Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Damien J. Dunnington"'
Publikováno v:
International Journal of Cancer
Although numerous animal tumor models have been used to study colon carcinoma, few display metastatic properties. We have characterized an animal tumor model that has 3 properties essential for the study of metastasis of colon carcinoma cells: epithe
Autor:
Paul Monaghan, Damien J. Dunnington, Barry A. Gusterson, Philip S. Rudland, Kim U, Michael J. O'Hare
Publikováno v:
British Journal of Cancer
A new cell line Rat mammary (Rama) 900 was isolated from the ascitic version of the SMT-2A metastasising rat mammary tumour by stepwise adaptation of the tumour cells to tissue culture. The cells grew mainly as loosely-adherent aggregates, and were d
Autor:
Leonard W. Rozamus, Juan I. Luengo, Richard Heys, Annalisa Hand, Randall K. Johnson, Arthur Shu, Damien J. Dunnington, Karla D'Alessio, Polongpon Kongsaeree, Dennis A. Holt, Hwa-Kwo Yen, Tonie Newman-Tarr, Terence Porter, Jon Clardy, Mark Alan Levy, Jungwon Choi, Dennis S. Yamashita, Alison Badger, Mary J. Bossard, Arda Konialian Beck, Leo F. Faucette
Publikováno v:
Chemistry & Biology. (7):471-481
Background : Rapamycin is an immunosuppressant natural product, which blocks T -cell mitogenesis and yeast proliferation. In the cytoplasm, rapamycin binds to the immunophilin FKBP12 and the complex of these two molecules binds to a recently discover
Publikováno v:
JNCI: Journal of the National Cancer Institute.
Myoepithelial-like cell lines from normal mammary glands of neonatal Ludwig Wistar rats, rat mammary (Rama) 401 and Rama 704E, were injected into fat pads of syngeneic animals or were single-cell cloned in vitro. Rama 401 produced tumors that were pr
Autor:
Paul Monaghan, Damien J. Dunnington, Christine M. Hughes, Philip S. Rudland, Untae Kim, E. Jane Ormerod
Publikováno v:
JNCI: Journal of the National Cancer Institute.
A series of WF rat mammary tumors comprising one transplantable nonmetastasizing line (MT-W9), two predominantly lymphatic (SMT-2A and SMT-077) and one lymphatic and hematogenous (MT-450) metastasizing transplantable lines, and 7,12-dimethylbenz[a]an
Publikováno v:
Biochemical and biophysical research communications. 165(1)
Proliferation of SW13 human adrenocortical carcinoma cells under anchorage independent conditions was stimulated in a dose-dependent manner by treatment with the cholesterol biosynthesis inhibitor mevinolin. Induction of 3-hydroxy-3-methylglutaryl co
Publikováno v:
JNCI: Journal of the National Cancer Institute.
The spontaneous production of elongated derivatives by cuboidal rat mammary epithelial cells was examined with the use of a series of single-cell clones grown in tissue culture. Four representative cell lines derived from a 7,12-dimethylbenz[a]anthra