor.24769
https://doi.org/10.1002/jor.24769
Autor:
Christopher J. Panebianco, Sanjna Rao, Warren W. Hom, James H. Meyers, Tiffany Y. Lim, Damien M. Laudier, Andrew C. Hecht, Michael D. Weir, Jennifer R. Weiser, James C. Iatridis
Publikováno v:
Biomaterials. 287
Discectomy procedures alleviate disability caused by intervertebral disc (IVD) herniation, but do not repair herniation-induced annulus fibrosus (AF) defects. Cell therapy shows promise for IVD repair, yet cell delivery biomaterials capable of sealin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b76d28af83fe90d9b0723f2685091e
https://pubmed.ncbi.nlm.nih.gov/35759923
https://pubmed.ncbi.nlm.nih.gov/35759923
Autor:
Dalin Wang, Alon Lai, Jennifer Gansau, Philip Nasser, Yunsoo Lee, Damien M. Laudier, James C. Iatridis
Publikováno v:
J Mech Behav Biomed Mater
Back pain is often associated with intervertebral disc (IVD) degeneration, and IVD degeneration phenotypes are commonly characterized by annulus fibrosus (AF)-driven and endplate (EP)-driven phenotypes. Few studies of EP injury exist in animal models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a23e6517e8c86964181d0f011e9543
https://pubmed.ncbi.nlm.nih.gov/35462160
https://pubmed.ncbi.nlm.nih.gov/35462160