Výsledky vyhledávání - "Damien Le Nihouannen"

Akademický článek

Regulation of Osteoclast Growth and Fusion by mTOR/raptor and mTOR/rictor/Akt

Autor: Kerstin Tiedemann, Damien Le Nihouannen, Jenna E. Fong, Osama Hussein, Jake E. Barralet, Svetlana V. Komarova

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 5 (2017)

Osteoclasts are giant bone cells formed by fusion from monocytes and uniquely capable of a complete destruction of mineralized tissues. Previously, we have demonstrated that in energy-rich environment not only osteoclast fusion index (the number of n

Externí odkaz: https://doaj.org/article/8ad46d5f4e494c1bb7ff86ca678fd560

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Akademický článek

Moderate excess of pyruvate augments osteoclastogenesis

Autor: Jenna E. Fong, Damien Le Nihouannen, Kerstin Tiedemann, Gulzhakhan Sadvakassova, Jake E. Barralet, Svetlana V. Komarova

Publikováno v: Biology Open, Vol 2, Iss 4, Pp 387-395 (2013)

Summary Cell differentiation leads to adaptive changes in energy metabolism. Conversely, hyperglycemia induces malfunction of many body systems, including bone, suggesting that energy metabolism reciprocally affects cell differentiation. We investiga

Externí odkaz: https://doaj.org/article/ab1bea60ea58433d99e449d0b5ba3998

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Layer‐by‐layer bioassembly of poly(lactic) acid membranes loaded with coculture of HBMSCs and EPCs improves vascularization in vivo

Autor: Jean-Christophe Fricain, Raphaël Devillard, Reine Bareille, Maxime Seimbille, Vera Guduric, Noélie B. Thebaud, Ognjan Luzanin, Joanna Babilotte, Damien Le Nihouannen, Sylvie Rey, Robin Siadous, Sylvain Catros

Publikováno v: Journal of Biomedical Materials Research Part A
Journal of Biomedical Materials Research Part A, Wiley, 2019, 107 (12), pp.2629-2642. ⟨10.1002/jbm.a.36769⟩

International audience; Layer-by-layer (LBL) BioAssembly method was developed to enhance the control of cell distribution within 3D scaffolds for tissue engineering applications. The objective of this study was to evaluate in vivo the development of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1fc3f48d064408ed59a925bd32ad35
https://doi.org/10.1002/jbm.a.36769

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Development and characterization of a PLGA-HA composite material to fabricate 3D-printed scaffolds for bone tissue engineering

Autor: Samantha Roques, Sylvain Catros, Rémy Agniel, Manuel Gaudon, Vera Guduric, Benoit Martin, Reine Bareille, Joanna Babilotte, Damien Le Nihouannen, Valérie Héroguez, Marc Dussauze

Publikováno v: Materials Science and Engineering: C
Materials Science and Engineering: C, Elsevier, 2021, 118, 111334 (13 p.). ⟨10.1016/j.msec.2020.111334⟩

International audience; Additive manufacturing is a rising field in bone tissue engineering. Additive fabrication offers reproducibility, high precision and rapid manufacture of custom patient-specific scaffolds. The development of appropriate compos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8206e2cb110bef43b49d0d41e66846
http://hdl.handle.net/20.500.12278/19577

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Characterization of printed PLA scaffolds for bone tissue engineering

Autor: Sylvain Catros, Reine Bareille, Jean-Christophe Fricain, Vera Guduric, Agathe Grémare, Simon Latour, Valérie Héroguez, Nicolas L'Heureux, Damien Le Nihouannen

Publikováno v: Journal of Biomedical Materials Research Part A. 106:887-894

Autografts remain the gold standard for orthopedic transplantations. However, to overcome its limitations, bone tissue engineering proposes new strategies. This includes the development of new biomaterials such as synthetic polymers, to serve as scaf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0fe7ee9dd69ac1322d9c585c6afd022
https://doi.org/10.1002/jbm.a.36289

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A Unique Triculture Model to Study Osteoblasts, Osteoclasts, and Endothelial Cells

Autor: Reine Bareille, Bruno Paiva dos Santos, Audrey Aussel, Joëlle Amédée, Damien Le Nihouannen, Agathe Grémare, Noélie B. Thebaud

Publikováno v: Tissue Engineering Part C: Methods
Tissue Engineering Part C: Methods, Mary Ann Liebert, 2019, 25 (7), pp.421-432. ⟨10.1089/ten.TEC.2018.0301⟩

International audience; In this article, we first developed a new medium to culture together primary human osteoblastic, osteoclastic, and endothelial cells (ECs) chosen to represent the three major bone cell tissues. Indeed, no study has been conduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9e0ceaf1ec49639c7f3b7a69ce2336
https://www.hal.inserm.fr/inserm-02863405

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3D printed polymer–mineral composite biomaterials for bone tissue engineering: Fabrication and characterization

Autor: Jean-Christophe Fricain, Adrien Naveau, Joanna Babilotte, Sylvain Catros, Damien Le Nihouannen, Vera Guduric

Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials
Journal of Biomedical Materials Research Part B: Applied Biomaterials, Wiley, 2019, 107 (8), pp.2579-2595. ⟨10.1002/jbm.b.34348⟩

International audience; Applications in additive manufacturing technologies for bone tissue engineering applications requires the development of new biomaterials formulations. Different three-dimensional (3D) printing technologies can be used and pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4f2efc307f39d2a268684ba2bdbe4e
https://www.hal.inserm.fr/inserm-02870512

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Anti-osteoclastic effects of C-glucosidic ellagitannins mediated by actin perturbation

Autor: Christophe Le Clainche, Denis Deffieux, Daniela Melanie Delannoy López, Elisabeth Génot, Thierry Dakhli, Damien Le Nihouannen, Stéphane Quideau, Isabelle Fremaux, Pierre Jurdic, Dan Georgess, Pirjo Spuul

Publikováno v: European Journal of Cell Biology
European Journal of Cell Biology, 2018, ⟨10.1016/j.ejcb.2018.09.003⟩

Actin subunits assemble into actin filaments whose dynamics and three-dimensional architectures are further regulated by a variety of cellular factors to establish the functional actin cytoskeleton. The C-glucosidic ellagitannin vescalagin and its si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07d284bc1aacfe9760d1c7907407f0f
https://hal.science/hal-02178892

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Characterization of printed PLA scaffolds for bone tissue engineering

Autor: Agathe, Grémare, Vera, Guduric, Reine, Bareille, Valérie, Heroguez, Simon, Latour, Nicolas, L'heureux, Jean-Christophe, Fricain, Sylvain, Catros, Damien, Le Nihouannen

Publikováno v: Journal of biomedical materials research. Part A. 106(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e7c036ef66f68708cf137388e334e01e
https://pubmed.ncbi.nlm.nih.gov/29105943

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Ascorbic acid accelerates osteoclast formation and death

Autor: Svetlana V. Komarova, Jenna E. Fong, Damien Le Nihouannen, Jake E. Barralet

Publikováno v: Bone. 46:1336-1343

Ascorbic acid (AA) plays a key role in bone formation. However controversy remains about the effect of AA on cells responsible for bone destruction, osteoclasts. We investigated the effect of AA on osteoclastogenesis using primary mouse bone marrow c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41438bdc6b17a1c3a1cb83b88f07a305
https://doi.org/10.1016/j.bone.2009.11.021

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